BARALDI, Pier Giovanni
 Distribuzione geografica
Continente #
NA - Nord America 44.368
AS - Asia 22.061
EU - Europa 20.432
SA - Sud America 3.383
AF - Africa 513
Continente sconosciuto - Info sul continente non disponibili 512
OC - Oceania 45
Totale 91.314
Nazione #
US - Stati Uniti d'America 43.458
FI - Finlandia 8.286
SG - Singapore 7.709
CN - Cina 5.947
DE - Germania 3.425
BR - Brasile 2.609
UA - Ucraina 2.333
VN - Vietnam 2.166
HK - Hong Kong 1.954
TR - Turchia 1.836
GB - Regno Unito 1.365
IT - Italia 1.330
SE - Svezia 947
RU - Federazione Russa 908
FR - Francia 808
IN - India 466
JP - Giappone 463
CA - Canada 399
MX - Messico 351
BD - Bangladesh 350
AR - Argentina 275
PL - Polonia 260
ZA - Sudafrica 207
IQ - Iraq 179
NL - Olanda 155
ID - Indonesia 132
ES - Italia 120
CO - Colombia 113
PK - Pakistan 111
BE - Belgio 103
EC - Ecuador 94
MA - Marocco 89
TW - Taiwan 87
SA - Arabia Saudita 80
VE - Venezuela 76
CL - Cile 70
UZ - Uzbekistan 66
MY - Malesia 63
KR - Corea 57
LT - Lituania 57
PH - Filippine 54
PY - Paraguay 53
AE - Emirati Arabi Uniti 49
CZ - Repubblica Ceca 49
EG - Egitto 47
AT - Austria 37
CR - Costa Rica 36
IL - Israele 36
TN - Tunisia 36
AU - Australia 34
KE - Kenya 33
IR - Iran 30
PE - Perù 30
BO - Bolivia 28
JM - Giamaica 27
JO - Giordania 27
UY - Uruguay 27
NP - Nepal 26
IE - Irlanda 25
EU - Europa 24
TH - Thailandia 21
AZ - Azerbaigian 20
GR - Grecia 20
CH - Svizzera 19
RO - Romania 19
DZ - Algeria 18
ET - Etiopia 18
KZ - Kazakistan 17
PS - Palestinian Territory 17
PT - Portogallo 17
AL - Albania 16
HU - Ungheria 14
TT - Trinidad e Tobago 14
BH - Bahrain 13
KG - Kirghizistan 13
LB - Libano 13
OM - Oman 13
PA - Panama 13
BG - Bulgaria 12
HN - Honduras 12
MD - Moldavia 12
SK - Slovacchia (Repubblica Slovacca) 12
SY - Repubblica araba siriana 11
BY - Bielorussia 10
HR - Croazia 10
LV - Lettonia 10
NO - Norvegia 10
NZ - Nuova Zelanda 10
AO - Angola 9
DO - Repubblica Dominicana 9
GT - Guatemala 9
RS - Serbia 9
SN - Senegal 9
SV - El Salvador 9
MN - Mongolia 8
NI - Nicaragua 8
CI - Costa d'Avorio 7
DK - Danimarca 6
MT - Malta 6
MU - Mauritius 6
Totale 90.711
Città #
Helsinki 7.702
Singapore 5.035
Ashburn 4.178
Woodbridge 3.789
Fairfield 3.580
Dallas 2.783
San Jose 2.505
Houston 2.490
Jacksonville 2.455
Chandler 2.073
Ann Arbor 1.911
Hong Kong 1.831
Santa Clara 1.747
Beijing 1.610
Seattle 1.532
Wilmington 1.378
Cambridge 1.093
Council Bluffs 1.054
Izmir 805
Nanjing 776
Ho Chi Minh City 694
Los Angeles 545
Princeton 516
Hanoi 494
New York 478
Tokyo 423
Boardman 406
Lauterbourg 396
Munich 367
San Diego 323
Ferrara 271
Shenyang 263
Milan 256
São Paulo 249
Shanghai 226
Hefei 220
Nanchang 214
Warsaw 209
Mexico City 205
Tianjin 182
London 179
Orem 158
Hebei 157
Falkenstein 154
San Mateo 153
Changsha 149
Chicago 147
Bremen 144
Addison 141
Brooklyn 122
Jiaxing 121
Frankfurt am Main 115
Dearborn 114
Dong Ket 114
The Dalles 114
Turku 112
Jinan 111
Montreal 108
Toronto 108
Philadelphia 103
Buffalo 99
Chennai 99
Brussels 98
Da Nang 95
Atlanta 90
Johannesburg 90
Amsterdam 88
Baghdad 88
Haiphong 88
Falls Church 86
Moscow 86
Norwalk 84
Rio de Janeiro 84
Phoenix 81
San Francisco 81
Kunming 79
Redwood City 78
Zhengzhou 76
Denver 75
Guangzhou 72
Stockholm 66
Boston 62
Taipei 60
Mountain View 59
Poplar 58
Tashkent 58
Manchester 57
Brasília 55
Belo Horizonte 54
Mumbai 53
Ningbo 51
Jakarta 48
Auburn Hills 47
Orange 47
Hải Dương 46
Verona 45
Des Moines 44
Rome 44
Dhaka 43
Ankara 42
Totale 62.644
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.113
1,4-Diketones via Isoxazole Intermediates 3.082
1,2,3-triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: A new class of A(2A) adenosine receptor antagonists 3.057
Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale Distamicina A 1.971
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 537
The use of phase-transfer catalysis for the N-alkylation of indole. 524
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 343
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 330
A glance at adenosine receptors: Novel target for antitumor therapy 320
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 315
A new, efficient synthesis of muscimol (5-ammoniomethylisoxazol-3-olate). 309
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 304
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 301
A3 adenosine receptor antagonists: History and future perspectives 296
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 296
A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones 294
The A3 adenosine receptor: history and perspectives 294
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 284
A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin. 284
3,5-Disubstituted isoxazoles as a latent aldol moiety: Application to the synthesis of (±)-[6]-gingerol 277
A formal total synthesis (±)-forskolin through [3+2] nitrile oxide cycloaddition chemistry 277
Azaprostaglandin Analogues. Synthesis and Biological Properties of 11-Azaprostaglandin Derivatives 274
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 272
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 272
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 270
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 268
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 267
Adenosine receptors and human melanoma 263
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 262
