TRAPELLA, Claudio
 Distribuzione geografica
Continente #
NA - Nord America 18.076
EU - Europa 9.524
AS - Asia 8.656
SA - Sud America 1.223
Continente sconosciuto - Info sul continente non disponibili 386
AF - Africa 196
OC - Oceania 17
Totale 38.078
Nazione #
US - Stati Uniti d'America 17.588
FI - Finlandia 4.191
SG - Singapore 3.244
CN - Cina 2.138
IT - Italia 1.553
DE - Germania 1.058
VN - Vietnam 1.040
BR - Brasile 957
HK - Hong Kong 719
GB - Regno Unito 599
UA - Ucraina 525
TR - Turchia 381
PL - Polonia 323
FR - Francia 283
SE - Svezia 270
CA - Canada 268
BD - Bangladesh 240
JP - Giappone 235
RU - Federazione Russa 194
IN - India 166
MX - Messico 143
ID - Indonesia 138
NL - Olanda 109
BE - Belgio 103
AR - Argentina 91
ZA - Sudafrica 70
ES - Italia 62
IQ - Iraq 60
LT - Lituania 47
PK - Pakistan 46
AT - Austria 43
CZ - Repubblica Ceca 41
EC - Ecuador 38
VE - Venezuela 37
SA - Arabia Saudita 34
CO - Colombia 31
MY - Malesia 26
MA - Marocco 25
CL - Cile 23
UZ - Uzbekistan 22
TN - Tunisia 21
IE - Irlanda 20
PH - Filippine 20
IR - Iran 17
JM - Giamaica 16
PE - Perù 16
KR - Corea 15
NO - Norvegia 15
NP - Nepal 15
AU - Australia 14
JO - Giordania 14
KE - Kenya 14
BG - Bulgaria 13
DZ - Algeria 13
EG - Egitto 13
PY - Paraguay 13
CR - Costa Rica 12
TW - Taiwan 12
AE - Emirati Arabi Uniti 10
KZ - Kazakistan 10
DO - Repubblica Dominicana 9
CH - Svizzera 8
HN - Honduras 8
NG - Nigeria 8
RO - Romania 8
UY - Uruguay 8
BO - Bolivia 7
IL - Israele 7
SY - Repubblica araba siriana 7
TT - Trinidad e Tobago 7
AL - Albania 6
GR - Grecia 6
LV - Lettonia 6
PT - Portogallo 6
DK - Danimarca 5
GT - Guatemala 5
KW - Kuwait 5
LB - Libano 5
SN - Senegal 5
TH - Thailandia 5
XK - ???statistics.table.value.countryCode.XK??? 5
ET - Etiopia 4
EU - Europa 4
HU - Ungheria 4
KG - Kirghizistan 4
MD - Moldavia 4
NI - Nicaragua 4
OM - Oman 4
PA - Panama 4
RS - Serbia 4
SV - El Salvador 4
AM - Armenia 3
BH - Bahrain 3
LY - Libia 3
MU - Mauritius 3
SI - Slovenia 3
AO - Angola 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
Totale 37.653
Città #
Helsinki 3.979
Ashburn 2.070
Singapore 2.070
Dallas 1.756
Fairfield 1.351
Woodbridge 1.220
San Jose 1.124
Houston 803
Ann Arbor 801
Beijing 777
Santa Clara 693
Hong Kong 692
Chandler 672
Seattle 591
Jacksonville 562
Munich 528
Wilmington 524
Ferrara 498
Cambridge 469
New York 310
Warsaw 308
Ho Chi Minh City 292
Los Angeles 292
Council Bluffs 260
Hanoi 229
Tokyo 201
Izmir 200
Nanjing 176
Milan 163
Princeton 154
Lauterbourg 151
Shanghai 137
Boardman 119
Dong Ket 106
San Diego 103
Jakarta 101
Brussels 97
London 96
São Paulo 95
Orem 94
The Dalles 94
Mexico City 93
Toronto 89
Bologna 84
Turku 78
Buffalo 75
Montreal 67
Atlanta 63
Frankfurt am Main 62
Da Nang 61
Dearborn 60
Chicago 58
Hefei 58
Shenyang 57
Rome 55
Brooklyn 54
Moscow 53
Nanchang 51
Amsterdam 50
Poplar 50
Denver 47
Johannesburg 47
Stockholm 47
Addison 46
Tianjin 46
Rio de Janeiro 45
Bremen 44
Chennai 44
Phoenix 44
Manchester 40
San Francisco 39
Falls Church 36
Haiphong 35
Redwood City 35
Boston 33
Jiaxing 33
Hebei 32
Auburn Hills 31
Falkenstein 31
Washington 30
Porto Alegre 29
Mcallen 26
Norwalk 26
Changsha 25
Mountain View 25
Philadelphia 25
San Mateo 24
Belo Horizonte 23
Curitiba 22
Charlotte 21
Columbus 21
Guangzhou 20
Lahore 20
Montréal 20
New Delhi 20
Ankara 19
Brno 19
Dublin 19
Hải Dương 19
Nuremberg 19
Totale 27.403
Nome #
1,3,8-Triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury. 2.948
1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects 2.867
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies 421
1‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice 414
1,4-Dithiane-2,5-diol: An Attractive Platform for the Synthesis of Sulfur-Containing Functionalized Heterocycles 343
A linear allergic contact dermatitis to p-tert-butylphenol formaldehyde resin sectorially present in a neoprene orthopedic brace: role of spectroscopy 339
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 337
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 333
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8 ,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vivo studies 321
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence 310
In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl 306
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 298
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains 298
A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ 291
Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice 289
Design and synthesis of99mTcN-labeled dextran-mannose derivatives for sentinel lymph node detection 289
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice 277
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 274
C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors 263
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting 260
[D-Pen(p-tBuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies 253
