BOREA, Pier Andrea
 Distribuzione geografica
Continente #
NA - Nord America 55.075
AS - Asia 29.881
EU - Europa 20.477
SA - Sud America 4.476
Continente sconosciuto - Info sul continente non disponibili 676
AF - Africa 616
OC - Oceania 55
Totale 111.256
Nazione #
US - Stati Uniti d'America 53.823
SG - Singapore 10.659
CN - Cina 7.840
IT - Italia 3.910
DE - Germania 3.709
BR - Brasile 3.442
VN - Vietnam 3.189
FI - Finlandia 3.105
UA - Ucraina 3.090
HK - Hong Kong 2.505
TR - Turchia 2.383
GB - Regno Unito 1.733
SE - Svezia 1.224
FR - Francia 1.139
RU - Federazione Russa 922
JP - Giappone 644
BD - Bangladesh 632
IN - India 606
CA - Canada 587
PL - Polonia 469
MX - Messico 441
AR - Argentina 384
NL - Olanda 307
ZA - Sudafrica 236
ID - Indonesia 232
IQ - Iraq 195
ES - Italia 180
EC - Ecuador 159
CO - Colombia 150
BE - Belgio 144
PK - Pakistan 126
VE - Venezuela 108
UZ - Uzbekistan 98
LT - Lituania 94
SA - Arabia Saudita 87
CZ - Repubblica Ceca 84
MA - Marocco 84
CL - Cile 83
MY - Malesia 83
PH - Filippine 81
TN - Tunisia 78
AT - Austria 75
AE - Emirati Arabi Uniti 73
PY - Paraguay 63
KE - Kenya 50
JO - Giordania 45
AU - Australia 44
JM - Giamaica 42
EG - Egitto 41
CR - Costa Rica 40
IR - Iran 40
IE - Irlanda 37
KR - Corea 37
IL - Israele 36
NP - Nepal 31
RO - Romania 30
DZ - Algeria 29
HN - Honduras 28
TW - Taiwan 28
UY - Uruguay 28
PE - Perù 27
AZ - Azerbaigian 25
PT - Portogallo 25
BO - Bolivia 24
AL - Albania 23
CH - Svizzera 22
KZ - Kazakistan 22
EU - Europa 21
TH - Thailandia 21
ET - Etiopia 20
PS - Palestinian Territory 20
OM - Oman 18
BG - Bulgaria 17
LB - Libano 16
RS - Serbia 15
SN - Senegal 15
TT - Trinidad e Tobago 15
GT - Guatemala 14
KG - Kirghizistan 14
SV - El Salvador 14
BH - Bahrain 13
DO - Repubblica Dominicana 13
PA - Panama 13
QA - Qatar 13
SY - Repubblica araba siriana 13
GR - Grecia 11
HU - Ungheria 11
LV - Lettonia 11
MD - Moldavia 11
NO - Norvegia 11
BY - Bielorussia 10
HR - Croazia 10
NI - Nicaragua 10
AM - Armenia 9
BA - Bosnia-Erzegovina 9
NZ - Nuova Zelanda 9
AO - Angola 8
CI - Costa d'Avorio 8
KH - Cambogia 8
SK - Slovacchia (Repubblica Slovacca) 8
Totale 110.439
Città #
Singapore 6.957
Ashburn 5.374
Woodbridge 4.580
Fairfield 3.675
San Jose 3.485
Jacksonville 3.305
Chandler 2.911
Houston 2.898
Hong Kong 2.454
Ann Arbor 2.405
Santa Clara 2.325
Helsinki 2.277
Beijing 2.241
Wilmington 1.662
Dallas 1.567
Seattle 1.556
Council Bluffs 1.525
Cambridge 1.158
Izmir 1.123
Ho Chi Minh City 1.072
Nanjing 1.020
Los Angeles 881
Hanoi 773
Princeton 714
New York 639
Tokyo 623
Lauterbourg 559
Boardman 530
Munich 527
Milan 488
Ferrara 462
Warsaw 403
San Diego 351
São Paulo 327
Nanchang 324
Shanghai 319
Shenyang 306
Falkenstein 290
Mexico City 273
Hefei 243
Orem 231
Tianjin 221
London 209
Hebei 204
Dearborn 203
Turku 194
Buffalo 189
Changsha 189
Chicago 188
Bremen 183
Frankfurt am Main 176
San Mateo 176
Addison 170
Jiaxing 169
The Dalles 169
Toronto 168
Rome 157
Da Nang 155
Montreal 155
Brooklyn 150
Chennai 144
Brussels 138
Denver 130
Jinan 128
Haiphong 127
Phoenix 121
Atlanta 120
San Francisco 119
Amsterdam 117
Johannesburg 117
Jakarta 116
Falls Church 115
Rio de Janeiro 112
Zhengzhou 112
Manchester 102
Moscow 101
Kunming 99
Guangzhou 98
Norwalk 95
Auburn Hills 94
Bologna 92
Philadelphia 91
Stockholm 90
Tashkent 88
Florence 87
Mountain View 85
Baghdad 80
Ningbo 80
Boston 78
Poplar 78
Mumbai 73
Belo Horizonte 67
Ankara 64
Biên Hòa 63
Düsseldorf 63
Orange 63
Redwood City 63
Naples 62
Quito 59
Hải Dương 58
Totale 72.047
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.112
Farmacologia cellulare e molecolare, sistemi di trasmissione e autacoidi. Trasmissione purinergica 1.445
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 424
Pharmacology of Adenosine Receptors: The State of the Art 420
Progetto ex 60%- I recettori dell’adenosina come possibili “biomarkers” dei tumori colorettali. Studio su tessuti umani sani e tumorali e sulle cellule del sangue periferico. 407
Dose and time effects of caffeine intake on human platelet adenosine A2A receptors: functional and biochemical aspects 349
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists 343
