PRETI, Delia
 Distribuzione geografica
Continente #
NA - Nord America 14.313
EU - Europa 8.465
AS - Asia 6.789
SA - Sud America 1.254
Continente sconosciuto - Info sul continente non disponibili 221
AF - Africa 160
OC - Oceania 9
Totale 31.211
Nazione #
US - Stati Uniti d'America 13.971
FI - Finlandia 4.008
SG - Singapore 2.326
CN - Cina 1.770
DE - Germania 1.402
BR - Brasile 984
IT - Italia 870
VN - Vietnam 843
HK - Hong Kong 572
UA - Ucraina 507
TR - Turchia 428
GB - Regno Unito 423
RU - Federazione Russa 357
SE - Svezia 253
FR - Francia 233
CA - Canada 175
BD - Bangladesh 156
JP - Giappone 143
IN - India 141
PL - Polonia 119
AR - Argentina 109
MX - Messico 105
ID - Indonesia 83
ZA - Sudafrica 67
IQ - Iraq 58
NL - Olanda 58
ES - Italia 50
PK - Pakistan 47
BE - Belgio 45
EC - Ecuador 34
CO - Colombia 33
UZ - Uzbekistan 27
SA - Arabia Saudita 22
CL - Cile 21
MA - Marocco 21
VE - Venezuela 21
KR - Corea 19
LT - Lituania 19
MY - Malesia 19
CZ - Repubblica Ceca 18
IL - Israele 18
UY - Uruguay 17
JM - Giamaica 16
PY - Paraguay 16
AT - Austria 15
IE - Irlanda 15
KE - Kenya 15
PH - Filippine 15
PE - Perù 14
TN - Tunisia 13
CR - Costa Rica 12
EG - Egitto 12
AE - Emirati Arabi Uniti 11
SK - Slovacchia (Repubblica Slovacca) 11
JO - Giordania 10
KZ - Kazakistan 10
PT - Portogallo 10
TH - Thailandia 10
DZ - Algeria 9
NP - Nepal 9
AZ - Azerbaigian 8
TW - Taiwan 8
AU - Australia 7
EU - Europa 6
AL - Albania 5
BO - Bolivia 5
GR - Grecia 5
GT - Guatemala 5
HN - Honduras 5
HR - Croazia 5
IR - Iran 5
LV - Lettonia 5
MD - Moldavia 5
AO - Angola 4
KG - Kirghizistan 4
PS - Palestinian Territory 4
RS - Serbia 4
BG - Bulgaria 3
BH - Bahrain 3
CH - Svizzera 3
GA - Gabon 3
GH - Ghana 3
HU - Ungheria 3
NG - Nigeria 3
NI - Nicaragua 3
OM - Oman 3
PA - Panama 3
PR - Porto Rico 3
QA - Qatar 3
TT - Trinidad e Tobago 3
BA - Bosnia-Erzegovina 2
BS - Bahamas 2
BY - Bielorussia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
KH - Cambogia 2
LB - Libano 2
MN - Mongolia 2
RO - Romania 2
Totale 30.964
Città #
Helsinki 3.819
Dallas 1.750
Singapore 1.529
Ashburn 1.455
Fairfield 1.101
Woodbridge 1.037
San Jose 923
Ann Arbor 606
Beijing 565
Houston 564
Hong Kong 547
Santa Clara 537
Jacksonville 534
Chandler 500
Seattle 436
Wilmington 402
Cambridge 338
Ferrara 295
Council Bluffs 255
Ho Chi Minh City 250
Munich 204
New York 202
Hanoi 193
Los Angeles 190
Izmir 184
Nanjing 154
Princeton 131
Tokyo 131
Boardman 122
Lauterbourg 112
San Diego 111
Shanghai 110
Warsaw 103
Milan 102
São Paulo 93
Turku 76
Dong Ket 64
Orem 64
Mexico City 62
Bremen 57
Montreal 56
Bologna 54
London 54
Hefei 51
Chicago 50
Nanchang 50
Shenyang 50
Tianjin 49
Frankfurt am Main 48
Toronto 47
Atlanta 45
Brooklyn 45
Brussels 45
Jakarta 45
Falkenstein 40
Phoenix 40
Rio de Janeiro 39
Johannesburg 38
Chennai 37
Changsha 36
Dearborn 35
Da Nang 34
Denver 34
Rome 34
Buffalo 33
San Mateo 32
Hebei 30
Poplar 29
Boston 27
Falls Church 27
Jiaxing 27
Philadelphia 27
Redwood City 27
Amsterdam 26
Guangzhou 26
Haiphong 26
Moscow 26
Mountain View 25
Tashkent 24
Baghdad 23
Brasília 23
San Francisco 23
Stockholm 23
Washington 23
Ankara 22
Belo Horizonte 22
The Dalles 22
Manchester 21
Addison 20
Zhengzhou 20
Mumbai 19
Curitiba 18
Memphis 17
Hải Dương 16
Jinan 16
Kunming 16
Biên Hòa 15
Columbus 15
Dublin 15
Nuremberg 15
Totale 21.780
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.110
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 2.954
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 339
A3 adenosine receptor antagonists: History and future perspectives 294
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 283
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 268
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 268
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 258
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 256
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 249
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 249
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 249
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 248
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 247
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 246
Allosteric enhancers for A(1) adenosine receptor 244
DNA minor groove binders as potential antitumor and antimicrobial agents 244
History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents 244
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 242
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 239
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice 235
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 234
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents 230
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 229
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 228
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 226
Hybrid molecules between distamycin A and active moieties of antitumor agents 226
Hybrid molecules based on distamycin A as potential antitumor agents 225
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 224
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation 223
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain 222
Neuropeptide S receptor ligands: a patent review (2005-2016) 222
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 218
