SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

PINOTTI, Mirko
 Distribuzione geografica
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Continente #
NA - Nord America 12.885
EU - Europa 3.811
AS - Asia 3.758
SA - Sud America 190
AF - Africa 22
OC - Oceania 13
Continente sconosciuto - Info sul continente non disponibili 5
Totale 20.684
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Nazione #
US - Stati Uniti d'America 12.823
SG - Singapore 1.546
CN - Cina 1.326
IT - Italia 959
DE - Germania 778
UA - Ucraina 742
TR - Turchia 477
GB - Regno Unito 326
FI - Finlandia 301
PL - Polonia 204
BR - Brasile 170
SE - Svezia 165
ID - Indonesia 138
BE - Belgio 79
HK - Hong Kong 55
CA - Canada 54
IN - India 50
NL - Olanda 47
FR - Francia 46
RU - Federazione Russa 35
VN - Vietnam 34
CZ - Repubblica Ceca 32
JP - Giappone 19
IR - Iran 18
IQ - Iraq 14
KR - Corea 12
AT - Austria 11
AU - Australia 11
CH - Svizzera 11
NO - Norvegia 11
RO - Romania 11
ZA - Sudafrica 11
DK - Danimarca 10
GE - Georgia 9
PT - Portogallo 9
TW - Taiwan 9
UZ - Uzbekistan 7
BD - Bangladesh 6
IE - Irlanda 6
LT - Lituania 6
PK - Pakistan 6
IL - Israele 5
CO - Colombia 4
ES - Italia 4
LU - Lussemburgo 4
MX - Messico 4
AE - Emirati Arabi Uniti 3
AR - Argentina 3
AZ - Azerbaigian 3
BG - Bulgaria 3
EC - Ecuador 3
EU - Europa 3
JO - Giordania 3
KE - Kenya 3
KZ - Kazakistan 3
LA - Repubblica Popolare Democratica del Laos 3
MA - Marocco 3
TH - Thailandia 3
BY - Bielorussia 2
CL - Cile 2
GR - Grecia 2
KG - Kirghizistan 2
MY - Malesia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PA - Panama 2
PE - Perù 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BO - Bolivia 1
CR - Costa Rica 1
DZ - Algeria 1
EE - Estonia 1
GT - Guatemala 1
HR - Croazia 1
HU - Ungheria 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
MT - Malta 1
PH - Filippine 1
PS - Palestinian Territory 1
PY - Paraguay 1
QA - Qatar 1
SA - Arabia Saudita 1
SN - Senegal 1
SR - Suriname 1
TN - Tunisia 1
VE - Venezuela 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 20.684
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Città #
Fairfield 1.429
Woodbridge 1.423
Chandler 991
Houston 915
Santa Clara 854
Jacksonville 812
Singapore 730
Ann Arbor 719
Ashburn 694
Seattle 598
Wilmington 555
Cambridge 474
Ferrara 369
Izmir 307
Nanjing 255
Princeton 232
Beijing 215
Warsaw 203
New York 160
Boardman 149
Shanghai 145
Helsinki 137
San Diego 132
Jakarta 131
Milan 128
Munich 110
Dearborn 109
Bremen 105
Los Angeles 88
Nanchang 84
Brussels 71
Shenyang 71
Falls Church 60
Jiaxing 57
Redwood City 54
Tianjin 48
Hebei 45
Changsha 44
Jinan 42
Toronto 42
Hong Kong 40
London 40
San Mateo 37
Mountain View 35
Dong Ket 33
Bologna 31
Kunming 30
Norwalk 30
Falkenstein 29
Des Moines 28
Guangzhou 28
The Dalles 25
Auburn Hills 24
Ningbo 24
Brno 23
Padova 20
Zhengzhou 20
São Paulo 18
Washington 18
Orange 17
Frankfurt am Main 16
Monmouth Junction 16
Nuremberg 16
Düsseldorf 14
Indiana 14
Naples 13
Rome 13
Augusta 12
Hangzhou 12
Leawood 12
Florence 11
Council Bluffs 10
Hefei 10
Ottawa 10
Philadelphia 10
Taizhou 10
Baghdad 9
Ferrara di Monte Baldo 9
Paris 9
Piemonte 9
Verona 9
Copenhagen 8
Fairford 8
Mānsa 8
Oslo 8
Andover 7
Chicago 7
Fuzhou 7
Hounslow 7
Olomouc 7
Redmond 7
Tokyo 7
Addison 6
Dublin 6
Rochester 6
Taipei 6
Clifton 5
Curitiba 5
Espoo 5
Jyväskylä 5
Totale 14.706
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Nome #
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 199
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 198
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 194
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 192
Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency 185
Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings 177
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 169
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth 167
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 161
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 159
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 158
Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile 153
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY 152
The carboxyl-terminal region is NOT essential for secreted and functional levels of coagulation factor X 152
Nuove strategie per la veicolazione di acidi nucleici: nanosistemi cationici a matrice lipidica 148
Chronic sleep deprivation markedly reduces coagulation factor VII expression 147
Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics 147
Responsiveness of hemophilia B- causing non sense mutations to ribosome readthrough-inducing drugs strictly depends on the nucleotide and prrotein context 143
Factor XIII-A dynamics in acute myocardial infarction: a novel prognostic biomarker? 143
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations 142
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 139
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates. 139
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 139
Cationic lipid nanosystems as carriers for nucleic acids 138
The dominant-negative von Willebrand factor gene deletion p.P1127-C1948delinsR: Molecular mechanism and modulation 137
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 134
The carboxyl-terminal region is not essential for secreted and functional levels of coagulation factor X 133
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 132
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 131
Cationic lipid nanosystems as carriers for nucleic acids 131
Effective hemostasis during minor surgery in a case of hereditary combined deficiency of vitamin K-dependent clotting factors 129
Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation 129
Circadian rhythms in mouse blood coagulation 128
