CACCIARI, Barbara
 Distribuzione geografica
Continente #
NA - Nord America 8.062
EU - Europa 1.971
AS - Asia 1.850
SA - Sud America 7
OC - Oceania 4
AF - Africa 2
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.898
Nazione #
US - Stati Uniti d'America 8.029
CN - Cina 968
UA - Ucraina 662
TR - Turchia 439
DE - Germania 367
SG - Singapore 311
GB - Regno Unito 271
SE - Svezia 215
FI - Finlandia 149
IT - Italia 148
VN - Vietnam 62
FR - Francia 39
PL - Polonia 38
CA - Canada 31
HK - Hong Kong 26
RU - Federazione Russa 22
BE - Belgio 19
ID - Indonesia 17
IN - India 11
LT - Lituania 9
NL - Olanda 9
BR - Brasile 4
CZ - Repubblica Ceca 4
IE - Irlanda 4
ES - Italia 3
IR - Iran 3
KR - Corea 3
TW - Taiwan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AT - Austria 2
AU - Australia 2
BG - Bulgaria 2
CH - Svizzera 2
IQ - Iraq 2
NZ - Nuova Zelanda 2
BD - Bangladesh 1
BY - Bielorussia 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
JP - Giappone 1
LB - Libano 1
MD - Moldavia 1
ME - Montenegro 1
MX - Messico 1
PA - Panama 1
PH - Filippine 1
PT - Portogallo 1
RO - Romania 1
SD - Sudan 1
UZ - Uzbekistan 1
Totale 11.898
Città #
Woodbridge 977
Fairfield 914
Houston 770
Jacksonville 711
Ashburn 659
Chandler 593
Ann Arbor 488
Wilmington 356
Seattle 350
Santa Clara 272
Cambridge 264
Nanjing 243
Singapore 234
Izmir 220
Princeton 158
Boardman 111
Beijing 109
San Diego 89
Shenyang 77
Nanchang 67
Dong Ket 61
Jiaxing 41
Milan 40
Shanghai 39
Los Angeles 37
San Mateo 37
Ferrara 34
Hebei 34
Tianjin 34
Kunming 32
Warsaw 31
Changsha 30
Dearborn 30
Jinan 28
Zhengzhou 27
Falls Church 26
Hong Kong 25
Norwalk 22
Brussels 19
Helsinki 19
Philadelphia 19
Ningbo 18
Addison 17
Guangzhou 15
Jakarta 15
Munich 15
New York 15
Bremen 14
Mountain View 14
Taizhou 14
London 13
Verona 13
Montréal 12
Redwood City 12
Toronto 12
Indiana 11
Washington 11
Augusta 9
Mcallen 9
Orange 9
Auburn Hills 8
Des Moines 8
Redmond 8
Tappahannock 7
Frankfurt am Main 6
Hangzhou 6
Leawood 6
Amsterdam 5
Düsseldorf 5
Haikou 5
Kilburn 5
Weihai 5
Chiswick 4
Dublin 4
Hefei 4
Lanzhou 4
Ottawa 4
Rome 4
San Francisco 4
Yellow Springs 4
Brno 3
Changchun 3
Ferrara di Monte Baldo 3
Fuzhou 3
Las Vegas 3
Monmouth Junction 3
Nantong 3
New Bedfont 3
Villafranca Padovana 3
Ardabil 2
Baghdad 2
Catania 2
Chicago 2
Cosenza 2
Edinburgh 2
Hounslow 2
Hsinchu 2
Misterbianco 2
Mumbai 2
Padova 2
Totale 8.730
Nome #
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 364
1,2,3-triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: A new class of A(2A) adenosine receptor antagonists 297
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 169
5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors 159
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 142
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 131
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 129
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and Structurally Simplified Analogs. Chemistry and SAR Profile as Adenosine Receptor Antagonists 129
Synthesis and antitumor activity of novel distamycin derivatives 126
The influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl moiety on the adenosine receptors affinity profile of pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c] pyrimidine derivatives 125
Synthesis and calcium antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(nitrogenous heteroaryl)-3,5-pyridine dicarboxylates. 119
New potent and selective human adenosine A3 receptor antagonists. 119
null 118
DNA minor groove alkylating agents structurally related to distamycin A 117
A new synthetic approach to indazole synthesis 116
8-(2-Furyl)adenine derivatives as A₂A adenosine receptor ligands 115
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 115
Oligonucleotides and oligonucleotide conjugates: A new approach for cancer treatment 114
Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs) 112
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A1 adenosine receptor antagonists 110
Nitrile oxide [3 + 2] cycloaddition: application to the synthesis of 6-substituted 3(2H)-pyridazinones and 6-substituted 4,5-dihydro-4-hydroxy-3(2H)-pyridazinones 107
Design, synthesis and biological activity of a pyrrolo[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid 107
