TRAPELLA, Claudio
 Distribuzione geografica
Continente #
NA - Nord America 10.286
EU - Europa 3.140
AS - Asia 2.103
SA - Sud America 27
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 4
AF - Africa 1
Totale 15.567
Nazione #
US - Stati Uniti d'America 10.221
IT - Italia 987
CN - Cina 984
SG - Singapore 527
UA - Ucraina 474
DE - Germania 437
GB - Regno Unito 366
TR - Turchia 319
PL - Polonia 235
SE - Svezia 219
FI - Finlandia 146
VN - Vietnam 111
BE - Belgio 94
ID - Indonesia 89
CA - Canada 62
FR - Francia 36
CZ - Repubblica Ceca 27
RU - Federazione Russa 26
NL - Olanda 21
IN - India 17
LT - Lituania 16
IR - Iran 15
NO - Norvegia 13
ES - Italia 12
HK - Hong Kong 12
JP - Giappone 11
BR - Brasile 9
BG - Bulgaria 7
CO - Colombia 7
AU - Australia 6
CL - Cile 4
EU - Europa 4
IE - Irlanda 4
KR - Corea 4
AR - Argentina 3
AT - Austria 3
PE - Perù 3
PT - Portogallo 3
RO - Romania 3
TH - Thailandia 3
CH - Svizzera 2
CR - Costa Rica 2
DK - Danimarca 2
NP - Nepal 2
SM - San Marino 2
AE - Emirati Arabi Uniti 1
GR - Grecia 1
HU - Ungheria 1
IQ - Iraq 1
KG - Kirghizistan 1
KW - Kuwait 1
LU - Lussemburgo 1
MA - Marocco 1
MY - Malesia 1
PA - Panama 1
PH - Filippine 1
PK - Pakistan 1
SA - Arabia Saudita 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 15.567
Città #
Fairfield 1.351
Woodbridge 1.219
Ann Arbor 801
Houston 766
Ashburn 759
Chandler 672
Seattle 573
Jacksonville 553
Wilmington 523
Cambridge 468
Singapore 434
Ferrara 376
Santa Clara 351
Beijing 238
Warsaw 235
Izmir 198
Nanjing 173
Princeton 154
Shanghai 127
Milan 122
Boardman 112
Dong Ket 106
New York 101
San Diego 101
Brussels 89
Jakarta 89
Los Angeles 70
Munich 62
Dearborn 60
Shenyang 51
Nanchang 50
Addison 46
Helsinki 45
London 45
Bremen 43
Bologna 39
Falls Church 36
Redwood City 35
Jiaxing 33
Hebei 32
Tianjin 32
Auburn Hills 31
Mcallen 26
Toronto 26
Mountain View 25
Norwalk 25
Changsha 24
San Mateo 24
Washington 21
Montréal 20
Brno 18
Zhengzhou 18
Ferrara di Monte Baldo 17
Jinan 16
Des Moines 15
Philadelphia 15
Rome 15
Tappahannock 14
Kunming 13
Oslo 13
Frankfurt am Main 12
Leawood 12
Ottawa 12
Amsterdam 11
Guangzhou 11
Ningbo 11
Padova 10
San Jose 9
Hong Kong 8
Indiana 8
Orange 8
Redmond 8
Tyler 8
Augusta 7
Hangzhou 7
Hefei 7
Imola 7
Lanzhou 7
Medellín 7
Olomouc 7
Taizhou 7
Ardabil 6
Chicago 6
Fossò 6
Islington 6
Napoli 6
Parma 6
Reggio Emilia 6
Tokyo 6
Chiswick 5
Dozza 5
Haikou 5
Modena 5
San Francisco 5
Andover 4
Arezzo 4
Boulder 4
Brescia 4
Castenaso 4
Catania 4
Totale 12.027
Nome #
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles 240
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 236
null 214
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 192
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence 190
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice 186
Design and synthesis of99mTcN-labeled dextran-mannose derivatives for sentinel lymph node detection 184
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 175
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 171
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 169
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 168
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 161
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 161
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor 153
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide. 151
Physicochemical stability of cabazitaxel and docetaxel solutions 149
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice 148
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 146
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 146
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 145
C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors 143
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 142
Letter to the Editor: Antimicrobial properties of mucus from the brown garden snail Helix aspersa 141
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 141
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 140
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 138
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 138
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity 136
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 134
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 133
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors 133
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 132
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 130
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 129
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway 128
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains 126
Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors 125
Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic G i/o protein linked pathways 124
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 124
