A review with 13 refs. The authors describe the substitution of an arom. ring with the pyridazine nucleus in the prepn. of several classes of bio-active compds. The authors described the prepn. of cardiotonics, of DNA minor groove binders such as tallimustine and anthramycin pyridazine analogs, and C-glycosides of pyridazines as antiviral agents.
Pyridazine nucleus: a pharmacophoric moiety for bio-active compounds
BARALDI, Pier Giovanni;CACCIARI, Barbara;ROMAGNOLI, Romeo;
1996
Abstract
A review with 13 refs. The authors describe the substitution of an arom. ring with the pyridazine nucleus in the prepn. of several classes of bio-active compds. The authors described the prepn. of cardiotonics, of DNA minor groove binders such as tallimustine and anthramycin pyridazine analogs, and C-glycosides of pyridazines as antiviral agents.File in questo prodotto:
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