PINOTTI, Mirko
PINOTTI, Mirko
Dipartimento di Scienze della vita e biotecnologie
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects
2023 Pedriali, G.; Ramaccini, D.; Bouhamida, E.; Branchini, A.; Turrin, G.; Tonet, E.; Scala, A.; Patergnani, S.; Pinotti, M.; Trapella, C.; Giorgi, C.; Tremoli, E.; Campo, G.; Morciano, G.; Pinton, P.
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I
2020 Balestra, Dario; Scalet, Daniela; Ferrarese, Mattia; Lombardi, Silvia; Ziliotto, Nicole; C. Croes, Chrystal; Petersen, Naomi; Bosma, Piter; Riccardi, Federico; Pagani, Franco; Pinotti, Mirko; van de Graaf, Stan F. J.
A factor X variant with engineered activation peptide as innovative by-passing agent for haemophilia
file con accesso da definire2022 Tonetto, E.; Tarantino, R.; Testa, M. F.; Peretto, L.; Bernardi, F.; Pinotti, M.; Branchini, A.
A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates.
file con accesso da definire2002 Toso, Raffaella; Pinotti, Mirko; High, Ka; Pollak, Es; Bernardi, Francesco
A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients
2021 Morciano, G.; Pedriali, G.; Bonora, M.; Pavasini, R.; Mikus, E.; Calvi, S.; Bovolenta, M.; Lebiedzinska-Arciszewska, M.; Pinotti, M.; Albertini, A.; Wieckowski, M. R.; Giorgi, C.; Ferrari, R.; Galluzzi, L.; Campo, G.; Pinton, P.
A new type 1 von Willebrand Disease (VWD) characterized by increased clearance of von Willebrand Factor (VWF) due to the heterozygous p.P1127S mutation: clinical phenotype and pathogenic mechanisms
file con accesso da definire2022 M. Sacco, M. Tardugno; De Cristofaro, R.; Lancellotti, S.; Bernardi, F.; Pinotti, M.; Branchini, A.; Giusti, B.; Castaman, G.
A next-generation rFVIIa fusion protein with enhanced half-life as a novel by-passing tool in hemophilia
2020 Branchini, Alessio; Ferrarese, Mattia; Nilsen, Jeannette; Bern, Malin; Davidson, Robert J.; Camire, Rodney M.; Roopenian, Derry C.; Sandlie, Inger; Lombardi, Silvia; Terje Andersen, Jan; Pinotti, Mirko
A novel tailored correction approach for recurrent hemophilia-causing nonsense mutations through AntiCodon-Engineered suppressor tRNAs
file con accesso da definire2023 Testa, Maria Francesca; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
A recoded view on the F9 p.Cys178Ter pathogenic mechanism
2020 Branchini, A.; Pinotti, M.
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B
2018 Pignani, Silvia; Todaro, Alice; Ferrarese, Mattia; Marchi, Saverio; Lombardi, Silvia; Balestra, Dario; Pinton, Paolo; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice
file con accesso da definire2015 Balestra, Dario; Scalet, Daniela; Pagani, Franco; Bernardi, Francesco; Pinotti, Mirko
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene
file con accesso da definire2013 M., Menegatti; Balestra, Dario; B., Fabrizzi; R., Asselta; Pinotti, Mirko; F., Peyvandi
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation
file con accesso da definire2011 Cavallari, Nicola; Balestra, Dario; Rizzotto, Lara; Maestri, Iva; A., Chamsunri; Bernardi, Francesco; Pinotti, Mirko
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant
file con accesso da definire2012 Cavallari, Nicola; Balestra, Dario; Branchini, Alessio; Maestri, Iva; Chuamsunrit, A; Sasanakul, W; Mariani, G; Pagani, F; Bernardi, Francesco; Pinotti, Mirko
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency
2018 Andersen, Elisabeth; Chollet, Maria Eugenia; Myklebust, Christiane Filion; Pinotti, Mirko; Bernardi, Francesco; Chuansumrit, Ampaiwan; Skarpen, Ellen; Sandset, Per Morten; Skretting, Grethe
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene
file con accesso da definire2001 Ferrara, Rossella; Mastrorilli, Francesca; Bressan, Sabrina; Ferraresi, Paolo; Gemmati, Donato; Tognazzo, Silvia; Pinotti, Mirko; Scapoli, Gian Luigi; Bernardi, Francesco; Ferrari, Roberto
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth
2019 Marchi, Saverio; Corricelli, Mariangela; Branchini, Alessio; Vitto, VERONICA ANGELA MARIA; Missiroli, Sonia; Morciano, Giampaolo; Perrone, Mariasole; Ferrarese, Mattia; Giorgi, Carlotta; Pinotti, Mirko; Galluzzi, Lorenzo; Kroemer, Guido; Pinton, Paolo
Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients.
