ROMAGNOLI, Romeo
 Distribuzione geografica
Continente #
NA - Nord America 26.101
AS - Asia 13.252
EU - Europa 11.461
SA - Sud America 2.144
AF - Africa 284
Continente sconosciuto - Info sul continente non disponibili 16
OC - Oceania 16
Totale 53.274
Nazione #
US - Stati Uniti d'America 25.629
SG - Singapore 4.816
FI - Finlandia 4.268
CN - Cina 3.570
DE - Germania 2.126
BR - Brasile 1.681
VN - Vietnam 1.371
UA - Ucraina 1.316
HK - Hong Kong 1.172
TR - Turchia 952
GB - Regno Unito 824
IT - Italia 703
RU - Federazione Russa 576
FR - Francia 506
SE - Svezia 493
IN - India 259
JP - Giappone 243
MX - Messico 207
CA - Canada 192
PL - Polonia 181
BD - Bangladesh 170
AR - Argentina 158
ID - Indonesia 119
ZA - Sudafrica 111
IQ - Iraq 104
ES - Italia 86
NL - Olanda 80
CO - Colombia 74
PK - Pakistan 73
BE - Belgio 71
EC - Ecuador 66
VE - Venezuela 62
SA - Arabia Saudita 45
UZ - Uzbekistan 44
LT - Lituania 41
MA - Marocco 39
PH - Filippine 39
AT - Austria 38
EG - Egitto 35
AE - Emirati Arabi Uniti 33
TN - Tunisia 32
MY - Malesia 30
KR - Corea 27
CL - Cile 26
PY - Paraguay 26
CZ - Repubblica Ceca 25
IL - Israele 22
IE - Irlanda 17
KE - Kenya 17
NP - Nepal 16
PE - Perù 16
TW - Taiwan 16
UY - Uruguay 16
AU - Australia 15
AZ - Azerbaigian 14
BO - Bolivia 14
TH - Thailandia 14
CR - Costa Rica 12
JO - Giordania 12
OM - Oman 12
SK - Slovacchia (Repubblica Slovacca) 11
TT - Trinidad e Tobago 11
AL - Albania 10
ET - Etiopia 10
EU - Europa 10
IR - Iran 10
LB - Libano 10
DZ - Algeria 9
JM - Giamaica 9
KG - Kirghizistan 9
PT - Portogallo 9
RO - Romania 9
GR - Grecia 8
HR - Croazia 8
KZ - Kazakistan 8
LV - Lettonia 8
MN - Mongolia 8
PS - Palestinian Territory 8
BG - Bulgaria 7
DO - Repubblica Dominicana 7
CH - Svizzera 6
AO - Angola 5
BH - Bahrain 5
BY - Bielorussia 5
GT - Guatemala 5
HN - Honduras 5
HU - Ungheria 5
NI - Nicaragua 5
PA - Panama 5
GA - Gabon 4
RS - Serbia 4
SN - Senegal 4
SV - El Salvador 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BA - Bosnia-Erzegovina 3
CI - Costa d'Avorio 3
DK - Danimarca 3
GE - Georgia 3
KH - Cambogia 3
MD - Moldavia 3
Totale 53.214
Città #
Helsinki 3.919
Singapore 3.084
Ashburn 2.713
Fairfield 2.521
Woodbridge 2.398
Houston 1.568
San Jose 1.485
Jacksonville 1.387
Chandler 1.308
Ann Arbor 1.234
Hong Kong 1.135
Dallas 1.105
Beijing 1.048
Santa Clara 1.030
Seattle 912
Wilmington 846
Cambridge 763
Izmir 473
Nanjing 436
Ho Chi Minh City 432
Los Angeles 345
Hanoi 318
Princeton 313
Boardman 255
Ferrara 240
Lauterbourg 240
Munich 233
New York 232
San Diego 229
Tokyo 229
Shanghai 164
São Paulo 162
Warsaw 162
Shenyang 146
Milan 135
Hefei 127
Council Bluffs 126
Mexico City 125
Nanchang 121
Orem 111
London 109
Tianjin 102
Bremen 101
Brooklyn 87
Changsha 87
Falkenstein 87
Hebei 85
San Mateo 80
Jiaxing 77
Turku 75
Chicago 74
Frankfurt am Main 70
Brussels 67
Montreal 67
Jakarta 64
The Dalles 64
Dong Ket 62
Rio de Janeiro 62
Moscow 61
Atlanta 59
Chennai 57
Da Nang 57
Johannesburg 54
Haiphong 52
Phoenix 52
Denver 51
Jinan 51
Philadelphia 51
Toronto 50
Norwalk 48
Baghdad 46
Stockholm 46
Zhengzhou 46
Kunming 45
Amsterdam 44
Falls Church 44
Dearborn 43
Addison 42
Mountain View 42
Guangzhou 41
Boston 40
Buffalo 39
Manchester 38
Tashkent 38
Brasília 37
San Francisco 37
Redwood City 35
Orange 33
Paris 33
Mumbai 32
Belo Horizonte 31
Des Moines 31
Quito 31
Hải Dương 30
Medellín 30
Poplar 30
Ankara 29
Washington 29
Curitiba 28
Indiana 27
Totale 36.970
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.088
Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale Distamicina A 1.962
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 523
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 310
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 300
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 290
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 290
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 289
A3 adenosine receptor antagonists: History and future perspectives 284
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 277
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 274
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 272
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 263
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 263
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 263
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 262
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 261
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 259
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 257
Allosteric modulators for the A1-adenosine receptor 253
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 249
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders 248
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 247
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity 246
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 244
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 242
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 238
