ROMAGNOLI, Romeo
 Distribuzione geografica
Continente #
NA - Nord America 26.812
AS - Asia 13.394
EU - Europa 11.540
SA - Sud America 2.144
AF - Africa 284
Continente sconosciuto - Info sul continente non disponibili 16
OC - Oceania 16
Totale 54.206
Nazione #
US - Stati Uniti d'America 26.314
SG - Singapore 4.857
FI - Finlandia 4.268
CN - Cina 3.583
DE - Germania 2.126
BR - Brasile 1.681
VN - Vietnam 1.371
UA - Ucraina 1.316
HK - Hong Kong 1.191
TR - Turchia 953
GB - Regno Unito 826
IT - Italia 770
RU - Federazione Russa 576
FR - Francia 506
SE - Svezia 493
IN - India 261
JP - Giappone 243
BD - Bangladesh 235
CA - Canada 211
MX - Messico 207
PL - Polonia 183
AR - Argentina 158
ID - Indonesia 119
ZA - Sudafrica 111
IQ - Iraq 104
ES - Italia 86
NL - Olanda 83
CO - Colombia 74
PK - Pakistan 73
BE - Belgio 71
EC - Ecuador 66
VE - Venezuela 62
SA - Arabia Saudita 45
UZ - Uzbekistan 44
LT - Lituania 42
MA - Marocco 39
PH - Filippine 39
AT - Austria 38
EG - Egitto 35
AE - Emirati Arabi Uniti 33
TN - Tunisia 32
MY - Malesia 30
KR - Corea 27
CL - Cile 26
PY - Paraguay 26
CZ - Repubblica Ceca 25
IL - Israele 22
IE - Irlanda 17
KE - Kenya 17
TW - Taiwan 17
NP - Nepal 16
PE - Perù 16
UY - Uruguay 16
AU - Australia 15
AZ - Azerbaigian 14
BO - Bolivia 14
TH - Thailandia 14
CR - Costa Rica 13
JO - Giordania 12
OM - Oman 12
TT - Trinidad e Tobago 12
JM - Giamaica 11
SK - Slovacchia (Repubblica Slovacca) 11
AL - Albania 10
ET - Etiopia 10
EU - Europa 10
IR - Iran 10
LB - Libano 10
CH - Svizzera 9
DZ - Algeria 9
KG - Kirghizistan 9
PT - Portogallo 9
RO - Romania 9
GR - Grecia 8
HR - Croazia 8
KZ - Kazakistan 8
LV - Lettonia 8
MN - Mongolia 8
PS - Palestinian Territory 8
BG - Bulgaria 7
DO - Repubblica Dominicana 7
HN - Honduras 7
AO - Angola 5
BH - Bahrain 5
BY - Bielorussia 5
GT - Guatemala 5
HU - Ungheria 5
NI - Nicaragua 5
PA - Panama 5
SV - El Salvador 5
GA - Gabon 4
MD - Moldavia 4
RS - Serbia 4
SN - Senegal 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BA - Bosnia-Erzegovina 3
CI - Costa d'Avorio 3
DK - Danimarca 3
GE - Georgia 3
KH - Cambogia 3
Totale 54.146
Città #
Helsinki 3.919
Singapore 3.113
Ashburn 2.754
Fairfield 2.522
Woodbridge 2.398
San Jose 1.591
Houston 1.573
Jacksonville 1.389
Chandler 1.308
Ann Arbor 1.234
Hong Kong 1.154
Dallas 1.118
Santa Clara 1.059
Beijing 1.056
Seattle 914
Wilmington 846
Cambridge 763
Izmir 473
Nanjing 436
Ho Chi Minh City 432
Los Angeles 359
Hanoi 318
Princeton 315
New York 265
Boardman 256
Ferrara 244
Lauterbourg 240
Munich 233
San Diego 229
Tokyo 229
Shanghai 164
São Paulo 162
Warsaw 162
Shenyang 146
Milan 138
Council Bluffs 129
Hefei 127
Mexico City 125
Nanchang 121
Orem 111
London 110
Tianjin 102
Bremen 101
Brooklyn 89
Changsha 87
Falkenstein 87
Hebei 85
San Mateo 80
Chicago 78
Jiaxing 77
Turku 75
Frankfurt am Main 70
Montreal 70
Brussels 67
Jakarta 64
The Dalles 64
Buffalo 63
Atlanta 62
Dong Ket 62
Rio de Janeiro 62
Moscow 61
Phoenix 58
Chennai 57
Da Nang 57
Philadelphia 55
Toronto 55
Denver 54
Johannesburg 54
Haiphong 52
Jinan 51
Norwalk 48
Baghdad 46
Stockholm 46
Zhengzhou 46
Kunming 45
Amsterdam 44
Falls Church 44
Dearborn 43
Addison 42
Mountain View 42
San Francisco 42
Boston 41
Guangzhou 41
Manchester 38
Tashkent 38
Brasília 37
Redwood City 35
Orange 33
Paris 33
Mumbai 32
Belo Horizonte 31
Des Moines 31
Quito 31
Hải Dương 30
Medellín 30
Poplar 30
Ankara 29
Washington 29
Curitiba 28
Indiana 27
Totale 37.346
Nome #
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists 3.095
Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale Distamicina A 1.964
[2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid inhibits DNA binding to transcription factor Sp1 528
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy 315
A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion 302
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety 302
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents 295
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition 294
1-methyl-3-nitro-5-methoxycarbonyl pyrazole 292
A3 adenosine receptor antagonists: History and future perspectives 286
Effects of Pimozide Derivatives on pSTAT5 in K562 Cells 281
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor 277
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole 268
A synthetic approach for the preparation of rigid analogs of 1,3-dipropyl-7-methyl-8-aryl/heteroarylstyryl xanthines 264
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives. 264
A one-pot synthesis of nitrohydroxylated pyrrolidine and piperidine ring systems by tandem Michael-Henry reaction 263
Synthesis and biological evaluation of 2-and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization 263
A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol 263
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation 262
Allosteric modulators for the A1-adenosine receptor 256
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin 256
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists 253
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders 252
[H-3]-MRE 2029-F20, a selective antagonist radioligand for the human A(2B) adenosine receptors 250
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity 246
New 2-heterocyclyl-imidazo[2,1- i ]purin-5-one derivatives as potent and selective human A 3 adenosine receptor antagonists 246
[H-3]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors 245
Fragment-based discovery of novel small molecule targeting human BAG3 242
N-6-[(Hetero)aryl/(cyclo)alkyl-carbamoyi-methoxy-phenyl]-(2chloro)-5 '-N-ethylearboxamido-adenosines: The first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor 242
DNA minor groove binders as potential antitumor and antimicrobial agents 241
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2. 241
Pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine template: Organic and medicinal chemistry approach 240
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines 240
Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds 240