file con accesso da definire2014 Donadon, Irving; Pinotti, Mirko
An advanced method for the small-scale production of high-quality minicircle DNA
2021 Mitdank, Hardy; Sama, Simko; Tröger, Meike; Testa, Maria Francesca; Ferrarese, Mattia; Balestra, Dario; Pinotti, Mirko; Weng, Alexander
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A
2019 Balestra, Dario; Maestri, Iva; Branchini, Alessio; Ferrarese, Mattia; Bernardi, Francesco; Pinotti, Mirko
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects | 2023 | Pedriali, G.; Ramaccini, D.; Bouhamida, E.; Branchini, A.; Turrin, G.; Tonet, E.; Scala, A.; Pate...rgnani, S.; Pinotti, M.; Trapella, C.; Giorgi, C.; Tremoli, E.; Campo, G.; Morciano, G.; Pinton, P. | |
| A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I | 2020 | Balestra, Dario; Scalet, Daniela; Ferrarese, Mattia; Lombardi, Silvia; Ziliotto, Nicole; C. Croes..., Chrystal; Petersen, Naomi; Bosma, Piter; Riccardi, Federico; Pagani, Franco; Pinotti, Mirko; van de Graaf, Stan F. J. | |
| A factor X variant with engineered activation peptide as innovative by-passing agent for haemophilia | 2022 | Tonetto, E.; Tarantino, R.; Testa, M. F.; Peretto, L.; Bernardi, F.; Pinotti, M.; Branchini, A. | file con accesso da definire |
| A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates. | 2002 | Toso, Raffaella; Pinotti, Mirko; High, Ka; Pollak, Es; Bernardi, Francesco | file con accesso da definire |
| A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients | 2021 | Morciano, G.; Pedriali, G.; Bonora, M.; Pavasini, R.; Mikus, E.; Calvi, S.; Bovolenta, M.; Lebied...zinska-Arciszewska, M.; Pinotti, M.; Albertini, A.; Wieckowski, M. R.; Giorgi, C.; Ferrari, R.; Galluzzi, L.; Campo, G.; Pinton, P. | |
| A new type 1 von Willebrand Disease (VWD) characterized by increased clearance of von Willebrand Factor (VWF) due to the heterozygous p.P1127S mutation: clinical phenotype and pathogenic mechanisms | 2022 | M. Sacco, M. Tardugno; De Cristofaro, R.; Lancellotti, S.; Bernardi, F.; Pinotti, M.; Branchini, ...A.; Giusti, B.; Castaman, G. | file con accesso da definire |
| A next-generation rFVIIa fusion protein with enhanced half-life as a novel by-passing tool in hemophilia | 2020 | Branchini, Alessio; Ferrarese, Mattia; Nilsen, Jeannette; Bern, Malin; Davidson, Robert J.; Camir...e, Rodney M.; Roopenian, Derry C.; Sandlie, Inger; Lombardi, Silvia; Terje Andersen, Jan; Pinotti, Mirko | |
| A novel tailored correction approach for recurrent hemophilia-causing nonsense mutations through AntiCodon-Engineered suppressor tRNAs | 2023 | Testa, Maria Francesca; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio | file con accesso da definire |
| A recoded view on the F9 p.Cys178Ter pathogenic mechanism | 2020 | Branchini, A.; Pinotti, M. | |
| A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B | 2018 | Pignani, Silvia; Todaro, Alice; Ferrarese, Mattia; Marchi, Saverio; Lombardi, Silvia; Balestra, D...ario; Pinton, Paolo; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio | |
| A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice | 2015 | Balestra, Dario; Scalet, Daniela; Pagani, Franco; Bernardi, Francesco; Pinotti, Mirko | file con accesso da definire |
| A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene | 2013 | M., Menegatti; Balestra, Dario; B., Fabrizzi; R., Asselta; Pinotti, Mirko; F., Peyvandi | file con accesso da definire |
| Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation | 2011 | Cavallari, Nicola; Balestra, Dario; Rizzotto, Lara; Maestri, Iva; A., Chamsunri; Bernardi, France...sco; Pinotti, Mirko | file con accesso da definire |
| Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant | 2012 | Cavallari, Nicola; Balestra, Dario; Branchini, Alessio; Maestri, Iva; Chuamsunrit, A; Sasanakul, ...W; Mariani, G; Pagani, F; Bernardi, Francesco; Pinotti, Mirko | file con accesso da definire |
| Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency | 2018 | Andersen, Elisabeth; Chollet, Maria Eugenia; Myklebust, Christiane Filion; Pinotti, Mirko; Bernar...di, Francesco; Chuansumrit, Ampaiwan; Skarpen, Ellen; Sandset, Per Morten; Skretting, Grethe | |
| Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene | 2001 | Ferrara, Rossella; Mastrorilli, Francesca; Bressan, Sabrina; Ferraresi, Paolo; Gemmati, Donato; T...ognazzo, Silvia; Pinotti, Mirko; Scapoli, Gian Luigi; Bernardi, Francesco; Ferrari, Roberto | file con accesso da definire |
| Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth | 2019 | Marchi, Saverio; Corricelli, Mariangela; Branchini, Alessio; Vitto, VERONICA ANGELA MARIA; Missir...oli, Sonia; Morciano, Giampaolo; Perrone, Mariasole; Ferrarese, Mattia; Giorgi, Carlotta; Pinotti, Mirko; Galluzzi, Lorenzo; Kroemer, Guido; Pinton, Paolo | |
| Altered mRNA processing and FVIII biosynthesis/function as determinants of phenotype variability in the frequent Arg2016Trp Haemophilia A patients. | 2014 | Donadon, Irving; Pinotti, Mirko | file con accesso da definire |
| An advanced method for the small-scale production of high-quality minicircle DNA | 2021 | Mitdank, Hardy; Sama, Simko; Tröger, Meike; Testa, Maria Francesca; Ferrarese, Mattia; Balestra, ...Dario; Pinotti, Mirko; Weng, Alexander | |
| An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A | 2019 | Balestra, Dario; Maestri, Iva; Branchini, Alessio; Ferrarese, Mattia; Bernardi, Francesco; Pinott...i, Mirko |