SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

PINOTTI, Mirko
 Distribuzione geografica
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Continente #
NA - Nord America 21.232
EU - Europa 11.575
AS - Asia 11.405
SA - Sud America 1.646
Continente sconosciuto - Info sul continente non disponibili 517
AF - Africa 261
OC - Oceania 24
AN - Antartide 1
Totale 46.661
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Nazione #
US - Stati Uniti d'America 20.683
FI - Finlandia 6.027
SG - Singapore 4.224
CN - Cina 2.873
IT - Italia 1.375
VN - Vietnam 1.285
BR - Brasile 1.260
DE - Germania 1.093
HK - Hong Kong 843
UA - Ucraina 784
GB - Regno Unito 578
TR - Turchia 545
FR - Francia 370
BD - Bangladesh 336
JP - Giappone 307
PL - Polonia 302
CA - Canada 293
IN - India 257
RU - Federazione Russa 257
SE - Svezia 245
ID - Indonesia 201
MX - Messico 175
AR - Argentina 144
ZA - Sudafrica 101
NL - Olanda 95
IQ - Iraq 88
ES - Italia 83
BE - Belgio 82
EC - Ecuador 64
PK - Pakistan 59
UZ - Uzbekistan 51
CO - Colombia 50
VE - Venezuela 46
MY - Malesia 41
AT - Austria 38
CZ - Repubblica Ceca 37
KE - Kenya 33
SA - Arabia Saudita 30
MA - Marocco 29
LT - Lituania 28
CL - Cile 26
NO - Norvegia 25
PH - Filippine 25
CH - Svizzera 24
JO - Giordania 22
AE - Emirati Arabi Uniti 21
JM - Giamaica 21
KR - Corea 21
AU - Australia 20
IR - Iran 20
PT - Portogallo 20
DZ - Algeria 19
IL - Israele 18
PY - Paraguay 17
PE - Perù 16
CR - Costa Rica 15
IE - Irlanda 15
AL - Albania 14
DK - Danimarca 14
ET - Etiopia 14
GE - Georgia 14
RO - Romania 14
TH - Thailandia 14
TN - Tunisia 14
AZ - Azerbaigian 13
KZ - Kazakistan 13
NP - Nepal 13
BO - Bolivia 10
TW - Taiwan 10
KG - Kirghizistan 9
NG - Nigeria 9
UY - Uruguay 9
GR - Grecia 7
RS - Serbia 7
SN - Senegal 7
BG - Bulgaria 6
DO - Repubblica Dominicana 6
EG - Egitto 6
GT - Guatemala 6
HN - Honduras 6
LB - Libano 6
PS - Palestinian Territory 6
TT - Trinidad e Tobago 6
BH - Bahrain 5
BY - Bielorussia 5
OM - Oman 5
SV - El Salvador 5
BA - Bosnia-Erzegovina 4
BW - Botswana 4
GA - Gabon 4
KH - Cambogia 4
KW - Kuwait 4
LA - Repubblica Popolare Democratica del Laos 4
LU - Lussemburgo 4
LV - Lettonia 4
MT - Malta 4
PA - Panama 4
AF - Afghanistan, Repubblica islamica di 3
CG - Congo 3
EU - Europa 3
Totale 46.079
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Città #
Helsinki 5.818
Singapore 2.612
Ashburn 2.208
Fairfield 1.429
Woodbridge 1.423
San Jose 1.418
Dallas 1.324
Santa Clara 999
Chandler 991
Houston 968
Beijing 934
Hong Kong 816
Jacksonville 815
Ann Arbor 719
Seattle 618
Wilmington 559
Cambridge 475
Council Bluffs 457
Ho Chi Minh City 415
Ferrara 411
New York 403
Los Angeles 353
Hanoi 321
Munich 317
Izmir 309
Warsaw 288
Tokyo 286
Nanjing 256
Princeton 233
Lauterbourg 196
Milan 182
Shanghai 165
Boardman 164
Jakarta 150
São Paulo 139
San Diego 137
Orem 123
Dearborn 109
Mexico City 106
Bremen 105
Toronto 105
Montreal 88
London 87
Nanchang 84
The Dalles 78
Brooklyn 75
Brussels 74
Shenyang 73
Denver 72
Chicago 71
Atlanta 70
Tianjin 70
Buffalo 69
Phoenix 63
Chennai 60
Falls Church 60
Da Nang 57
Frankfurt am Main 57
Jiaxing 57
Johannesburg 56
Redwood City 54
Changsha 52
Hefei 51
Rome 51
Moscow 48
Poplar 48
Hebei 45
Rio de Janeiro 45
San Francisco 44
Tashkent 44
Bologna 43
Haiphong 43
Jinan 43
Stockholm 42
Guangzhou 41
Turku 39
Manchester 38
Baghdad 37
San Mateo 37
Amsterdam 36
Falkenstein 36
Mountain View 35
Belo Horizonte 33
Curitiba 33
Dong Ket 33
Norwalk 32
Nuremberg 32
Kunming 30
Des Moines 28
Mumbai 28
Paris 28
Washington 28
Ankara 26
Biên Hòa 26
Columbus 26
Nairobi 25
Naples 25
Philadelphia 25
Auburn Hills 24
Boston 24
Totale 32.635
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Nome #
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.871
A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients 2.061
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2.054
Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency 312
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth 311
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 308
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 300
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 300
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 291
Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings 286
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 283
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 276
Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties 275
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates 267
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 263
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY 260
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 255
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 254
Factor XIII-A dynamics in acute myocardial infarction: a novel prognostic biomarker? 249
Responsiveness of hemophilia B- causing non sense mutations to ribosome readthrough-inducing drugs strictly depends on the nucleotide and prrotein context 248
Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics 247
Attività sulla emostasi di alcune piante della medicina tradizionale indiana 246
Chronic sleep deprivation markedly reduces coagulation factor VII expression 246
Membrane binding and anticoagulant properties of protein S natural variants 244
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 243
The carboxyl-terminal region is not essential for secreted and functional levels of coagulation factor X 242
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 241
Cationic lipid nanosystems as carriers for nucleic acids 238
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity 236
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 236
