TRAPELLA, Claudio
 Distribuzione geografica
Continente #
NA - Nord America 17.669
EU - Europa 9.459
AS - Asia 8.591
SA - Sud America 1.218
AF - Africa 194
OC - Oceania 16
Continente sconosciuto - Info sul continente non disponibili 9
Totale 37.156
Nazione #
US - Stati Uniti d'America 17.228
FI - Finlandia 4.191
SG - Singapore 3.217
CN - Cina 2.115
IT - Italia 1.495
DE - Germania 1.058
VN - Vietnam 1.040
BR - Brasile 956
HK - Hong Kong 714
GB - Regno Unito 595
UA - Ucraina 525
TR - Turchia 381
PL - Polonia 323
FR - Francia 283
SE - Svezia 270
CA - Canada 242
JP - Giappone 235
BD - Bangladesh 233
RU - Federazione Russa 194
IN - India 166
MX - Messico 143
ID - Indonesia 138
NL - Olanda 107
BE - Belgio 103
AR - Argentina 91
ZA - Sudafrica 70
ES - Italia 61
IQ - Iraq 60
LT - Lituania 47
PK - Pakistan 46
AT - Austria 43
CZ - Repubblica Ceca 41
VE - Venezuela 37
EC - Ecuador 36
SA - Arabia Saudita 34
CO - Colombia 30
MA - Marocco 25
MY - Malesia 25
CL - Cile 23
UZ - Uzbekistan 22
TN - Tunisia 21
IE - Irlanda 20
PH - Filippine 20
IR - Iran 17
NO - Norvegia 15
NP - Nepal 15
PE - Perù 15
JO - Giordania 14
KE - Kenya 14
KR - Corea 14
AU - Australia 13
BG - Bulgaria 13
DZ - Algeria 13
EG - Egitto 13
PY - Paraguay 13
TW - Taiwan 12
AE - Emirati Arabi Uniti 10
KZ - Kazakistan 10
CR - Costa Rica 9
DO - Repubblica Dominicana 9
JM - Giamaica 9
CH - Svizzera 8
RO - Romania 8
UY - Uruguay 8
BO - Bolivia 7
IL - Israele 7
SY - Repubblica araba siriana 7
TT - Trinidad e Tobago 7
AL - Albania 6
GR - Grecia 6
HN - Honduras 6
LV - Lettonia 6
NG - Nigeria 6
PT - Portogallo 6
DK - Danimarca 5
KW - Kuwait 5
LB - Libano 5
SN - Senegal 5
XK - ???statistics.table.value.countryCode.XK??? 5
ET - Etiopia 4
EU - Europa 4
HU - Ungheria 4
KG - Kirghizistan 4
MD - Moldavia 4
OM - Oman 4
PA - Panama 4
RS - Serbia 4
TH - Thailandia 4
AM - Armenia 3
BH - Bahrain 3
GT - Guatemala 3
LY - Libia 3
MU - Mauritius 3
NI - Nicaragua 3
SI - Slovenia 3
AO - Angola 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
BY - Bielorussia 2
Totale 37.112
Città #
Helsinki 3.979
Singapore 2.057
Ashburn 2.033
Dallas 1.750
Fairfield 1.351
Woodbridge 1.220
San Jose 1.098
Ann Arbor 801
Houston 799
Beijing 761
Hong Kong 687
Santa Clara 676
Chandler 672
Seattle 590
Jacksonville 562
Munich 528
Wilmington 524
Ferrara 487
Cambridge 468
New York 308
Warsaw 308
Ho Chi Minh City 292
Los Angeles 284
Hanoi 229
Tokyo 201
Izmir 200
Council Bluffs 179
Nanjing 176
Princeton 154
Milan 152
Lauterbourg 151
Shanghai 135
Boardman 119
Dong Ket 106
San Diego 103
Jakarta 101
Brussels 97
São Paulo 95
London 94
Orem 94
Mexico City 93
The Dalles 93
Bologna 83
Turku 78
Buffalo 74
Toronto 72
Montreal 66
Frankfurt am Main 62
Da Nang 61
Atlanta 60
Dearborn 60
Hefei 58
Shenyang 57
Chicago 55
Brooklyn 53
Nanchang 51
Amsterdam 50
Poplar 50
Rome 48
Denver 47
Johannesburg 47
Moscow 47
Stockholm 47
Addison 46
Tianjin 46
Rio de Janeiro 45
Bremen 44
Chennai 44
Manchester 40
Phoenix 37
San Francisco 37
Falls Church 36
Haiphong 35
Redwood City 35
Boston 33
Jiaxing 33
Hebei 32
Auburn Hills 31
Falkenstein 31
Porto Alegre 29
Washington 29
Mcallen 26
Norwalk 26
Changsha 25
Mountain View 25
San Mateo 24
Belo Horizonte 22
Curitiba 22
Philadelphia 22
Charlotte 21
Columbus 20
Guangzhou 20
Lahore 20
Montréal 20
New Delhi 20
Ankara 19
Brno 19
Dublin 19
Hải Dương 19
Nuremberg 19
Totale 27.104
Nome #
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 2.941
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.863
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 415
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice 410
A linear allergic contact dermatitis to p-tert-butylphenol formaldehyde resin sectorially present in a neoprene orthopedic brace: role of spectroscopy 339
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles 337
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 334
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 324
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8 ,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vivo studies 318
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence 304
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl 296
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 294
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains 294
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 290
Design and synthesis of99mTcN-labeled dextran-mannose derivatives for sentinel lymph node detection 289
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 284
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice 273
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 272
C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors 259
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 256
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 248
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 246
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 245
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 244
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 242
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor 241
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 240
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4′-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide 239
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 235
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 233
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 230
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 229
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 226
Sviluppo di un Sistema combinato a filiera controllata per l’allevamento, l’estrazione, la caratterizzazione e la sanificazione del secreto di chiocciola 225
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT 225
