TRAPELLA, Claudio
 Distribuzione geografica
Continente #
NA - Nord America 16.983
EU - Europa 9.312
AS - Asia 8.368
SA - Sud America 1.208
AF - Africa 194
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 9
Totale 36.089
Nazione #
US - Stati Uniti d'America 16.586
FI - Finlandia 4.188
SG - Singapore 3.176
CN - Cina 2.087
IT - Italia 1.374
DE - Germania 1.056
VN - Vietnam 1.040
BR - Brasile 951
HK - Hong Kong 698
GB - Regno Unito 593
UA - Ucraina 525
TR - Turchia 381
PL - Polonia 322
FR - Francia 280
SE - Svezia 269
JP - Giappone 233
CA - Canada 211
RU - Federazione Russa 194
IN - India 166
ID - Indonesia 138
MX - Messico 138
BD - Bangladesh 102
BE - Belgio 102
NL - Olanda 101
AR - Argentina 91
ZA - Sudafrica 70
ES - Italia 61
IQ - Iraq 60
LT - Lituania 47
PK - Pakistan 46
AT - Austria 43
CZ - Repubblica Ceca 41
EC - Ecuador 36
VE - Venezuela 35
SA - Arabia Saudita 34
CO - Colombia 29
MA - Marocco 25
MY - Malesia 22
UZ - Uzbekistan 22
CL - Cile 21
TN - Tunisia 21
IE - Irlanda 20
PH - Filippine 20
IR - Iran 17
NP - Nepal 15
PE - Perù 15
JO - Giordania 14
KE - Kenya 14
KR - Corea 14
NO - Norvegia 14
BG - Bulgaria 13
DZ - Algeria 13
EG - Egitto 13
PY - Paraguay 13
AU - Australia 12
TW - Taiwan 12
AE - Emirati Arabi Uniti 10
KZ - Kazakistan 10
DO - Repubblica Dominicana 9
CR - Costa Rica 8
UY - Uruguay 8
BO - Bolivia 7
CH - Svizzera 7
IL - Israele 7
JM - Giamaica 7
RO - Romania 7
SY - Repubblica araba siriana 7
AL - Albania 6
HN - Honduras 6
LV - Lettonia 6
NG - Nigeria 6
DK - Danimarca 5
KW - Kuwait 5
LB - Libano 5
PT - Portogallo 5
SN - Senegal 5
XK - ???statistics.table.value.countryCode.XK??? 5
ET - Etiopia 4
EU - Europa 4
GR - Grecia 4
HU - Ungheria 4
KG - Kirghizistan 4
OM - Oman 4
PA - Panama 4
RS - Serbia 4
TH - Thailandia 4
TT - Trinidad e Tobago 4
BH - Bahrain 3
GT - Guatemala 3
LY - Libia 3
MD - Moldavia 3
MU - Mauritius 3
NI - Nicaragua 3
SI - Slovenia 3
AM - Armenia 2
AO - Angola 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
BY - Bielorussia 2
Totale 36.048
Città #
Helsinki 3.979
Singapore 2.048
Ashburn 1.978
Dallas 1.738
Fairfield 1.351
Woodbridge 1.219
San Jose 903
Ann Arbor 801
Houston 794
Beijing 754
Chandler 672
Hong Kong 671
Santa Clara 659
Seattle 585
Jacksonville 560
Munich 528
Wilmington 524
Ferrara 473
Cambridge 468
Warsaw 308
Ho Chi Minh City 292
New York 271
Los Angeles 254
Hanoi 229
Tokyo 201
Izmir 200
Nanjing 176
Council Bluffs 168
Princeton 154
Lauterbourg 151
Milan 149
Shanghai 135
Boardman 117
Dong Ket 106
Jakarta 101
San Diego 101
Brussels 96
São Paulo 94
London 93
The Dalles 93
Mexico City 91
Orem 91
Bologna 79
Turku 78
Buffalo 65
Da Nang 61
Montreal 61
Dearborn 60
Frankfurt am Main 60
Hefei 58
Shenyang 57
Toronto 56
Atlanta 53
Chicago 52
Nanchang 51
Amsterdam 50
Poplar 50
Brooklyn 49
Johannesburg 47
Moscow 47
Stockholm 47
Addison 46
Tianjin 46
Rio de Janeiro 45
Bremen 44
Chennai 44
Denver 44
Rome 41
Manchester 39
Falls Church 36
Haiphong 35
Redwood City 35
Jiaxing 33
Phoenix 33
San Francisco 33
Hebei 32
Auburn Hills 31
Boston 31
Falkenstein 31
Porto Alegre 29
Mcallen 26
Norwalk 26
Washington 26
Mountain View 25
Changsha 24
San Mateo 24
Belo Horizonte 22
Charlotte 20
Curitiba 20
Guangzhou 20
Lahore 20
Montréal 20
New Delhi 20
Ankara 19
Brno 19
Dublin 19
Hải Dương 19
Nuremberg 19
Philadelphia 19
Zhengzhou 19
Totale 26.591
Nome #
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 2.933
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.854
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice 407
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 402
A linear allergic contact dermatitis to p-tert-butylphenol formaldehyde resin sectorially present in a neoprene orthopedic brace: role of spectroscopy 338
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles 326
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 324
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 314
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8 ,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vivo studies 307
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence 293
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 291
Design and synthesis of99mTcN-labeled dextran-mannose derivatives for sentinel lymph node detection 287
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 285
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains 282
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 278
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 265
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice 264
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl 263
C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors 254
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 252
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 242
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 242
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 237
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 236
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 235
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4′-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide 234
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor 234
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 234
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 232
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 227
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 225
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 224
A new synthetic approach to 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-benzimidazol-2-one (J-113397), the first non-peptide ORL-1 receptor antagonist 223
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 221
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 221
