SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

PINOTTI, Mirko
 Distribuzione geografica
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Continente #
NA - Nord America 19.677
EU - Europa 11.261
AS - Asia 11.036
SA - Sud America 1.619
AF - Africa 257
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 7
AN - Antartide 1
Totale 43.878
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Nazione #
US - Stati Uniti d'America 19.256
FI - Finlandia 6.027
SG - Singapore 4.158
CN - Cina 2.808
VN - Vietnam 1.281
BR - Brasile 1.246
IT - Italia 1.144
DE - Germania 1.089
HK - Hong Kong 826
UA - Ucraina 782
GB - Regno Unito 570
TR - Turchia 545
FR - Francia 365
JP - Giappone 306
PL - Polonia 300
RU - Federazione Russa 257
IN - India 251
SE - Svezia 209
CA - Canada 203
ID - Indonesia 201
MX - Messico 173
AR - Argentina 142
BD - Bangladesh 130
ZA - Sudafrica 101
NL - Olanda 90
IQ - Iraq 88
BE - Belgio 81
ES - Italia 76
EC - Ecuador 61
PK - Pakistan 59
UZ - Uzbekistan 51
CO - Colombia 48
VE - Venezuela 42
MY - Malesia 40
AT - Austria 37
CZ - Repubblica Ceca 37
KE - Kenya 31
SA - Arabia Saudita 30
MA - Marocco 29
LT - Lituania 27
CL - Cile 25
NO - Norvegia 25
PH - Filippine 25
JO - Giordania 22
IR - Iran 20
KR - Corea 20
AE - Emirati Arabi Uniti 19
CH - Svizzera 19
PT - Portogallo 19
DZ - Algeria 18
IL - Israele 18
PY - Paraguay 17
AU - Australia 16
PE - Perù 16
AL - Albania 14
DK - Danimarca 14
ET - Etiopia 14
GE - Georgia 14
IE - Irlanda 14
RO - Romania 14
TH - Thailandia 14
AZ - Azerbaigian 13
KZ - Kazakistan 13
NP - Nepal 13
TN - Tunisia 13
CR - Costa Rica 12
BO - Bolivia 10
TW - Taiwan 10
JM - Giamaica 9
KG - Kirghizistan 9
NG - Nigeria 9
UY - Uruguay 9
GR - Grecia 7
RS - Serbia 7
SN - Senegal 7
EG - Egitto 6
LB - Libano 6
PS - Palestinian Territory 6
BG - Bulgaria 5
BH - Bahrain 5
BY - Bielorussia 5
DO - Repubblica Dominicana 5
OM - Oman 5
BW - Botswana 4
GA - Gabon 4
KH - Cambogia 4
KW - Kuwait 4
LA - Repubblica Popolare Democratica del Laos 4
LU - Lussemburgo 4
LV - Lettonia 4
PA - Panama 4
AF - Afghanistan, Repubblica islamica di 3
BA - Bosnia-Erzegovina 3
CG - Congo 3
EU - Europa 3
GT - Guatemala 3
HR - Croazia 3
LK - Sri Lanka 3
MN - Mongolia 3
MT - Malta 3
Totale 43.817
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Città #
Helsinki 5.818
Singapore 2.586
Ashburn 2.058
Fairfield 1.429
Woodbridge 1.423
Dallas 1.281
San Jose 1.263
Chandler 991
Houston 956
Santa Clara 945
Beijing 913
Jacksonville 815
Hong Kong 800
Ann Arbor 719
Seattle 615
Wilmington 557
Cambridge 474
Ho Chi Minh City 415
Ferrara 399
New York 338
Los Angeles 319
Hanoi 318
Munich 317
Izmir 309
Warsaw 288
Tokyo 286
Nanjing 256
Princeton 233
Council Bluffs 226
Lauterbourg 196
Boardman 162
Shanghai 161
Jakarta 150
Milan 150
San Diego 135
São Paulo 129
Orem 117
Dearborn 109
Bremen 105
Mexico City 105
Nanchang 84
London 82
The Dalles 77
Montreal 74
Brussels 73
Shenyang 73
Tianjin 70
Toronto 65
Brooklyn 64
Falls Church 60
Chennai 59
Chicago 58
Denver 58
Buffalo 57
Da Nang 57
Frankfurt am Main 57
Jiaxing 57
Johannesburg 56
Atlanta 55
Redwood City 54
Changsha 52
Hefei 51
Moscow 48
Poplar 48
Hebei 45
Rio de Janeiro 45
Tashkent 44
Haiphong 43
Jinan 43
Stockholm 41
Guangzhou 40
Phoenix 40
Turku 39
Manchester 38
Baghdad 37
Bologna 37
San Mateo 37
Amsterdam 36
Falkenstein 36
Mountain View 35
Belo Horizonte 33
Curitiba 33
Dong Ket 33
Nuremberg 32
Kunming 30
Norwalk 30
Rome 29
San Francisco 29
Des Moines 28
Mumbai 28
Paris 28
Ankara 26
Biên Hòa 26
Nairobi 25
Auburn Hills 24
Ningbo 24
Zhengzhou 24
Brno 23
Columbus 23
Campinas 22
Totale 31.541
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Nome #
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.855
A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients 2.050
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2.043
Differential functional readthrough over homozygous nonsense mutations contributes to the bleeding phenotype in coagulation factor VII deficiency 300
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 297
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth 297
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 294
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 291
An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes 285
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 278
Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings 273
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates 259
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 257
VITAMIN K-INDUCED MODIFICATION OF COAGULATION PHENOTYPE IN VKORC1 HOMOZYGOUS DEFICIENCY 247
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 246
Transposon-mediated Generation of Cellular and Mouse Models of Splicing Mutations to Assess the Efficacy of snRNA-based Therapeutics 242
Responsiveness of hemophilia B- causing non sense mutations to ribosome readthrough-inducing drugs strictly depends on the nucleotide and prrotein context 241
Attività sulla emostasi di alcune piante della medicina tradizionale indiana 238
Chronic sleep deprivation markedly reduces coagulation factor VII expression 237
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 237
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 236
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 234
Factor XIII-A dynamics in acute myocardial infarction: a novel prognostic biomarker? 233
Membrane binding and anticoagulant properties of protein S natural variants 232
Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts 232
Nuove strategie per la veicolazione di acidi nucleici: nanosistemi cationici a matrice lipidica 230
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 228
Cationic lipid nanosystems as carriers for nucleic acids 228
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 228
Daily and circadian rhythms of tissue factor pathway inhibitor and factor VII activity 223
