We investigated in patients with ongoing myocardial infarction (MI) whether coagulation factor VII (FVII) and tissue factor (TF) levels are affected at admission by genetic components and whether they may predict subsequent cardiovascular events. Admission FVII and TF antigen levels, partially predicted by polymorphisms, are independent predictors of mortality and reinfarction in patients with acute MI.
Acute Coronaric Syndroms and FVII polymorphisms: different effects in the same gene
FERRARA, Rossella;MASTRORILLI, Francesca;BRESSAN, Sabrina;FERRARESI, Paolo;GEMMATI, Donato;TOGNAZZO, Silvia;PINOTTI, Mirko;SCAPOLI, Gian Luigi;BERNARDI, Francesco;FERRARI, Roberto
2001
Abstract
We investigated in patients with ongoing myocardial infarction (MI) whether coagulation factor VII (FVII) and tissue factor (TF) levels are affected at admission by genetic components and whether they may predict subsequent cardiovascular events. Admission FVII and TF antigen levels, partially predicted by polymorphisms, are independent predictors of mortality and reinfarction in patients with acute MI.File in questo prodotto:
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