SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

SIMONI, Daniele
 Distribuzione geografica
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Continente #
NA - Nord America 15.531
AS - Asia 7.352
EU - Europa 5.850
SA - Sud America 1.080
AF - Africa 154
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 12
Totale 29.991
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Nazione #
US - Stati Uniti d'America 15.249
SG - Singapore 2.702
FI - Finlandia 2.108
CN - Cina 1.943
BR - Brasile 841
DE - Germania 812
VN - Vietnam 790
UA - Ucraina 719
TR - Turchia 616
HK - Hong Kong 568
IT - Italia 564
GB - Regno Unito 481
SE - Svezia 310
FR - Francia 258
RU - Federazione Russa 193
IN - India 144
CA - Canada 139
JP - Giappone 126
PL - Polonia 113
MX - Messico 107
BD - Bangladesh 102
AR - Argentina 80
NL - Olanda 69
ZA - Sudafrica 62
ES - Italia 50
IQ - Iraq 46
PK - Pakistan 44
BE - Belgio 40
EC - Ecuador 37
ID - Indonesia 35
CL - Cile 31
CO - Colombia 30
PH - Filippine 30
MA - Marocco 29
SA - Arabia Saudita 26
LT - Lituania 25
AE - Emirati Arabi Uniti 22
PY - Paraguay 22
UZ - Uzbekistan 22
CZ - Repubblica Ceca 21
VE - Venezuela 19
MY - Malesia 16
KR - Corea 15
IE - Irlanda 13
JO - Giordania 12
IR - Iran 11
RO - Romania 11
AT - Austria 10
AU - Australia 10
CH - Svizzera 10
EG - Egitto 10
EU - Europa 9
DZ - Algeria 8
IL - Israele 8
TW - Taiwan 8
KE - Kenya 7
TH - Thailandia 7
TN - Tunisia 7
UY - Uruguay 7
AO - Angola 6
AZ - Azerbaigian 6
BH - Bahrain 6
ET - Etiopia 6
OM - Oman 6
PE - Perù 6
RS - Serbia 6
BG - Bulgaria 5
BO - Bolivia 5
JM - Giamaica 5
LB - Libano 5
NO - Norvegia 5
CR - Costa Rica 4
GT - Guatemala 4
HU - Ungheria 4
KZ - Kazakistan 4
NP - Nepal 4
PA - Panama 4
PT - Portogallo 4
SN - Senegal 4
AL - Albania 3
BY - Bielorussia 3
CI - Costa d'Avorio 3
DO - Repubblica Dominicana 3
GA - Gabon 3
GE - Georgia 3
KG - Kirghizistan 3
KH - Cambogia 3
LV - Lettonia 3
NI - Nicaragua 3
SY - Repubblica araba siriana 3
TT - Trinidad e Tobago 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BB - Barbados 2
BN - Brunei Darussalam 2
CY - Cipro 2
DM - Dominica 2
EE - Estonia 2
GR - Grecia 2
GY - Guiana 2
KW - Kuwait 2
Totale 29.957
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Città #
Helsinki 1.924
Singapore 1.785
Ashburn 1.594
Fairfield 1.464
Woodbridge 1.295
Houston 901
Dallas 887
San Jose 864
Jacksonville 775
Chandler 707
Seattle 659
Ann Arbor 631
Santa Clara 588
Beijing 563
Hong Kong 551
Wilmington 522
Cambridge 464
New York 264
Izmir 249
Ho Chi Minh City 248
Nanjing 242
Los Angeles 206
Hanoi 175
Princeton 157
Boardman 147
San Diego 139
Munich 137
Lauterbourg 128
Tokyo 114
Addison 102
The Dalles 99
Warsaw 92
Shanghai 87
São Paulo 87
Shenyang 77
London 75
Milan 72
Mexico City 71
Nanchang 71
Chicago 64
Hefei 63
Tianjin 61
Ferrara 59
Changsha 57
Hebei 57
Orem 55
Dong Ket 54
San Mateo 54
Frankfurt am Main 47
Jinan 42
Montreal 42
Bremen 41
Chennai 41
Haiphong 40
Turku 40
Brussels 39
Brooklyn 38
San Francisco 37
Amsterdam 35
Da Nang 35
Falkenstein 35
Atlanta 34
Buffalo 33
Jiaxing 33
Moscow 33
Denver 32
Falls Church 32
Philadelphia 31
Bologna 30
Boston 29
Rio de Janeiro 29
Toronto 29
Guangzhou 28
Phoenix 26
Johannesburg 25
Verona 25
Baghdad 24
Auburn Hills 21
Council Bluffs 21
Norwalk 21
Tashkent 20
Belo Horizonte 19
Mountain View 19
Poplar 19
Stockholm 19
Brasília 18
Manchester 18
Mumbai 18
Washington 18
Zhengzhou 18
Hangzhou 17
Jakarta 17
Kunming 17
Dearborn 16
Quito 16
Redwood City 16
Rome 16
Biên Hòa 15
Mcallen 15
Salt Lake City 15
Totale 21.131
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Nome #
1,2,4-triazoles. Improved synthesis of 5-substituited 4-amino-3mercato-(4H)-1,2,4 triazoles and a facile route to 3,6-disubstituited 1,24-triazolo[3,4b][1,3,4]thiadiazoles 3.009
1,5,7-Triazabicyclo[4.4.0]dec-1-ene (TBD), 7-methyl-TBD (MTBD) and the polymer-supported TBD (P-TBD): Three efficient catalysts for the nitroaldol (Henry) reaction and for the addition of dialkyl phosphites to unsaturated systems 334
4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors 291
A facile, efficient synthesis of 2-substituted-4-hydroxy-2-cyclopenten-1-ones 290
A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approach 288
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 281
A [3+2] nitrile oxide intermolecular cycloaddition approach to 4,5-dihydro-3(2H)-furanone and 3(2H)-furanone ring systems: application to the formal synthesis of (±)-ascofuranone and geiparvarin. 279
Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitor 271
3,5-Disubstituted isoxazoles as a latent aldol moiety: Application to the synthesis of (±)-[6]-gingerol 268