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 217
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 216
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 216
Adenosine modulates HIF-1, VEGF, IL-8 and foam cells formation in a human model of hypoxic foam cells 214
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 214
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 211
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 211
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 211
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 211
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 211
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 210
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 210
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain 209
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 209
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 205
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 204
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 204
Recent developments in the field of adenosine receptor ligands. 203
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents 203
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 202
Recent improvements in the development of A2B adenosine receptor agonists 202
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 201
Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies 201
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 199
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 198
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 197
Recent improvements in the development of A2B adenosine receptor agonists 195
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 195
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 194
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 194
Adenosine in a human model of Hypoxic foam cells 193
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 190
alpha-Halogenoacrylic Derivatives of Antitumor Agents 190
Adenosine modulates HIF-1α, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells 189
New strategies for the synthesis of A(3) adenosine receptor antagonists 189
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system 188
Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice 183
New 2-arylpyrazolo[4,3-c]quinoline derivates as potent and selective human A3 adenosine receptor antagonists 183
Ozone-induced hypertussive responses in rabbits and guinea pigs 181
Design, synthesis, and biological evaluation of C-9- and C-2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A(2A) and A(3) adenosine receptors antagonists 180
Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications 178
Synthesis and biological evaluation of novel N-6-[4-(substituted) sulfonamidophenylcarbamoyl]adenosine-5 '-uronamides as A(3) adenosine receptor agonists 176
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 176
Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents 175
Novel Mixed NOP/Opioid Receptor Peptide Agonists 175
Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors 174
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents 174
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 173
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents 173
Recent improvements in the field of A(3) adenosine receptor ligands 170
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 169
Preparation of fused purine derivatives as adenosine A3 receptor modulators. 168
Synthesis and biological evaluation of 2-substituted-4-(3 ',4 ',5 '-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents 166
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 166
COMPOSTI 1,3,8-TRIAZASPIRO E LORO USO COME MEDICAMENTI 164
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor 163
COMPOSTI PIRROLIDINICI E PIPERIDINICI COME INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO COME MEDICAMENTI 162
The P2X7 receptor as a therapeutic target 161
TRP channels as therapeutic targets in airway disorders: a patent review 160
Ligands for A(2B) adenosine receptor subtype 158
Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties 158
New pyrrolo [2,1-f] purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione derivates as potent and selective human A3 adenosine receptor antagonists 157
COMPOSTI SOLFONAMMIDICI COME INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO COME MEDICAMENTI 154
Compounds as nlrp3 inflammasome inhibitors and their use as medicaments 153
Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase 151
Spiropiperidine-Based Oligomycin-Analog Ligands To Counteract the Ischemia–Reperfusion Injury in a Renal Cell Model 143
Novel 1,3-Dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as Potent and Selective A2B Adenosine Receptor Antagonists 142
Totale 26.145
Categoria #
all - tutte 112.924
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.643
Totale 115.567


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.303 0 127 137 55 88 61 84 57 47 105 140 402
2022/20231.270 132 86 23 181 239 171 53 92 169 9 64 51
2023/2024831 59 96 49 25 60 137 41 90 25 19 22 208
2024/20253.344 85 99 271 144 350 322 103 194 474 348 494 460
2025/202615.001 975 962 2.043 1.139 1.350 682 1.077 514 4.551 1.135 402 171
2026/2027716 389 327 0 0 0 0 0 0 0 0 0 0
Totale 31.211