A new synthetic approach to 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-benzimidazol-2-one (J-113397), the first non-peptide ORL-1 receptor antagonist 224
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 224
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 224
Helix aspersa muller mucus (Helixcomplex ®) interferes with Herpes simplex 1 virus infection 221
Physicochemical stability of cabazitaxel and docetaxel solutions 220
Design of Nanosystems for the Delivery of Quorum Sensing Inhibitors: A Preliminary Study 220
Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic G i/o protein linked pathways 218
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 218
HelixComplex snail mucus as a potential technology against O3 induced skin damage 218
Synthesis and proteasome inhibition of N-allyl vinyl ester-based peptides 217
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: Pharmacological and genetic evidences 216
Synthesis and activity of isoxazoline vinyl ester pseudopeptides as proteasome inhibitors 216
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors 216
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity 215
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24 215
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice 215
JWH-018 impairs sensorimotor functions in mice 214
Letter to the Editor: Antimicrobial properties of mucus from the brown garden snail Helix aspersa 214
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl] methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vitro studies 214
null 214
Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test 213
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 213
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 212
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 210
Further studies at neuropeptide S position 5: Discovery of novel neuropeptide S receptor antagonists 208
Chemoenzymatic Stereodivergent Synthesis of All the Possible Stereoisomers of the 2,3-Dimethylglyceric Acid Ethyl Ester 208
Neuropeptide S receptor ligands: a patent review (2005-2016) 207
Mastering chiral substituted 2-oxopiperazines 206
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 205
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 202
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids 201
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists 199
Structure-activity study at positions 3 and 4 of human neuropeptide S. 195
A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity 194
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway 192
Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice 191
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 190
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity 190
A Cationic Contrast Agent in X-ray Imaging of Articular Cartilage: Pre-Clinical Evaluation of Diffusion and Attenuation Properties 187
Enzymatic esterification as potential strategy to enhance the sorbic acid behavior as food and beverage preservative 187
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting thefolate pathway 186
Recent advances in the stereoselective synthesis of trans-3,4- disubstituted-piperidines: applications to (-)paroxetine 185
Glyceric Prodrug of Ursodeoxycholic Acid (UDCA): Novozym 435-Catalyzed Synthesis of UDCA-Monoglyceride 185
Synthetic cannabinoid JWH-018 impairs object recognition memory in mice: behavioral and electrophysiological evidence 185
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors 184
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5 183
Designing a new bioconjugate FA-LR and studies of the effects in human ovarian cancer cell lines 182
A Convenient Route to Enantiomerically Pure 2-Substituted Methyl Glycerate Derivatives 182
NOP receptor pharmacological profile – A dynamic mass redistribution study 182
Anxiolytic and antidepressant-like activities of UFP-512, a novel selective delta opiold receptor agonist 181
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 180
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 179
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 179
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor 178
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist 177
Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine-lactone induces HLA-G expression in human immune cells 176
6-N,N-dimethylamino-2,3-naphthalimide: A new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides 175
A proteomic approach to investigate the mechanism of action of anticancer peptides 175
Xylitol as a Hydrophilization Moiety for a Biocatalytically Synthesized Ibuprofen Prodrug 175
Synthesis of 2,6-Dimethyltyrosine-Like Amino Acids through Pinacolinamide-Enabled C-H Dimethylation of 4-Dibenzylamino Phenylalanine 175
DAG-MAG-BHB: A Novel Ketone Diester Modulates NLRP3 Inflammasome Activation in Microglial Cells in Response to Beta-Amyloid and Low Glucose AD-like Conditions 174
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 173
Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors 173
An alternative enzymatic route to the ergogenic ketone body ester (R)-3-hydroxybutyl (r)-3-hydroxybutyrate 173
Helix aspersa muller mucus (Helixcomplex ®) p41 protein prevents Pseudomonas aeruginosa growth and promotes mammalian bronchial epithelial cell proliferation 171
Totale 27.771
Categoria #
all - tutte 144.538
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 671
Totale 145.209


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021240 0 0 0 0 0 0 0 0 0 0 0 240
2021/20221.780 107 169 150 104 138 68 123 99 75 134 165 448
2022/20231.779 180 156 70 207 254 202 110 158 227 18 111 86
2023/20241.279 90 121 90 37 92 227 74 109 38 49 44 308
2024/20254.834 112 123 405 256 487 459 281 306 861 388 632 524
2025/202618.153 1.427 835 2.202 1.576 1.824 869 1.583 745 4.802 1.394 631 265
Totale 37.531