Evidence for an overlapping role of clock and npas2 transcription factors in liver circadian oscillators 221
The carboxyl-terminal region is not essential for secreted and functional levels of coagulation factor X 219
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 217
Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster 216
Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model 214
Mutation pattern in clinically asymptomatic coagulation factor VII deficiency 212
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 212
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis 210
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 210
Effective hemostasis during minor surgery in a case of hereditary combined deficiency of vitamin K-dependent clotting factors 208
FXIII levels and genotypes in myocardial infarction: a potential novel prognostic biomarker? 206
Molecular bases of type II protein S deficiency: the I203-D204 deletion in the EGF4 domain alters GLA domain function 204
Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation 204
Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile 203
The carboxyl-terminal region is NOT essential for secreted and functional levels of coagulation factor X 203
The dominant-negative von Willebrand factor gene deletion p.P1127-C1948delinsR: Molecular mechanism and modulation 203
Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition 203
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations 202
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene 200
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics 198
The factor V Glu1608Lys mutation is recurrent in familial thrombophilia 197
Ribosome readthrough accounts for secreted full-length factor IX in hemophilia B patients with nonsense mutations 197
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. 196
Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glul02Lys) in the second EGF‐like domain 195
Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency 195
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 195
Cationic lipid nanosystems as carriers for nucleic acids 194
Residual factor VII activity and different hemorrhagic phenotypes in CRM+ factor VII deficiencies (Gly331Ser and Gly283Ser) 192
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 192
Circadian rhythms in mouse blood coagulation 190
Temporal variations of coagulation factor VII activity in mice are influenced by lighting regime 189
Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency 187
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 186
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 184
Factor VII mutant V154G models a zymogen-like form of factor VIIa 183
Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity 183
Modulation of factor VII levels by intron 7 polymorphisms: Population and in vitro studies 182
Molecular mechanisms of FVII deficiency: Expression of mutations clustered in the IVS7 donor splice site of factor VII gene 181
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 180
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 180
Nanosistemi lipidici per la veicolazione di acidi nucleici 179
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. 178
Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity 178
Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis 178
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency 178
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 177
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 176
CRISPR activation on coagulation F7 or F8 promoters potentiate trascriptional activity in the normal and mutated gene context 176
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 175
Association of the homozygous nonsense mutation R402X in coagulation factor VII with asymptomatic phenotype 175
Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA 174
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 174
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 173
Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII 173
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 172
Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma 170
Cationic nanostructured lipid carrier (NLC) and monoolein aqueous dispersions (MAD) as potential carriers for nucleic acids 170
Rescue of coagulation factor VII function by the U1+5A snRNA 170
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors 169
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 166
Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease 165
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity 164
Detection and characterization of polymorphic markers in the factor-VII gene. 163
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 162
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 162
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 162
Contribution of factor VII genotype to activated FVII levels: Differences in genotype frequencies between northern and southern European populations 161
Characterization of PAR-mediated signaling induced by activated coagulation factor X mutants 161
A next-generation rFVIIa fusion protein with enhanced half-life as a novel by-passing tool in hemophilia 161
In-Frame Deletion of von Willebrand Factor Exons 26-34 (D3-A3 Domains) in Type II von Willebrand Disease. 160
Totale 26.816
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Categoria #
all - tutte 172.309
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.192
Totale 173.501
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021967 0 0 0 0 0 0 0 0 0 454 366 147
2021/20222.248 137 262 114 73 113 104 112 106 80 187 185 775
2022/20232.359 261 184 73 301 409 315 135 179 276 15 128 83
2023/20241.269 110 140 79 45 79 210 50 77 36 48 40 355
2024/20255.698 175 117 507 179 696 710 172 233 886 585 781 657
2025/202621.550 1.530 905 1.944 2.153 2.378 1.073 1.986 921 6.992 1.668 0 0
Totale 44.381