ROMAGNOLI, Romeo
 Distribuzione geografica
Continente #
NA - Nord America 27.865
AS - Asia 13.543
EU - Europa 11.652
SA - Sud America 2.167
Continente sconosciuto - Info sul continente non disponibili 352
AF - Africa 284
OC - Oceania 17
Totale 55.880
Nazione #
US - Stati Uniti d'America 27.294
SG - Singapore 4.912
FI - Finlandia 4.268
CN - Cina 3.632
DE - Germania 2.127
BR - Brasile 1.693
VN - Vietnam 1.372
UA - Ucraina 1.316
HK - Hong Kong 1.224
TR - Turchia 953
GB - Regno Unito 826
IT - Italia 810
RU - Federazione Russa 576
SE - Svezia 543
FR - Francia 513
IN - India 261
CA - Canada 248
JP - Giappone 244
BD - Bangladesh 237
MX - Messico 211
PL - Polonia 183
AR - Argentina 160
ID - Indonesia 121
ZA - Sudafrica 111
IQ - Iraq 104
ES - Italia 92
NL - Olanda 87
CO - Colombia 77
PK - Pakistan 73
BE - Belgio 71
EC - Ecuador 67
VE - Venezuela 63
SA - Arabia Saudita 45
UZ - Uzbekistan 44
LT - Lituania 42
PH - Filippine 40
MA - Marocco 39
AT - Austria 38
EG - Egitto 35
AE - Emirati Arabi Uniti 34
MY - Malesia 33
TN - Tunisia 32
CL - Cile 29
KR - Corea 27
CZ - Repubblica Ceca 26
PY - Paraguay 26
JM - Giamaica 24
IL - Israele 22
CR - Costa Rica 21
IE - Irlanda 18
KE - Kenya 17
TW - Taiwan 17
UY - Uruguay 17
AU - Australia 16
NP - Nepal 16
PE - Perù 16
TH - Thailandia 15
AZ - Azerbaigian 14
BO - Bolivia 14
JO - Giordania 12
OM - Oman 12
TT - Trinidad e Tobago 12
SK - Slovacchia (Repubblica Slovacca) 11
AL - Albania 10
ET - Etiopia 10
EU - Europa 10
HN - Honduras 10
IR - Iran 10
LB - Libano 10
RO - Romania 10
CH - Svizzera 9
DZ - Algeria 9
KG - Kirghizistan 9
PT - Portogallo 9
GR - Grecia 8
HR - Croazia 8
KZ - Kazakistan 8
LV - Lettonia 8
MN - Mongolia 8
PS - Palestinian Territory 8
BG - Bulgaria 7
DO - Repubblica Dominicana 7
GT - Guatemala 7
BY - Bielorussia 6
PA - Panama 6
SV - El Salvador 6
AO - Angola 5
BH - Bahrain 5
HU - Ungheria 5
NI - Nicaragua 5
GA - Gabon 4
MD - Moldavia 4
RS - Serbia 4
SN - Senegal 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BA - Bosnia-Erzegovina 3
BB - Barbados 3
CI - Costa d'Avorio 3
DK - Danimarca 3
GE - Georgia 3
Totale 55.480
Città #
Helsinki 3.919
Singapore 3.147
Ashburn 2.818
Fairfield 2.522
Woodbridge 2.398
San Jose 1.636
Houston 1.574
Jacksonville 1.394
Chandler 1.308
Ann Arbor 1.234
Hong Kong 1.187
Dallas 1.123
Santa Clara 1.122
Beijing 1.095
Seattle 915
Wilmington 846
Cambridge 763
Council Bluffs 651
Izmir 473
Nanjing 436
Ho Chi Minh City 432
Los Angeles 369
Hanoi 318
Princeton 315
New York 268
Boardman 258
Ferrara 245
Lauterbourg 240
Munich 233
Tokyo 230
San Diego 229
Shanghai 164
São Paulo 162
Warsaw 162
Shenyang 146
Milan 143
Mexico City 129
Hefei 127
Nanchang 122
Orem 112
London 111
Tianjin 102
Bremen 101
Brooklyn 91
Changsha 87
Falkenstein 87
Hebei 85
San Mateo 80
Chicago 79
Jiaxing 77
Turku 75
Toronto 73
Montreal 72
Frankfurt am Main 70
Brussels 67
Phoenix 66
The Dalles 65
Atlanta 64
Buffalo 64
Jakarta 64
Dong Ket 62
Rio de Janeiro 62
Moscow 61
Chennai 57
Da Nang 57
Philadelphia 57
Denver 54
Johannesburg 54
Haiphong 52
Jinan 51
Norwalk 48
Baghdad 46
Stockholm 46
Zhengzhou 46
Kunming 45
San Francisco 45
Amsterdam 44
Falls Church 44
Dearborn 43
Addison 42
Boston 42
Mountain View 42
Guangzhou 41
Manchester 39
Tashkent 38
Brasília 37
Redwood City 35
Paris 34
Orange 33
Mumbai 32
Belo Horizonte 31
Des Moines 31
Quito 31
Hải Dương 30
Medellín 30
Poplar 30
Washington 30
Ankara 29
Curitiba 28
Indiana 27
Totale 38.231
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.111
Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale Distamicina A 1.971
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 536
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 330
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 309
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 304
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 301
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 299
A3 adenosine receptor antagonists: History and future perspectives 296
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 296
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 289
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 283
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 273
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 272
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 270
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 268
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 268
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 267
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 266
Allosteric modulators for the A1-adenosine receptor 261
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 260
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 258
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders 257
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 257
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 257
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 250
Fragment-based discovery of novel small molecule targeting human BAG3 249