Nuove strategie per la veicolazione di acidi nucleici: nanosistemi cationici a matrice lipidica 234
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 234
Evidence for an overlapping role of clock and npas2 transcription factors in liver circadian oscillators 232
Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model 226
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis 225
Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster 225
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics 224
Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile 223
Mutation pattern in clinically asymptomatic coagulation factor VII deficiency 223
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 223
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 222
Effective hemostasis during minor surgery in a case of hereditary combined deficiency of vitamin K-dependent clotting factors 220
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 220
Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation 217
The dominant-negative von Willebrand factor gene deletion p.P1127-C1948delinsR: Molecular mechanism and modulation 216
The factor V Glu1608Lys mutation is recurrent in familial thrombophilia 215
FXIII levels and genotypes in myocardial infarction: a potential novel prognostic biomarker? 215
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 215
Temporal variations of coagulation factor VII activity in mice are influenced by lighting regime 214
Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function 214
Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition 213
The carboxyl-terminal region is NOT essential for secreted and functional levels of coagulation factor X 211
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene 209
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 207
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 206
Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glul02Lys) in the second EGF‐like domain 205
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. 204
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations 204
Ribosome readthrough accounts for secreted full-length factor IX in hemophilia B patients with nonsense mutations 203
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 203
Cationic lipid nanosystems as carriers for nucleic acids 200
Factor VII mutant V154G models a zymogen-like form of factor VIIa 199
Residual factor VII activity and different hemorrhagic phenotypes in CRM+ factor VII deficiencies (Gly331Ser and Gly283Ser) 198
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency 198
Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency 197
CRISPR activation on coagulation F7 or F8 promoters potentiate trascriptional activity in the normal and mutated gene context 197
Nanosistemi lipidici per la veicolazione di acidi nucleici 196
Circadian rhythms in mouse blood coagulation 195
Characterization of PAR-mediated signaling induced by activated coagulation factor X mutants 193
Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity 189
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 188
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency 188
Molecular mechanisms of FVII deficiency: Expression of mutations clustered in the IVS7 donor splice site of factor VII gene 187
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies 187
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA 187
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 186
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 185
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 184
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. 183
Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis 183
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity 182
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 182
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 181
Cationic nanostructured lipid carrier (NLC) and monoolein aqueous dispersions (MAD) as potential carriers for nucleic acids 180
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 180
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 180
Association of the homozygous nonsense mutation R402X in coagulation factor VII with asymptomatic phenotype 180
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors 179
Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII 178
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 176
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 175
Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma 174
A next-generation rFVIIa fusion protein with enhanced half-life as a novel by-passing tool in hemophilia 174
Rescue of coagulation factor VII function by the U1+5A snRNA 172
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 172
FXIII Levels in Myocardial Infarction: a Potential Novel Prognostic Biomarker? 171
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity 170
An engineered factor X variant as a novel by-passing agent for hemophilia 169
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease 169
Impaired prothrombinase activity of factor X Gly381 Asp results in severe familial CRM+ FX deficiency 169
Totale 27.978
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Categoria #
all - tutte 190.226
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.312
Totale 191.538
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.111 0 262 114 73 113 104 112 106 80 187 185 775
2022/20232.359 261 184 73 301 409 315 135 179 276 15 128 83
2023/20241.269 110 140 79 45 79 210 50 77 36 48 40 355
2024/20255.698 175 117 507 179 696 710 172 233 886 585 781 657
2025/202622.734 1.530 905 1.944 2.153 2.378 1.073 1.986 921 6.992 1.668 760 424
2026/20271.097 591 506 0 0 0 0 0 0 0 0 0 0
Totale 46.661