Carbon nanotube substrates boost neuronal electrical signaling 107
Resolution of a CPzI precursor, synthesis and biological evaluation of (+) and (-)-N-Boc-CPzI: A further validation of the relationship between chemical solvolytic stability and cytotoxicity 107
Structure-activity relationship of novel tallimustine derivatives: Synthesis and antitumor activity 106
DNA minor-groove binders: results and design of new antitumor agents 106
Selective binding to human genomic sequences of two synthetic analogues structurally related to U-71184 and adozelesin 106
null 104
An efficient procedure for the synthesis of 5H-6-substituted-pyrazolo[1,5-d]-1,2,4-triazine-4,7-diones 104
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors 104
A2A-adenosine receptor reserve for coronary vasodilation 104
Synthesis and preliminary biological evaluation of [H-3]-MRE 3008-F20: the first high affinity radioligand antagonist for the human A(3) adenosine receptors 103
Facile and versatile route to the synthesis of fused 2-pyridones: Useful intermediates for polycyclic sytems 102
Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines 102
Ethyl-(R,S)-5-acetyl-4,5-dihydro-3-isoxazole acetate 100
Ethyl (R,S)-5-acetyl-4,5-dihydro-3-isoxazoleacetate 100
Solid lipid microparticles for the stability enhancement of a dopamine prodrug 100
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: A complete structure-activity profile 99
Linear and nonlinear 3D-QSAR approaches in tandem with ligand-based homology modeling as a computational strategy to depict the pyrazolo-triazolo- pyrimidine antagonists binding site of the human adenosine A2A receptor 99
Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c] [1,4]benzodiazepines 98
New potent and selective human adenosine A3 receptor antagonists 98
Synthesis and properties of substituted CBI analogs of CC-1065 and the duocarmycins incorporating the 7-methoxy-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (MCBI) alkylation subunit: Magnitude of electronic effects on the functional reactivity 97
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 96
Chemical synthesis of [13C]daidzein. 96
The Significance of 2-Furyl Ring Substitution with a 2-(para-substituted) Aryl Group in a New Series of Pyrazolo-triazolo-pyrimidines as Potent and Highly Selective hA3 Adenosine Receptors Antagonists: New Insights into Structure-Affinity Relationship and Receptor-Antagonist Recognition 96
Structure Activity Relationship of 4-Amino-2-thiopyrimidine Derivatives as Platelet Aggregation Inhibitors 96
CC-1065 and the duocarmycins: recent developments 95
Synthesis and Biological Evaluation of a New Series of 1,2,4-Triazolo[1,5-a]-1,3,5-triazines as Human A(2A) Adenosine Receptor Antagonists with Improved Water Solubility 95
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes 94
Antiproliferative effects of novel synthetic nucleobase analogues on U937 Histiocytic lymphoma cell line 93
Synthesis, biological studies and molecular modeling investigation of 1,3-dimethyl-2,4-dioxo-6-methyl-8-(substituted) 1,2,3,4-tetrahydro [1,2,4]-triazolo [3,4-f]-purines as potential adenosine receptor antagonists 92
Exploring Potency and Selectivity Receptor Antagonist Profiles Using a Multilabel Classification Approach: The Human Adenosine Receptors as a Key Study 92
Synthesis of pyridazine derivatives through the unexpected intermediate 5-amino-4-cyano-2,3-dihydro-furan-2,3-disulfonic acid disodium salt 92
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 91
Cosmetic preservation and structure-activity relationships of 4-diazo-pyrazole-5-carboxamides 91
Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling 91
null 90
Recent developments in the field of adenosine receptor ligands 89
1H-pyrazolo[4,3-d]pyrimidine-7(6H)-one and 5H-pyrazolo[4,3-d] 1,2,3-triazin-4(3H)-one derivatives. Synthesis and in vitro biological activity at adenosine A1 and A2a receptors 89
Schematic overview of oligosaccharides, with survey on their major physiological effects and a focus on milk ones 89
null 87
A(3) adenosine receptor ligands: History and perspectives 87
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 87