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 330
Caffeine alters A(2A) adenosine receptors and their function in human platelets 330
A glance at adenosine receptors: Novel target for antitumor therapy 320
Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists 315
Alterazioni dei recettori alfa(2) adrenergici delle piastrine umane nell'ipertensione essenziale 310
Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48. Behavioural, neurochemical and Dopamine transporter scan imaging studies in mice 309
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 304
Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 298
The A3 adenosine receptor: history and perspectives 294
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine (medazepam) 292
A(2B) adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway 291
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 290
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 284
2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation 280
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects? 277
Recettori e trasduzione del segnale 276
Pulsed Electromagnetic Field Exposure Reduces Hypoxia and Inflammation Damage in Neuron-Like and Microglial Cells 269
Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields 267
A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release 267
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease 266
Human vascular kinin receptors of the B-2 type characterized by radioligand binding 265
Recettori e trasduzione del segnale 264
Adenosine receptors and human melanoma 263
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 259
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 258
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts 257
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 257
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 250
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter 249
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 249
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 248
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 248
Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils. 248
Role and function of A2A and A3 adenosine receptors in patients with ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis 246
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 245
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes. 245
A(2A) adenosine receptors are up-regulated in lymphocytes from amyotrophic lateral sclerosis patients 245
Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells 244
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 243
Ala scan analogues of HOE 140. Synthesis and biological activities 243
Comparison of prazosin, terazosin and tamsulosin: Functional and binding studies in isolated prostatic and vascular human tissues 241
Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies 241
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy 241
Multiple sclerosis lymphocytes upregulate A(2A) adenosine receptors that are antiinflammatory when stimulated 240
Alteration of A3 adenosine receptors in human neutrophils and low frequency electromagnetic fields 239
Cannabinoid CB2 receptor attenuates morphine-induced inflammatory responses in activated microglial cells 237
5-heteroarylcarbamoylamino-pyrazolo-triazolo pyrimidines as hA3 adenosine receptor antagonists. 236
2 Aralkynyl and 2-heteroalkynyl derivatives of adenosine 5'-N-ethyluronamide as selective A2A adenosine receptor agonists 235
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 235
Octadecyl, phenyl and cyano phases comparison for the RP-HPLC prediction of octanol-water partition coefficient 233
Adenosine signaling contributes to ethanol-induced fatty liver in mice 232
Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells. 232
7-nitro-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one (nitrazepam) 232
Adenosine receptors and cancer 231
HIF-1 neuroprotection through erythropoietin increase in hypoxia: a role for A1 adenosine receptors 230