Sviluppo di un Sistema combinato a filiera controllata per l’allevamento, l’estrazione, la caratterizzazione e la sanificazione del secreto di chiocciola 218
Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic G i/o protein linked pathways 217
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 216
Synthesis and proteasome inhibition of N-allyl vinyl ester-based peptides 214
null 214
Helix aspersa muller mucus (Helixcomplex ®) interferes with Herpes simplex 1 virus infection 213
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: Pharmacological and genetic evidences 212
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity 212
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors 212
Design of Nanosystems for the Delivery of Quorum Sensing Inhibitors: A Preliminary Study 212
Synthesis and activity of isoxazoline vinyl ester pseudopeptides as proteasome inhibitors 211
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl] methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vitro studies 211
Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test 211
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 211
Physicochemical stability of cabazitaxel and docetaxel solutions 210
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24 209
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 209
Letter to the Editor: Antimicrobial properties of mucus from the brown garden snail Helix aspersa 209
JWH-018 impairs sensorimotor functions in mice 208
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 207
Further studies at neuropeptide S position 5: Discovery of novel neuropeptide S receptor antagonists 206
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice 206
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT 206
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 204
Mastering chiral substituted 2-oxopiperazines 202
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 201
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 201
Neuropeptide S receptor ligands: a patent review (2005-2016) 199
HelixComplex snail mucus as a potential technology against O3 induced skin damage 198
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists 193
Structure-activity study at positions 3 and 4 of human neuropeptide S. 192
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids 192
A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity 189
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 188
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity 188
Chemoenzymatic Stereodivergent Synthesis of All the Possible Stereoisomers of the 2,3-Dimethylglyceric Acid Ethyl Ester 187
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway 185
Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice 185
Recent advances in the stereoselective synthesis of trans-3,4- disubstituted-piperidines: applications to (-)paroxetine 184
A Cationic Contrast Agent in X-ray Imaging of Articular Cartilage: Pre-Clinical Evaluation of Diffusion and Attenuation Properties 182
A Convenient Route to Enantiomerically Pure 2-Substituted Methyl Glycerate Derivatives 181
Glyceric Prodrug of Ursodeoxycholic Acid (UDCA): Novozym 435-Catalyzed Synthesis of UDCA-Monoglyceride 181
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting thefolate pathway 180
Anxiolytic and antidepressant-like activities of UFP-512, a novel selective delta opiold receptor agonist 180
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors 179
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5 179
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 178
NOP receptor pharmacological profile – A dynamic mass redistribution study 178
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor 177
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 176
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 176
Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine-lactone induces HLA-G expression in human immune cells 176
Enzymatic esterification as potential strategy to enhance the sorbic acid behavior as food and beverage preservative 175
Xylitol as a Hydrophilization Moiety for a Biocatalytically Synthesized Ibuprofen Prodrug 173
Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors 172
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist 171
6-N,N-dimethylamino-2,3-naphthalimide: A new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides 170
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 169
Helix aspersa muller mucus (Helixcomplex ®) p41 protein prevents Pseudomonas aeruginosa growth and promotes mammalian bronchial epithelial cell proliferation 169
A proteomic approach to investigate the mechanism of action of anticancer peptides 168
Synthesis of 2,6-Dimethyltyrosine-Like Amino Acids through Pinacolinamide-Enabled C-H Dimethylation of 4-Dibenzylamino Phenylalanine 168
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): Identification of a partial agonist of the UT receptor 166
Role of benzimidazole (Bid) in the d-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH2-Bid (UFP-502) 166
An alternative enzymatic route to the ergogenic ketone body ester (R)-3-hydroxybutyl (r)-3-hydroxybutyrate 166
Neuropeptide S inhibits release of 5-HT and glycine in mouse amygdala and frontal/prefrontal cortex through activation of the neuropeptide S receptor 165
Totale 27.149
Categoria #
all - tutte 136.570
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 637
Totale 137.207


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021924 0 0 0 0 0 0 0 0 0 400 284 240
2021/20221.780 107 169 150 104 138 68 123 99 75 134 165 448
2022/20231.779 180 156 70 207 254 202 110 158 227 18 111 86
2023/20241.279 90 121 90 37 92 227 74 109 38 49 44 308
2024/20254.834 112 123 405 256 487 459 281 306 861 388 632 524
2025/202617.086 1.427 835 2.202 1.576 1.824 869 1.583 745 4.802 1.223 0 0
Totale 36.464