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor 123
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: Pharmacological and genetic evidences 122
A new synthetic approach to 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-benzimidazol-2-one (J-113397), the first non-peptide ORL-1 receptor antagonist 121
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity 120
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice 120
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 120
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 119
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24. 119
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 118
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists. 118
Synthesis and proteasome inhibition of N-allyl vinyl ester-based peptides 117
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 117
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors 116
Structure-activity study at positions 3 and 4 of human neuropeptide S. 116
JWH-018 impairs sensorimotor functions in mice 115
Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine-lactone induces HLA-G expression in human immune cells 115
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 114
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 113
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT 113
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor. 112
Role of benzimidazole (Bid) in the d-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH2-Bid (UFP-502) 112
Recent advances in the stereoselective synthesis of trans-3,4- disubstituted-piperidines: applications to (-)paroxetine 112
Sviluppo di un Sistema combinato a filiera controllata per l’allevamento, l’estrazione, la caratterizzazione e la sanificazione del secreto di chiocciola 112
Helix aspersa muller mucus (Helixcomplex ®) interferes with Herpes simplex 1 virus infection 111
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 110
null 110
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 109
Neuropeptide S receptor ligands: a patent review (2005-2016) 109
A Convenient Route to Enantiomerically Pure 2-Substituted Methyl Glycerate Derivatives 107
null 107
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 107
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists. 106
Synthesis and activity of isoxazoline vinyl ester pseudopeptides as proteasome inhibitors. 105
null 105
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting thefolate pathway 104
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl] methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vitro studies 104
Synthesis and biological properties of C-terminal vinyl ketone pseudotripeptides 102
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 101
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids 101
Neuropeptide S inhibits release of 5-HT and glycine in mouse amygdala and frontal/prefrontal cortex through activation of the neuropeptide S receptor. 100
Mastering chiral substituted 2-oxopiperazines 99
Modulation of Silent and Constitutively Active Nociceptin/Orphanin FQ Receptors by Potent Receptor Antagonists and Na+ Ions in Rat Sympathetic Neurons. 99
NOP receptor pharmacological profile – A dynamic mass redistribution study 98
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 97
Triazine Compounds as Antagonists at Bv8-Prokineticin Receptors 97
A linear allergic contact dermatitis to p-tert-butylphenol formaldehyde resin sectorially present in a neoprene orthopedic brace: role of spectroscopy 97
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 97
null 96
null 96
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore 95
null 94
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Galpha(qi5). 94
Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test 94
null 94
Anxiolytic and antidepressant-like activities of UFP-512, a novel selective delta opiold receptor agonist 92
Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice 92
Influence of the Side Chain Next to C-Terminal Benzimidazole in Opioid Pseudopeptides Containing the Dmt-Tic Pharmacophore 90
Helix aspersa muller mucus (Helixcomplex ®) p41 protein prevents Pseudomonas aeruginosa growth and promotes mammalian bronchial epithelial cell proliferation 89
null 88
A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity 88
null 87
Totale 12.477
Categoria #
all - tutte 76.611
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 337
Totale 76.948


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.094 0 0 0 0 246 381 320 319 280 277 181 90
2020/20212.551 151 196 124 232 131 204 169 304 116 400 284 240
2021/20221.780 107 169 150 104 138 68 123 99 75 134 165 448
2022/20231.779 180 156 70 207 254 202 110 158 227 18 111 86
2023/20241.279 90 121 90 37 92 227 74 109 38 49 44 308
2024/20251.367 112 123 405 256 471 0 0 0 0 0 0 0
Totale 15.911