TRAPELLA, Claudio
 Distribuzione geografica
Continente #
NA - Nord America 9.904
EU - Europa 2.981
AS - Asia 1.925
SA - Sud America 27
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 4
AF - Africa 1
Totale 14.848
Nazione #
US - Stati Uniti d'America 9.872
CN - Cina 942
IT - Italia 933
UA - Ucraina 474
DE - Germania 415
SG - Singapore 394
GB - Regno Unito 342
TR - Turchia 319
PL - Polonia 235
SE - Svezia 219
FI - Finlandia 136
VN - Vietnam 111
ID - Indonesia 89
BE - Belgio 82
FR - Francia 36
CA - Canada 29
CZ - Repubblica Ceca 27
RU - Federazione Russa 26
NL - Olanda 16
IN - India 15
IR - Iran 15
HK - Hong Kong 12
ES - Italia 11
JP - Giappone 11
BR - Brasile 9
BG - Bulgaria 7
CO - Colombia 7
AU - Australia 6
CL - Cile 4
EU - Europa 4
IE - Irlanda 4
KR - Corea 4
AR - Argentina 3
AT - Austria 3
PE - Perù 3
PT - Portogallo 3
RO - Romania 3
TH - Thailandia 3
CR - Costa Rica 2
DK - Danimarca 2
NP - Nepal 2
SM - San Marino 2
AE - Emirati Arabi Uniti 1
GR - Grecia 1
HU - Ungheria 1
IQ - Iraq 1
KG - Kirghizistan 1
KW - Kuwait 1
LU - Lussemburgo 1
MA - Marocco 1
MY - Malesia 1
PA - Panama 1
PH - Filippine 1
PK - Pakistan 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 14.848
Città #
Fairfield 1.351
Woodbridge 1.219
Ann Arbor 801
Houston 766
Ashburn 759
Chandler 672
Seattle 573
Jacksonville 553
Wilmington 523
Cambridge 468
Ferrara 350
Singapore 305
Beijing 238
Warsaw 235
Izmir 198
Nanjing 173
Princeton 154
Shanghai 127
Milan 121
Boardman 112
Dong Ket 106
New York 101
San Diego 101
Jakarta 89
Brussels 77
Los Angeles 68
Dearborn 60
Shenyang 51
Munich 50
Nanchang 50
Santa Clara 49
Addison 46
Bremen 43
Bologna 36
Falls Church 36
Helsinki 35
Redwood City 35
Jiaxing 33
Hebei 32
Tianjin 32
Auburn Hills 31
London 26
Mcallen 26
Mountain View 25
Norwalk 25
Changsha 24
San Mateo 24
Washington 21
Montréal 20
Brno 18
Zhengzhou 18
Ferrara di Monte Baldo 17
Jinan 16
Des Moines 15
Philadelphia 15
Rome 15
Tappahannock 14
Kunming 13
Leawood 12
Amsterdam 11
Guangzhou 11
Ningbo 11
Padova 10
San Jose 9
Hong Kong 8
Indiana 8
Orange 8
Redmond 8
Tyler 8
Augusta 7
Hangzhou 7
Hefei 7
Imola 7
Lanzhou 7
Medellín 7
Olomouc 7
Taizhou 7
Ardabil 6
Chicago 6
Fossò 6
Islington 6
Napoli 6
Parma 6
Reggio Emilia 6
Tokyo 6
Chiswick 5
Haikou 5
Modena 5
San Francisco 5
Andover 4
Arezzo 4
Boulder 4
Brescia 4
Castenaso 4
Catania 4
Changchun 4
Dublin 4
Fuzhou 4
La Canada Flintridge 4
Naples 4
Totale 11.463
Nome #
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles 236
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 228
null 214
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence 185
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice 183
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 183
Design and synthesis of99mTcN-labeled dextran-mannose derivatives for sentinel lymph node detection 180
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 171
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 166
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 164
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 162
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 156
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 156
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor 148
Physicochemical stability of cabazitaxel and docetaxel solutions 147
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide. 146
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice 142
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 141
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 141
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 140
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 140
Letter to the Editor: Antimicrobial properties of mucus from the brown garden snail Helix aspersa 138
C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors 137
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 136
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 134
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity 134
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 134
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 130
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 130
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors 130
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 130
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 126
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway 126
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 126
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 125
Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors 122
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 121
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains 121
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor 121
Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic G i/o protein linked pathways 120
A new synthetic approach to 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-benzimidazol-2-one (J-113397), the first non-peptide ORL-1 receptor antagonist 118
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 117
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice 117
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 117
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: Pharmacological and genetic evidences 116
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 116
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity 116
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24. 116
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists. 115
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors 114
Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine-lactone induces HLA-G expression in human immune cells 113
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 112
Structure-activity study at positions 3 and 4 of human neuropeptide S. 112
JWH-018 impairs sensorimotor functions in mice 112
Synthesis and proteasome inhibition of N-allyl vinyl ester-based peptides 112
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 111
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor. 110
Role of benzimidazole (Bid) in the d-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH2-Bid (UFP-502) 110
null 110
Recent advances in the stereoselective synthesis of trans-3,4- disubstituted-piperidines: applications to (-)paroxetine 109
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT 109
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 107
null 107
Sviluppo di un Sistema combinato a filiera controllata per l’allevamento, l’estrazione, la caratterizzazione e la sanificazione del secreto di chiocciola 107
Neuropeptide S receptor ligands: a patent review (2005-2016) 107
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 106
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 105
null 105
A Convenient Route to Enantiomerically Pure 2-Substituted Methyl Glycerate Derivatives 104
Helix aspersa muller mucus (Helixcomplex ®) interferes with Herpes simplex 1 virus infection 104
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 103
Synthesis and activity of isoxazoline vinyl ester pseudopeptides as proteasome inhibitors. 102
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting thefolate pathway 101
Synthesis and biological properties of C-terminal vinyl ketone pseudotripeptides 100
Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists. 99
Neuropeptide S inhibits release of 5-HT and glycine in mouse amygdala and frontal/prefrontal cortex through activation of the neuropeptide S receptor. 98
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 97
Modulation of Silent and Constitutively Active Nociceptin/Orphanin FQ Receptors by Potent Receptor Antagonists and Na+ Ions in Rat Sympathetic Neurons. 97
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl] methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vitro studies 97
null 96
Mastering chiral substituted 2-oxopiperazines 96
null 96
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids 96
Triazine Compounds as Antagonists at Bv8-Prokineticin Receptors 95
null 94
NOP receptor pharmacological profile – A dynamic mass redistribution study 94
null 94
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore 93
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Galpha(qi5). 91
A linear allergic contact dermatitis to p-tert-butylphenol formaldehyde resin sectorially present in a neoprene orthopedic brace: role of spectroscopy 89
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 89
null 88
Influence of the Side Chain Next to C-Terminal Benzimidazole in Opioid Pseudopeptides Containing the Dmt-Tic Pharmacophore 88
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 87
null 87
null 87
Anxiolytic and antidepressant-like activities of UFP-512, a novel selective delta opiold receptor agonist 87
Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice 87
Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test 86
Helix aspersa muller mucus (Helixcomplex ®) p41 protein prevents Pseudomonas aeruginosa growth and promotes mammalian bronchial epithelial cell proliferation 84
Totale 12.102
Categoria #
all - tutte 69.987
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 311
Totale 70.298


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.522 0 0 0 428 246 381 320 319 280 277 181 90
2020/20212.551 151 196 124 232 131 204 169 304 116 400 284 240
2021/20221.780 107 169 150 104 138 68 123 99 75 134 165 448
2022/20231.779 180 156 70 207 254 202 110 158 227 18 111 86
2023/20241.279 90 121 90 37 92 227 74 109 38 49 44 308
2024/2025643 112 123 405 3 0 0 0 0 0 0 0 0
Totale 15.187