The activation of μ-opioid receptor potentiates LPS-induced NF-kB promoting an inflammatory phenotype in microglia 230
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility 229
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 228
A3 Receptors are Overexpressed in Pleura from Mesothelioma Patients and Reduce Cell Growth via Akt/NF-kB Pathway. 228
Adenosine receptor targeting in health and disease 228
4-(4-Fluorobenzoyl)-1-[2-(4-iodo-2,5-dimethoxyphenyl)ethyl]piperidine and its derivatives: Synthesis and affinity at 5-HT(2A), 5-HT(2B) and 5- HT(2C) serotonin receptors 227
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 226
ALTERATION OF ADENOSINE RECEPTORS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE 226
Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity 226
Current status of A1 adenosine receptor allosteric enhancers 225
Binding thermodynamics and intrinsic activity of adenosine A1 receptor ligands 224
A concerted binding study using binding measurements, X-ray structural data and molecular modeling on the stereochemical features responsible for the affinity of 6-arylpyrrolo[2,1-d][1,5]benzothiazepines to mitochondrial benzodiazepine receptors 224
Alteration of adenosine receptore in patients with chronic obstructive pulmonary disease 224
A3 adenosine receptors are overexpressed in pleura from patients with mesothelioma and reduce malignant mesothelioma cell growth 223
[3H]-MRE 2029-F20, a novel selective antagonist radioligand, for the pharmacological and biochemical characterization of A2B receptors. 223
van't Hoff Based Thermodynamics 223
The Anti-Tumor Effect of A(3) Adenosine Receptors Is Potentiated by Pulsed Electromagnetic Fields in Cultured Neural Cancer Cells 222
A3 adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study 222
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 222
Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension 221
A2A adenosine receptor upregulation correlates with disease activity in patients with systemic lupus erythematosus 221
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 221
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor 220
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells 219
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 219
Synthesis and pharmacology of 6-substituted benztropines: Discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter 219
Pathological overproduction: the bad side of adenosine 219
P2X1 and P2X3 Purinergic Receptors Differentially Modulate the Inflammatory Response in Human Osteoarthritic Synovial Fibroblasts 218
3H SCH 58261 labelling of functional A2A adenosine receptors in human neutrophil membranes 218
Binding and signaling studies disclose a potential allosteric site for cannabidiol in cannabinoid CB2 receptors 218
Targeting A3 and A2A adenosine receptors in the fight against cancer 218
M3 muscarinic receptors in peripheral lung parenchima of patients with chronic obstructive pulmonary disease. 217
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 217
Agonists and antagonists: Molecular mechanisms and therapeutic applications 217
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 216
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 216
Adenosine Receptors as a Biological Pathway for the Anti-Inflammatory and Beneficial Effects of Low Frequency Low Energy Pulsed Electromagnetic Fields 216
Electrophysiological basis for the enhanced cardiac arrhythmogenic effect of isoprenaline in aged spontaneously hypertensive rats 215
Totale 29.355
Categoria #
all - tutte 469.377
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 17.949
Totale 487.326


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20226.264 0 667 443 343 406 252 229 321 245 500 823 2.035
2022/20236.799 720 418 200 898 1.133 1.042 273 566 876 53 372 248
2023/20243.370 354 442 175 97 353 386 183 242 66 101 107 864
2024/202513.457 395 383 1.062 633 1.646 1.192 406 904 1.847 1.522 1.911 1.556
2025/202640.756 3.833 1.684 3.942 4.949 5.365 2.610 4.561 1.952 5.516 4.244 1.388 712
2026/20273.338 1.290 2.048 0 0 0 0 0 0 0 0 0 0
Totale 111.256