PRETI, Delia
 Distribuzione geografica
Continente #
NA - Nord America 13.715
EU - Europa 8.313
AS - Asia 6.665
SA - Sud America 1.248
AF - Africa 158
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 7
Totale 30.113
Nazione #
US - Stati Uniti d'America 13.430
FI - Finlandia 4.008
SG - Singapore 2.289
CN - Cina 1.744
DE - Germania 1.400
BR - Brasile 981
VN - Vietnam 843
IT - Italia 772
HK - Hong Kong 561
UA - Ucraina 507
TR - Turchia 427
GB - Regno Unito 423
RU - Federazione Russa 357
FR - Francia 229
SE - Svezia 214
CA - Canada 147
JP - Giappone 143
IN - India 139
PL - Polonia 118
BD - Bangladesh 115
AR - Argentina 109
MX - Messico 104
ID - Indonesia 83
ZA - Sudafrica 67
IQ - Iraq 58
NL - Olanda 55
PK - Pakistan 47
ES - Italia 46
BE - Belgio 45
EC - Ecuador 34
CO - Colombia 32
UZ - Uzbekistan 27
SA - Arabia Saudita 22
MA - Marocco 21
CL - Cile 20
VE - Venezuela 20
KR - Corea 19
LT - Lituania 19
CZ - Repubblica Ceca 18
IL - Israele 18
MY - Malesia 17
UY - Uruguay 17
PY - Paraguay 16
AT - Austria 15
IE - Irlanda 15
KE - Kenya 15
PE - Perù 14
PH - Filippine 14
TN - Tunisia 13
EG - Egitto 12
AE - Emirati Arabi Uniti 11
JO - Giordania 10
KZ - Kazakistan 10
PT - Portogallo 10
SK - Slovacchia (Repubblica Slovacca) 10
DZ - Algeria 9
TH - Thailandia 9
AZ - Azerbaigian 8
NP - Nepal 8
TW - Taiwan 8
JM - Giamaica 7
CR - Costa Rica 6
EU - Europa 6
AL - Albania 5
AU - Australia 5
BO - Bolivia 5
GR - Grecia 5
HR - Croazia 5
IR - Iran 5
LV - Lettonia 5
MD - Moldavia 5
AO - Angola 4
KG - Kirghizistan 4
PS - Palestinian Territory 4
RS - Serbia 4
BG - Bulgaria 3
BH - Bahrain 3
CH - Svizzera 3
GA - Gabon 3
GH - Ghana 3
GT - Guatemala 3
HU - Ungheria 3
NI - Nicaragua 3
OM - Oman 3
PA - Panama 3
QA - Qatar 3
BA - Bosnia-Erzegovina 2
BY - Bielorussia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
HN - Honduras 2
KH - Cambogia 2
LB - Libano 2
MN - Mongolia 2
RO - Romania 2
SV - El Salvador 2
TJ - Tagikistan 2
TT - Trinidad e Tobago 2
AM - Armenia 1
Totale 30.087
Città #
Helsinki 3.819
Dallas 1.746
Singapore 1.508
Ashburn 1.397
Fairfield 1.101
Woodbridge 1.036
San Jose 851
Ann Arbor 606
Houston 557
Beijing 553
Hong Kong 536
Jacksonville 533
Santa Clara 506
Chandler 500
Seattle 436
Wilmington 402
Cambridge 338
Ferrara 288
Ho Chi Minh City 250
Munich 204
New York 196
Hanoi 193
Izmir 184
Los Angeles 181
Nanjing 154
Princeton 131
Tokyo 131
Boardman 121
Lauterbourg 112
San Diego 111
Shanghai 110
Warsaw 103
Council Bluffs 95
São Paulo 93
Milan 85
Turku 76
Dong Ket 64
Orem 64
Mexico City 61
Bremen 57
Montreal 55
London 54
Bologna 52
Hefei 51
Nanchang 50
Shenyang 50
Tianjin 49
Chicago 48
Frankfurt am Main 48
Brussels 45
Jakarta 45
Atlanta 44
Brooklyn 43
Falkenstein 40
Rio de Janeiro 39
Johannesburg 38
Phoenix 38
Chennai 37
Changsha 36
Dearborn 35
Toronto 35
Da Nang 34
Denver 33
San Mateo 32
Buffalo 30
Hebei 30
Poplar 29
Falls Church 27
Jiaxing 27
Redwood City 27
Amsterdam 26
Boston 26
Guangzhou 26
Haiphong 26
Moscow 26
Mountain View 25
Tashkent 24
Baghdad 23
Brasília 23
San Francisco 23
Stockholm 23
Ankara 22
Belo Horizonte 22
Manchester 21
Philadelphia 21
Washington 21
Addison 20
Rome 20
Zhengzhou 20
Mumbai 19
The Dalles 19
Curitiba 18
Hải Dương 16
Jinan 16
Kunming 16
Biên Hòa 15
Columbus 15
Dublin 15
Nuremberg 15
Auburn Hills 14
Totale 21.306
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.095
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 2.940
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 319
A3 adenosine receptor antagonists: History and future perspectives 286
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 276
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 263
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 262
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 253
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 250
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 244
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 243
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 243
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 241
DNA minor groove binders as potential antitumor and antimicrobial agents 241
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 240
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 240
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 239
Allosteric enhancers for A(1) adenosine receptor 236
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 236
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 231
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 229
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 228
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 226
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 225
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 224
Hybrid molecules between distamycin A and active moieties of antitumor agents 222
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 221
Hybrid molecules based on distamycin A as potential antitumor agents 219
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 216
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 214