Retinoic acid conjugates as potential antitumor agents: Synthesis and biological activity of conjugates with Ara-A, Ara-C, 3(2H)-furanone, and aniline mustard moieties 268
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors 268
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 264
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 263
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 256
A [3 + 2] nitrile oxide cycloaddition approach to retinoids 253
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity 246
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 245
A new nitrile oxide based synthesis of the antitumor agent geiparvarin 244
3,5-Disubstituted Isoxazoles as Synthons for (±)-Pyrenophorin and (±)-Vermiculine Synthesis 244
Design, synthesis and biological evaluation of novel stilbene-based antitumor agents 244
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 240
Novel terphenyls and 3,5-diaryl isoxazole derivatives endowed with growth supporting and antiapoptotic properties 240
Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer 238
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 230
Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth 229
A new direct glycosylation of pyrimidine, pyrazole, imidazole and purine heterocycles via their N-tetrahydropyranyl (THP) derivatives 229
Development of water soluble derivatives of cis-3, 4', 5-trimethoxy-3'- aminostilbene for optimization and use in cancer therapy 224
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 221
Geiparvarin analogs. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates. 219
A one-pot glycosylation of tetrahydropyranyl (THP) ether intermediates 218
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 215
Ethyl 2,4-dioxoalkanoates as starting materials for a convenient route to 3(2H)-furanones and 3(2H)-furanimines 214
Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death 214
Methyl 4-oxothiolane-3-carboxylate and methyl 2-methyl-4-oxothiolane-3- carboxylate anions as synthetic equivalents of α-acrylate and α-crotonate anions. Formal synthesis of integerrinecic acid 213
Studies on the apoptotic activity of natural and synthetic retinoids: Discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells 213
Novel combretastatin analogues endowed with antitumor activity 212
Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents 210
Synthesis of 8-oxa analogues of norcocaine endowed with interesting cocaine-like activity 209
Antitumor effects of curcumin and structurally β-diketone modified analogs on multidrug resistant cancer cells 209
The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: Analysis of the possible molecular basis 208
Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities 204
Cyclic guanidines: Synthesis of 4,6,7,8‐tetrahydro‐1H‐imidazo[1,2‐a]pyrazolo[3,4‐d]pyrimidin‐7‐ones and 1,4,6,7,8,9‐hexahydropyrazolo[3′,4′:4,5]pyrimido[2,1‐c] [1,2,4]triazin‐7‐ones 203
Preparation of 3,4-dihydroxy-1-benzeneethanol: a reinvestigation 202
Geiparvarin Analogs. 4.1. Synthesis and Cytostatic Activity of Geiparvarin Analogs Bearing a Carbamate Moiety or a Furocoumarin Fragment on the Alkenyl Side Chain 199
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells. 199
Synthesis of syn- and anti-tricyclo [4.1.0.02,4] heptan-5-ones and related compounds 197
Geiparvarin Analogs. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain 197
Derivati isossazolici come induttori di emoglobina fetale in precursori eritroidi derivati da pazienti beta-talassemici 196
Synthesis and cytotoxic activity of 6-vinyl- and 6-ethynyluridine and 8-vinyl- and 8-ethynyladenosine 195
Antitumor effects of new synthetic isoxazole derivatives 193
Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a γδ-T lymphocytes-mediated activation mechanism 192
A practical entry to C18-constrained-E-ring analogues of methyllycaconitine (MLA): a concise new stereoselective approach to 8-oxa-decahydrolsoquinolines accompanied by a simple microwaves-assisted synthesis of the succinimidobenzoate appendage of MLA 192
Aryl and Heterocyclic Derivatives of Combretastatin A-4 Endowed with Anticancer Properties 190
5-Phenyl-isoxazole-3-carboxamides modulating Hsp90 with antitumoral activities 189
A PLE-based resolution of cocaine, pseudococaine and 6-and 7-methoxylated cocaine analogues 187
Enantioselective deprotonation of the 8-oxabicyclo[3.2.1]octan-3-one: Synthesis of 8-oxa-norcocaines and 8-oxa-pseudonorcocaines 186
Strong Bicyclic Guanidine Base-promoted Wittig and Horner-Wadsworth-Emmons Reactions 185
Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells. 184
Synthesis of 2-(5-substituted isoxazol-3-yl)-4-oxo-3-thiazolidinyl alkanoic acids 183
