PRETI, Delia
 Distribuzione geografica
Continente #
NA - Nord America 7.651
EU - Europa 2.933
AS - Asia 1.432
SA - Sud America 12
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 3
AF - Africa 2
Totale 12.039
Nazione #
US - Stati Uniti d'America 7.640
DE - Germania 1.077
CN - Cina 781
UA - Ucraina 474
IT - Italia 439
TR - Turchia 375
GB - Regno Unito 264
RU - Federazione Russa 220
SE - Svezia 187
SG - Singapore 146
FI - Finlandia 111
VN - Vietnam 66
PL - Polonia 58
BE - Belgio 35
FR - Francia 23
HK - Hong Kong 16
ID - Indonesia 15
NL - Olanda 14
CZ - Repubblica Ceca 11
CA - Canada 10
IN - India 9
KR - Corea 9
EU - Europa 6
BR - Brasile 4
CL - Cile 4
IL - Israele 4
AR - Argentina 3
AU - Australia 3
ES - Italia 3
IR - Iran 3
JP - Giappone 3
LT - Lituania 3
PK - Pakistan 3
IE - Irlanda 2
PT - Portogallo 2
AT - Austria 1
BG - Bulgaria 1
CH - Svizzera 1
DK - Danimarca 1
EG - Egitto 1
GR - Grecia 1
HR - Croazia 1
KH - Cambogia 1
MA - Marocco 1
MC - Monaco 1
MN - Mongolia 1
MX - Messico 1
PE - Perù 1
RO - Romania 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 12.039
Città #
Fairfield 1.100
Woodbridge 1.035
Ann Arbor 606
Ashburn 574
Houston 534
Jacksonville 531
Chandler 500
Seattle 422
Wilmington 401
Cambridge 338
Ferrara 199
Izmir 182
Beijing 177
Nanjing 152
Princeton 131
Boardman 120
San Diego 108
Shanghai 97
Singapore 92
Milan 67
Dong Ket 64
Warsaw 58
Bremen 57
Nanchang 50
Shenyang 49
New York 41
Tianjin 36
Brussels 35
Dearborn 35
San Mateo 32
Changsha 31
Hebei 30
Falls Church 27
Jiaxing 27
Redwood City 27
Mountain View 25
London 21
Addison 20
Philadelphia 18
Zhengzhou 18
Washington 17
Kunming 16
Jinan 15
Auburn Hills 14
Hong Kong 14
Jakarta 14
Munich 14
Duncan 13
Indiana 13
Helsinki 12
Norwalk 12
Orange 12
Des Moines 11
Ferrara di Monte Baldo 11
Los Angeles 11
Guangzhou 10
Tappahannock 10
Amsterdam 9
Bari 8
Brno 8
Kilburn 8
Mcallen 8
Montréal 8
Ningbo 7
Padova 7
Verona 7
Chicago 6
Haikou 6
Hangzhou 6
Lanzhou 6
Rome 6
Bologna 5
Prescot 5
Augusta 4
Düsseldorf 4
Grassano 4
Naples 4
West Jordan 4
Xian 4
Yellow Springs 4
Bournemouth 3
Chongqing 3
Florence 3
Frankfurt am Main 3
Leawood 3
Lugo 3
Mysore 3
Olomouc 3
Taizhou 3
Tel Aviv 3
Waban 3
Wandsworth 3
Aversa 2
Buenos Aires 2
Calvizzano 2
Dublin 2
Hanoi 2
Hefei 2
Hyderabad 2
Isola della Scala 2
Totale 8.476
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 314
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 161
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 141
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 138
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 138
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 137
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 133
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 133
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 133
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 132
DNA minor groove binders as potential antitumor and antimicrobial agents 131
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 131
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 131
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 130
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 130
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 129
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 129
Hybrid molecules based on distamycin A as potential antitumor agents 128
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 127
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 125
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 125
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 124
null 124
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 124
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 123
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 122
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 122
Recent improvements in the development of A2B adenosine receptor agonists. 121
null 121
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 120
A3 adenosine receptor antagonists: History and future perspectives 120
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 120
null 120
null 118
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 115
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 114
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 113
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 113
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 113
Allosteric enhancers for A(1) adenosine receptor 112
null 112
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 112
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 112
Hybrid molecules between distamycin A and active moieties of antitumor agents 112
Recent improvements in the development of A2B adenosine receptor agonists 111
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 111
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 111
null 110
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 110
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 110
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists. 109
null 109
Ozone-induced hypertussive responses in rabbits and guinea pigs 107
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 105
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 104
Neuropeptide S receptor ligands: a patent review (2005-2016) 104
null 103
The P2X7 receptor as a therapeutic target. 102
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 102
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 100
Recent developments in the field of adenosine receptor ligands. 100
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 100
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 99
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. 99
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 99
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 98
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked heterocycles as template for the adenosine receptor antagonism: medicinal chemistry approach and SAR considerations. 97
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 97
null 96
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 95
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 95
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 92
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 92
null 92
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 92
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 91
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 91
New strategies for the synthesis of A(3) adenosine receptor antagonists 89
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 88
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 88
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 87
null 87
null 87
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 86
TRP channels as therapeutic targets in airway disorders: a patent review 86
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 84
null 84
null 83
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 83
null 82
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 82
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 81
Recent developments in the field of A2B and A3 adenosine receptors antagonists 80
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 79
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 79
Adenosine Modulates HIF-1 alpha, VEGF, IL-8, and Foam Cell Formation in a Human Model of Hypoxic Foam Cells 78
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 78
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice 76
Recent improvements in the field of A(3) adenosine receptor ligands 75
Ligands for A(2B) adenosine receptor subtype 74
Totale 10.912
Categoria #
all - tutte 46.555
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.205
Totale 47.760


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.469 378 94 83 356 180 285 226 240 208 231 141 47
2020/20211.854 183 134 91 184 85 183 83 217 59 281 186 168
2021/20221.365 62 127 137 55 88 61 84 57 47 105 140 402
2022/20231.270 132 86 23 181 239 171 53 92 169 9 64 51
2023/2024831 59 96 49 25 60 137 41 90 25 19 22 208
2024/202570 70 0 0 0 0 0 0 0 0 0 0 0
Totale 12.220