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 213
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 212
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 212
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 210
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 210
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 209
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 209
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 209
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 209
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 207
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 205
Neuropeptide S receptor ligands: a patent review (2005-2016) 205
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 204
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 204
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 203
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 203
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 202
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 202
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 199
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 197
Recent developments in the field of adenosine receptor ligands. 196
Recent improvements in the development of A2B adenosine receptor agonists 196
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 195
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 193
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 193
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 192
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 192
Adenosine modulates HIF-1, VEGF, IL-8 and foam cells formation in a human model of hypoxic foam cells 191
Adenosine in a human model of Hypoxic foam cells 190
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 190
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 189
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 188
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 188
New strategies for the synthesis of A(3) adenosine receptor antagonists 186
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 185
alpha-Halogenoacrylic Derivatives of Antitumor Agents 185
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system 180
Adenosine modulates HIF-1α, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells 179
Ozone-induced hypertussive responses in rabbits and guinea pigs 179
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 179
Recent improvements in the development of A2B adenosine receptor agonists 178
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 176
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 174
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice 174
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 173
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 172
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 171
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 171
Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors 167
Recent improvements in the field of A(3) adenosine receptor ligands 166
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 165
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 164
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 163
Novel Mixed NOP/Opioid Receptor Peptide Agonists 163
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 161
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 160
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 159
The P2X7 receptor as a therapeutic target 158
TRP channels as therapeutic targets in airway disorders: a patent review 157
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 156
COMPOSTI 1,3,8-TRIAZASPIRO E LORO USO COME MEDICAMENTI 156
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 156
Ligands for A(2B) adenosine receptor subtype 155
New pyrrolo [2,1-f] purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione derivates as potent and selective human A3 adenosine receptor antagonists 152
Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase 142
COMPOSTI SOLFONAMMIDICI COME INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO COME MEDICAMENTI 138
Novel 1,3-Dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as Potent and Selective A2B Adenosine Receptor Antagonists 138
Compounds as nlrp3 inflammasome inhibitors and their use as medicaments 137
Recent developments in the field of A2B and A3 adenosine receptors antagonists 137
Medicinal chemistry of the a(3) adenosine receptor: agonists, antagonists, and receptor engineering 134
Totale 25.465
Categoria #
all - tutte 105.667
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.479
Totale 108.146


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021168 0 0 0 0 0 0 0 0 0 0 0 168
2021/20221.365 62 127 137 55 88 61 84 57 47 105 140 402
2022/20231.270 132 86 23 181 239 171 53 92 169 9 64 51
2023/2024831 59 96 49 25 60 137 41 90 25 19 22 208
2024/20253.344 85 99 271 144 350 322 103 194 474 348 494 460
2025/202614.833 975 962 2.043 1.139 1.350 682 1.077 514 4.551 1.135 402 3
Totale 30.327