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Multiplicity dependence of σψ(2S)/σJ/ψ in pp collisions at √s = 13 TeV

The ratio of production cross-sections of ψ(2S) over J/ψ mesons as a function of charged-particle multiplicity in proton-proton collisions at a centre-of-mass energy s = 13 TeV is measured with a data sample collected by the LHCb detector, corresponding to an integrated luminosity of 658 pb−1. The ratio is measured for both prompt and non-prompt ψ(2S) and J/ψ mesons. When there is an overlap between the rapidity ranges over which multiplicity and charmonia production are measured, a multiplic...

L’interregno dei servizi di assistenza per le persone non autosufficienti. Spunti di riflessione nella prospettiva giuslavoristica

Il saggio presenta i numerosi interventi che hanno riguardato, nell’ultimo biennio, i servizi di assistenza per le persone non autosufficienti. L’insieme degli interventi che si intreccia con le Missioni 5 e 6 del Piano nazionale per la ripresa e la resilienza (PNRR) sono letti in prospettiva giuslavoristica, attenta alle condizioni di lavoro del personale impiegato nel settore e alla centralità del welfare pubblico. Dalla breve ricostruzione operata emerge un quadro tuttora incompleto in cu...

Landscape as a Palimpsest for Energy Transition: Correlations between the Spatial Development of Energy-Production Infrastructure and Climate-Mitigation Goals

The spatial footprint of energy infrastructures requires a re-evaluation of design and planning processes, especially in relation to the sustainable development goals enshrined in the United Nations 2030 Agenda. This study investigates the Ravenna area (Italy)’s transition potential towards renewable energy sources, considering their spatial interaction with the landscape and the environment. The primary objective is to identify the opportunities and limitations associated with each type of r...

Immortalized erythroid cells as a novel frontier for in vitro blood production: current approaches and potential clinical application

Background: Blood transfusions represent common medical procedures, which provide essential supportive therapy. However, these procedures are notoriously expensive for healthcare services and not without risk. The potential threat of transfusion-related complications, such as the development of pathogenic infections and the occurring of alloimmunization events, alongside the donor's dependence, strongly limits the availability of transfusion units and represents significant concerns in transf...

Production and Characterization of K562 Cellular Clones Hyper-Expressing the Gene Encoding α-Globin: Preliminary Analysis of Biomarkers Associated with Autophagy

One of the most relevant pathophysiological hallmarks of beta-thalassemia is the accumulation of toxic alpha-globin chains inside erythroid cells, which is responsible for their premature death (hemolysis). In this context, the availability of an experimental model system mimicking the excess in alpha-globin chain production is still lacking. The objective of the present study was to produce and characterize K562 cellular clones forced to produce high amounts of alpha-globin, in order to deve...

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