DNA minor groove binders as potential antitumor and antimicrobial agents 238
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 238
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 237
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 236
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 235
Allosteric enhancers for A(1) adenosine receptor 235
2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization 235
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 233
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 233
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 232
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 232
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 229
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 228
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 225
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 223
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 223
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 223
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 223
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 222
Hybrid molecules between distamycin A and active moieties of antitumor agents 221
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 220
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 219
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 219
Hybrid molecules based on distamycin A as potential antitumor agents 218
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 215
Current status of A1 adenosine receptor allosteric enhancers 215
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 214
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 214
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 212
Mastering β-Keto Esters 212
A Facile Synthesis of Diaryl Pyrroles Led to the Discovery of Potent Colchicine Site Antimitotic Agents 212
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 211
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 210
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 210
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 209
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 209
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 208
2-aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents 208
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 207
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 207
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 207
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 207
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 206
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 206
A new synthetic approach to indazole synthesis 206
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 206
A new synthetic approach to pyrazolo[3,4-c]-1,2,5-oxadiazoles 204
Novel combretastatin analogues endowed with antitumor activity 204
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 203
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 203
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 201
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 201
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 201
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 197
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 197
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 196
Recent developments in the field of adenosine receptor ligands. 195
Recent improvements in the development of A2B adenosine receptor agonists 195
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 194
7-sobstituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonist: importance of modifications at the side chain on the activity and solubility. 191
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 188
[3H]MRE3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 188
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 187
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 187
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors 187
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 186
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 186
New strategies for the synthesis of A(3) adenosine receptor antagonists 185
alpha-Halogenoacrylic Derivatives of Antitumor Agents 184
New potent and selective human adenosine A3 receptor antagonists. 184
Allosteric Modulators of the A1 Adenosine receptor 183
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 182
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 182
Totale 27.233
Categoria #
all - tutte 206.868
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.014
Totale 207.882


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021773 0 0 0 0 0 0 0 0 0 0 459 314
2021/20223.062 116 307 271 154 169 131 143 142 100 238 329 962
2022/20232.979 318 175 74 421 526 456 91 265 388 17 158 90
2023/20241.656 148 197 84 38 110 197 67 360 24 17 43 371
2024/20256.037 119 199 487 240 726 540 165 377 935 683 817 749
2025/202620.948 1.703 979 2.080 2.228 2.421 1.199 2.004 882 5.318 2.057 77 0
Totale 53.608