2,3a,5,6,7,7a-Hexahydro-3H,4H-benzothiophene-3,4-dione and cyclopenta[b]tetrahydrothiophene-3,4-dione enolate anions as synthetic equivalents to cyclohex-2-enone and cyclopent-2-enone C-2-carbanions. 261
Allosteric modulators for the A1-adenosine receptor 261
A [3 + 2] nitrile oxide cycloaddition approach to retinoids 259
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 259
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 258
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders 257
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 257
3,5-Disubstituted Isoxazoles as Synthons for (±)-Pyrenophorin and (±)-Vermiculine Synthesis 253
A new nitrile oxide based synthesis of the antitumor agent geiparvarin 251
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 250
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 249
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 248
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 246
Allosteric enhancers for A(1) adenosine receptor 245
DNA minor groove binders as potential antitumor and antimicrobial agents 245
2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization 245
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 245
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 245
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 244
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 243
Blockade of A2A receptors plus L-DOPA after nigrostriatal lesion results in GAD67 mRNA changes different from L-DOPA alone in the rat globus pallidus and substantia nigra reticulata 240
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 239
A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives 238
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 236
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 235
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 235
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 231
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 231
Active γ-manganese dioxide promoted conversion of 4,5-dihydro-1,2-oxazoles to 1,2-oxazoles. 231
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 231
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 229
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 229
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 229
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 229
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 228
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 228
null 227
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 227
Hybrid molecules between distamycin A and active moieties of antitumor agents 227
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 226
Hybrid molecules based on distamycin A as potential antitumor agents 226
Carboxyl activation in peptide synthesis using 4-oximino-pyrazol-5-ones 225
Current status of A1 adenosine receptor allosteric enhancers 225
[3H]-MRE 2029-F20, a novel selective antagonist radioligand, for the pharmacological and biochemical characterization of A2B receptors. 223
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 222
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 222
A one-pot glycosylation of tetrahydropyranyl (THP) ether intermediates 221
Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates. 221
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 221
A new simple synthesis of a-substituted acrylonitriles 220
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 219
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 219
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 219
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 218
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 218
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 217
Methyl 4-oxothiolane-3-carboxylate and methyl 2-methyl-4-oxothiolane-3- carboxylate anions as synthetic equivalents of α-acrylate and α-crotonate anions. Formal synthesis of integerrinecic acid 216
Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H)-furanones and 3(2H)-furanimines 216
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 216
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 216
A new synthetic approach to indazole synthesis 216
[3H]MRE2029F20 a new selective antagonist radioligand for the human A2B adenosine receptors. 215
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 215
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 214
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 212
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 212
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 212
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 212
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 211
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 210
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors 210
Totale 35.342
Categoria #
all - tutte 360.082
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 3.576
Totale 363.658


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20224.935 0 470 372 291 373 250 208 243 197 361 528 1.642
2022/20234.800 508 249 108 646 881 773 145 390 611 31 286 172
2023/20242.411 243 307 129 82 170 287 95 394 28 60 56 560
2024/20259.331 291 294 752 335 1.154 770 273 638 1.285 1.084 1.377 1.078
2025/202636.487 2.653 1.709 4.045 3.576 3.659 1.892 3.275 1.339 9.919 3.179 886 355
2026/20272.211 798 1.413 0 0 0 0 0 0 0 0 0 0
Totale 91.314