Analoghi eterociclici dell’acido retinoico (eteroretinoidi) come potenziali agenti “anti-aging”. 183
3,6-Disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: synthesis and evaluation for antimicrobial and antiviral activity. III. 182
Sintesi di derivati pirazolici e pirazolo[4,3-d]pirimidonici. Nota II 182
L’1,2-Dimetil-4-ossimino-3,5-pirazolidindione come attivatore nella sintesi peptidica 179
Concise enantioselective synthesis and attribution of the absolute configuration of two-carbon bridge methoxylated cocaines and pseudococaines 179
Synthesis of 6‐substituted‐4,5‐dihydro‐3(2H)‐pyridazinones 178
Cis-3, 4′, 5-Trimethoxy-3′-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion 178
Total Synthesis of (±) isoclovene 175
Synthesis and reactivity of a stable precursor of 2-cyano-1,3-butadiene 174
Two-carbon bridge substituted cocaines: Enantioselective synthesis, attribution of the absolute configuration and biological activity of novel 6- and 7-methoxylated cocaines 173
5-Phenyl-isoxazole-3-carboxamides modulating HSP90 with antitumoral activities 173
A novel α-acrylate anion equivalent: A useful synthon for α-substituted acrylic esters 172
Facile synthesis of 2-nitroalkanols by Tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones 172
Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells 172
Isoxazole-mediated synthesis of geiparvarin and dihydrogeiparvarin 171
Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c]pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists 171
Synthesis of natural products via isoxazoles 170
Pig liver esterase (PLE)-mediated resolution of N-substituted 4-benzoyloxy-3-carbomethoxypiperidines: a convenient preparation of 4-hydroxy- and 4-benzoyloxy-3-carbomethoxypiperidines in enantiomerically pure form 170
Facile synthesis of pyrazoles and pyrroles via thermolysis of tetrazolo[1,5-b]pyridazines, tetrazolo[1,5-a]pyrimidines and tetrazolo[1,5-a]pyridines 170
Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells 169
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis 169
Synthesis and Prostaglandin-like Activity of 2-(trans-3-Hydroxy-1-octenyl)-3-indolheptanoic Acid 169
Sintesi di derivati pirazolici e pirazolo[4,3-d]pirimidonici. Nota I 168
New synthetic isoxazole derivatives as potent inducer of fetal hemoglobin (HbF) in beta-thalassemia 168
Pyrazole-Related Nucleosides. Synthesis and Antiviral/Antitumor Activity of Some Substituted Pyrazole and Pyrazolo[4,3-d]-1,2,3-triazin-4-one Nucleosides 166
Stereoselective synthesis of 8-aza-9,11-ethenoprostaglandin H1 166
Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs) 166
Synthesis of 1-phenyl-substituted 3-methyl-1H-pyrazolo[3,4-b]pyrazine-5,6-dicarboxylic acid diethyl esters. 164
Versatile Synthesis of New Cytotoxic Agents Structurally Related to Emiasterlins 163
Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro 162
Regio - and enantioselective bioreduction of ethyl 2,4-dioxoalkanoates and γ-Keto-α-enamino esters with fermenting baker's yeast 160
Ethyl 5-substituted-3-isoxazole carboxvyates as starting materials for a convenient route to 3(2H )-furanones and 3(2H )-iminofuranes 158
Brain receptor binding of analogues of gamma-aminobutyric acid (GABA) 158
Mechanism of cell death induced by cis-3, 4′, 5-trimethoxy-3′-aminostilbene in ovarian cancer 157
Facile access to 2'-O-acyl prodrugs of 1-(β-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil (BVAraU) via regioselective esterase-catalyzed hydrolysis of 2',3',5'-triesters 156
Synthesis of an 11-Deoxy-8-azaprostaglandin E1 Intermediate 156
The synergistic apoptotic effects of thiophenfurin, an inosine monophosphate dehydrogenase inhibitor, in combination with retinoids in HL60 cells 155
Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines 155
Asymmetric synthesis of a β-ketol moiety via 3,5-disubstituted isoxazoles: Application to (+)-(S)-[6]-gingerol 153
Elaboration of the ωChain of 11 -Deoxyprostanoid Derivatives through Isoxazole Intermediates 152
Stilbene-based anticancer agents: Resveratrol analogues active toward HL60 leukemic cells wit a non-specific phase mechanism 152
Totale 23.050
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Categoria #
all - tutte 121.178
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 687
Totale 121.865
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021201 0 0 0 0 0 0 0 0 0 0 0 201
2021/20221.798 67 126 127 106 184 86 71 82 84 93 161 611
2022/20231.649 166 107 57 203 301 254 40 157 211 12 82 59
2023/2024877 91 98 64 22 56 194 40 59 15 26 28 184
2024/20253.170 130 78 289 117 412 225 69 196 428 348 532 346
2025/202612.096 989 555 1.308 1.236 1.440 735 1.124 491 2.691 1.085 341 101
Totale 30.172