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency 127
Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster 126
Temporal variations of coagulation factor VII activity in mice are influenced by lighting regime 125
Attività sulla emostasi di alcune piante della medicina tradizionale indiana 125
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis 125
Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII 124
Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency 123
Ribosome readthrough accounts for secreted full-length factor IX in hemophilia B patients with nonsense mutations 123
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 123
Major differences in bleeding symptoms between factor VII deficiency and hemophilia B 122
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 122
Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function 121
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity 121
Membrane binding and anticoagulant properties of protein S natural variants 121
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease. 120
Mutation pattern in clinically asymptomatic coagulation factor VII deficiency 120
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 119
Residual factor VII activity and different hemorrhagic phenotypes in CRM+ factor VII deficiencies (Gly331Ser and Gly283Ser) 118
Nanosistemi lipidici per la veicolazione di acidi nucleici 118
Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glul02Lys) in the second EGF‐like domain 117
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. 116
Detection and characterization of polymorphic markers in the factor-VII gene. 116
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 116
Evidence for an overlapping role of clock and npas2 transcription factors in liver circadian oscillators 115
Rescue of coagulation factor VII function by the U1+5A snRNA 115
Gentamicin induces sub-therapeutic levels of coagulation factor VII in patients with nonsense mutations 115
Factor VII mutant V154G models a zymogen-like form of factor VIIa 113
FXIII levels and genotypes in myocardial infarction: a potential novel prognostic biomarker? 113
Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis 113
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 113
RNA-based therapeutic approaches for coagulation factor deficiencies 111
Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity 111
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 111
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies 110
Intracellular evaluation of ER targeting elucidates a mild form of inherited coagulation deficiency 110
Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model 110
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 110
The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies 110
Polymorphic changes in the 5' flanking region of factor VII have a combined effect on promoter strength 109
The factor V Glu1608Lys mutation is recurrent in familial thrombophilia 109
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 109
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. 109
Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition 109
Impaired prothrombinase activity of factor X Gly381 Asp results in severe familial CRM+ FX deficiency 108
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 108
Molecular mechanisms of FVII deficiency: expression of mutations clustered in the IVS7 donor splice site of factor VII gene. 107
Promoter methylation in coagulation F7 gene influences plasma FVII concentrations and relates to coronary artery disease. 106
Management of Kidney Transplantation in a Factor VII-Deficient Patient: Case Report 106
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity 105
Modulation of factor V levels in plasma by polymorphisms in the C2 domain 105
Detection of two missense mutations and characterization of a repeat polymorphism in the factor VII gene (F7) 104
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors 104
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 103
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency 102
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 101
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA 101
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 100
Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy 100
Pharmacokinetic properties of recombinant FVIIa in inherited FVII deficiency account for a large volume of distribution at steady state and a prolonged pharmacodynamic effect 99
Reduced activation of the Gla19Ala FX variant via the extrinsic coagulation pathway results in symptomatic CRMred FX deficiency 98
Contribution of factor VII genotype to activated FVII levels. Differences in genotype frequencies between northern and southern European populations. 97
Gene therapy-based prophylaxis to rescue the "prima ballerina" 97
Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma 96
Protein S mRNA in patients with protein S deficiency. 96
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene 96
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 96
Release of Tissue Factor-bearing microparticles by human dendritic cells induced by stimulation of membrane P2X7 receptors 94
Totale 12.467
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Categoria #
all - tutte 114.573
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 756
Totale 115.329
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020563 0 0 0 0 0 0 0 0 0 331 160 72
2020/20212.796 202 160 147 290 96 242 231 330 131 454 366 147
2021/20222.248 137 262 114 73 113 104 112 106 80 187 185 775
2022/20232.359 261 184 73 301 409 315 135 179 276 15 128 83
2023/20241.269 110 140 79 45 79 210 50 77 36 48 40 355
2024/20254.041 175 117 507 179 696 710 172 233 886 366 0 0
Totale 21.173