Carbon Nanotubes Carrying Cell-Adhesion Peptides do not Interfere with Neuronal Functionality 86
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 86
Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process 84
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 83
Binding affinity of adenosine receptor agonists and antagonists at human cloned A3 adenosine receptors 83
Substituted 6-amino-thiouracils as new P2Y(12) receptor antagonists 82
7-sobstituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonist: importance of modifications at the side chain on the activity and solubility. 81
A(1) and A(3) adenosine receptor agonists: an overview 80
Novel N-6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A(3) adenosine receptors 79
Pyrazolo [4,3-E]1,2,4-triazolo[1,5-c]pyrimidine derivates a new class of potent and selective human A3 adenosine receptor antagonists. 79
[3H]MRE3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 79
Synthesis and cardiodepressant activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pentatomic-heteroaryl)-3,5-pyridinedicarboxylates. 2 78
null 77
Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists 76
Unusual Ring-Opening Reaction of 6,7-Dihydrothieno[3,2-d]pyrimidine- 2,4-dione Derivatives Leading to 5-(Alkylthio)-6-vinyluracils 75
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]-pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists 74
Synthesis and Biological Activity of a New Series of N6-Arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-Carboxamido Derivatives of Adenosine-5'-N-ethyluronamide as A1 and A3 Adenosine Receptor Agonists 74
A2Aadenosine receptor antagonists as therapeutic candidates: Are they still an interesting challenge? 73
Rationale design of new human adenosione A3 receptor antagonists through a CoMFA model. 72
Pyridazine nucleus: a pharmacophoric moiety for bio-active compounds 72
Synthesis, binding and thermodynamic studies of new highly selective A2A adenosine receptor antagonists 72
Synthesis, antibacterial activity and structure-activity relationships of N-substituted 4-diazopyrazole-5-carboxamides. 2 71
Heterocyclic analogs of DNA minor groove alkylating agents 71
Synthesis, biological and modeling studies of new water soluble hA3 adenosine receptor antagonists. 71
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives: Potent and selective A2A adenosine antagonists 71
Synthesis and molecular investigation of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivates as human A3 adenosine receptor antagonists. 70
Synthesis, cytotoxicity and antitumor activity of some new simplified pyrazole analogs of the antitumor agent CC-1065. Effect of an hydrophobic group on antitumor activity 68
Comparative molecular field analysis (CoMFA) of a series of selective adenosine receptor A(2A) antagonists 68
Synthesis and molecular investigation of new pyrazolo[4,3-e]1,2,4,-triazolo[1,5-c]pyrimidine derivates as human A3 adenosine receptor antagonists. 68
Triazolo-triazine as new adenosine receptor antagonists. 65
Synthesis and biological evaluation of new antitubulin agents containing 2-(30,40,50-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold 65
Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist 64
Binding affinity of adenosine receptor agonists and antagonists at human A3 adenosine receptors 64
Conjugation of Dopamine and an A2A Adenosine Receptor Antagonist: a possible approach for the treatment of Parkinson’s Disease. 64
A novel class of pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A3 adenosine receptor antagonists 63
Current developments of A(2a) adenosine receptor antagonists 63
Synthesis and pharmacological characterization of [3H]-MRE3008F20: the first radioligand antagonist for the human A3 adenosine receptors. 62
Totale 9.827
Categoria #
all - tutte 54.205
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 289
Totale 54.494


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.364 0 0 0 0 138 260 190 234 165 265 75 37
2020/20211.641 144 145 112 183 50 167 32 199 36 188 232 153
2021/20221.361 39 138 78 135 85 51 42 83 38 98 153 421
2022/20231.317 158 63 26 171 220 223 31 118 173 8 73 53
2023/2024810 70 92 34 21 71 60 20 260 12 12 10 148
2024/2025812 75 134 196 79 328 0 0 0 0 0 0 0
Totale 12.018