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity 249
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 249
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 248
Allosteric enhancers for A(1) adenosine receptor 245
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 245
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 245
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 245
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 244
DNA minor groove binders as potential antitumor and antimicrobial agents 244
2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization 244
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 244
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 243
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 239
Mastering β-Keto Esters 238
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 235
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 234
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 231
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 231
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 229
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 229
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 228
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 228
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 227
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 227
Hybrid molecules between distamycin A and active moieties of antitumor agents 226
Hybrid molecules based on distamycin A as potential antitumor agents 226
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 225
Current status of A1 adenosine receptor allosteric enhancers 225
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 225
A Facile Synthesis of Diaryl Pyrroles Led to the Discovery of Potent Colchicine Site Antimitotic Agents 225
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 222
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 220
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 219
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 218
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 218
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 218
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 217
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 217
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 216
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 216
A new synthetic approach to indazole synthesis 216
Novel combretastatin analogues endowed with antitumor activity 216
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 215
2-aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents 214
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 212
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 212
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 212
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 212
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 211
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 211
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 210
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 210
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 209
A new synthetic approach to pyrazolo[3,4-c]-1,2,5-oxadiazoles 208
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 206
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 205
Recent developments in the field of adenosine receptor ligands. 204
Recent improvements in the development of A2B adenosine receptor agonists 203
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 202
[3H]MRE3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 201
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 201
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 199
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors 199
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 198
7-sobstituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonist: importance of modifications at the side chain on the activity and solubility. 196
Recent improvements in the development of A2B adenosine receptor agonists 196
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 196
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 195
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 194
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 191
New strategies for the synthesis of A(3) adenosine receptor antagonists 190
alpha-Halogenoacrylic Derivatives of Antitumor Agents 190
New potent and selective human adenosine A3 receptor antagonists. 190
Totale 28.236
Categoria #
all - tutte 227.306
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.097
Totale 228.403


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.946 0 307 271 154 169 131 143 142 100 238 329 962
2022/20232.979 318 175 74 421 526 456 91 265 388 17 158 90
2023/20241.656 148 197 84 38 110 197 67 360 24 17 43 371
2024/20256.037 119 199 487 240 726 540 165 377 935 683 817 749
2025/202621.929 1.703 979 2.080 2.228 2.421 1.199 2.004 882 5.318 2.057 792 266
2026/20271.291 526 765 0 0 0 0 0 0 0 0 0 0
Totale 55.880