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents 240
Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology 238
Allosteric enhancers for A(1) adenosine receptor 238
2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization 238
Design, synthesis and in vitro cytotoxicity of a cis-dichloroplatinum(II) complex linked to the minor groove binder stallimycin 236
Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA 231
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation 230
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor 229
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) 228
From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X(7) receptor 226
Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles 225
One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists 225
1H-pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a new class of human leukocyte elastase inhibitors 224
Novel 8-heterocyclyl xanthine derivatives in drug development - An update 224
Hybrid molecules between distamycin A and active moieties of antitumor agents 223
Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: Induction of production of fetal hemoglobin in human erythroid precursor cells 222
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity 221
Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers 220
A Facile Synthesis of Diaryl Pyrroles Led to the Discovery of Potent Colchicine Site Antimitotic Agents 220
Current status of A1 adenosine receptor allosteric enhancers 219
Hybrid molecules based on distamycin A as potential antitumor agents 219
Mastering β-Keto Esters 217
Biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptors 217
Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors 216
New heterocyclic ligands for the adenosine receptors P1 and for the ATP receptors P2 216
Synthesis of a new series of pyrazolo[1,5-a]pyrimidines structurally related to zaleplon 213
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents 213
Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors 212
Novel combretastatin analogues endowed with antitumor activity 212
Structure-activity relationship studies of a new series of imidazo[2,1-f] purinones as potent and selective A3 adenosine receptor antagonists 211
A mild one-pot synthesis of thieno[3,4-c]pyrazoles and their conversion into pyrazole analogs of o-quinodimethane 210
Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor 210
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists 209
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 209
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and linked Heterocycles as template for the adenosine receptor antagonism: Medicinal chemistry approach and sar considerations 209
7-substituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: importance of modifications at the side chain on the activity and solubility. 209
Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents 209
A new synthetic approach to indazole synthesis 209
7-substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A(2A) adenosine receptor antagonists: A study on the importance of modifications at the side chain on the activity and solubility 209
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies 208
2-aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents 208
Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety 206
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 205
A new synthetic approach to pyrazolo[3,4-c]-1,2,5-oxadiazoles 205
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach 204
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxyphenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents 203
Synthesis and Biological Evaluation of Novel Allosteric Enhancers of the A1 Adenosine Receptor Based on 2-Amino-3-(4’-Chlorobenzoyl)-4-Substituted-5-Arylethynyl Thiophene 203
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists 202
[3H]-MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 202
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A(3) adenosine receptor antagonists 199
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N- (substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor 198
Recent developments in the field of adenosine receptor ligands. 197
Recent improvements in the development of A2B adenosine receptor agonists 196
Synthesis and Biological Evaluation of 1-Methyl-2-(3’,4’,5’-Trimethoxybenzoyl)-3-Amino Indoles as a New Class of Antimitotic Agents and Tubulin Inhibitors 195
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors 193
Recent developments in the field of A(2A) and A(3) adenosine receptor antagonists 192
7-sobstituted-5-amino-2-(furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonist: importance of modifications at the side chain on the activity and solubility. 192
[3H]MRE3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 191
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists 190
Microwave-assisted synthesis of substituted 2,4-diarylthiazoles and their evaluation as anticancer agents 189
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor 188
Recent improvements in the development of A2B adenosine receptor agonists 187
New strategies for the synthesis of A(3) adenosine receptor antagonists 186
Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells 185
alpha-Halogenoacrylic Derivatives of Antitumor Agents 185
New potent and selective human adenosine A3 receptor antagonists. 185
Totale 27.648
Categoria #
all - tutte 217.144
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.054
Totale 218.198


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021314 0 0 0 0 0 0 0 0 0 0 0 314
2021/20223.062 116 307 271 154 169 131 143 142 100 238 329 962
2022/20232.979 318 175 74 421 526 456 91 265 388 17 158 90
2023/20241.656 148 197 84 38 110 197 67 360 24 17 43 371
2024/20256.037 119 199 487 240 726 540 165 377 935 683 817 749
2025/202621.880 1.703 979 2.080 2.228 2.421 1.199 2.004 882 5.318 2.057 792 217
Totale 54.540