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 251
Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors 248
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4′-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide 245
N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands 244
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 244
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 243
Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor 241
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist 238
C subunit of F1/FO-ATP synthase as target for preventing the detrimental effect of myocardial ischemia/reperfusion injury 237
Tryptophan replacement in the nociceptin/orphanin FQ receptor ligand Ac-RYYRWK-NH2 233
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT 231
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 231
Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120 229
Sviluppo di un Sistema combinato a filiera controllata per l’allevamento, l’estrazione, la caratterizzazione e la sanificazione del secreto di chiocciola 228
A new synthetic approach to 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-benzimidazol-2-one (J-113397), the first non-peptide ORL-1 receptor antagonist 227
Physicochemical stability of cabazitaxel and docetaxel solutions 227
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 225
Design of Nanosystems for the Delivery of Quorum Sensing Inhibitors: A Preliminary Study 225
Conformation-activity relationship of neuropeptide S and some structural mutants: Helicity affects their interaction with the receptor 225
Helix aspersa muller mucus (Helixcomplex ®) interferes with Herpes simplex 1 virus infection 224
Anxiolytic- and antidepressant-like activities of H-Dmt-Tic-NH-CH(CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist 222
Neuropeptide S receptor ligands: a patent review (2005-2016) 222
HelixComplex snail mucus as a potential technology against O3 induced skin damage 222
Synthesis and activity of isoxazoline vinyl ester pseudopeptides as proteasome inhibitors 221
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24 220
Letter to the Editor: Antimicrobial properties of mucus from the brown garden snail Helix aspersa 220
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: Pharmacological and genetic evidences 219
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice 219
Synthesis and proteasome inhibition of N-allyl vinyl ester-based peptides 219
Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic G i/o protein linked pathways 218
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity 218
JWH-018 impairs sensorimotor functions in mice 217
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors 216
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl] methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vitro studies 216
null 214
N-carbamidoyl-4-((3-ethyl-2,4,4-trimethylcyclohexyl)methyl)benzamide enhances staurosporine cytotoxic effects likely inhibiting the protective action of Magmas toward cell apoptosis 214
In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403 214
Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test 213
Synthesis and biological activity of human neuropeptide S analogues modified in position 2 212
Further studies at neuropeptide S position 5: Discovery of novel neuropeptide S receptor antagonists 208
Chemoenzymatic Stereodivergent Synthesis of All the Possible Stereoisomers of the 2,3-Dimethylglyceric Acid Ethyl Ester 208
Mastering chiral substituted 2-oxopiperazines 207
Pharmacological profile of nociceptin/orphanin FQ receptors interacting with G-proteins and β-arrestins 2 205
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. 204
Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with C alpha,alpha-dialkylated amino acids 203
Synthesis and Biological Activity of Human Neuropeptide S Analogues Modified in Position 5: Identification of Potent and Pure Neuropeptide S Receptor Antagonists 202
A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity 198
Structure-activity study at positions 3 and 4 of human neuropeptide S. 196
Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68). 193
Novel halogenated synthetic cannabinoids impair sensorimotor functions in mice 193
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway 192
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting thefolate pathway 191
Intrathecal administration of nociceptin/orphanin FQ receptor agonists in rats: A strategy to relieve chemotherapy-induced neuropathic hypersensitivity 190
Enzymatic esterification as potential strategy to enhance the sorbic acid behavior as food and beverage preservative 190
Designing a new bioconjugate FA-LR and studies of the effects in human ovarian cancer cell lines 189
Recent advances in the stereoselective synthesis of trans-3,4- disubstituted-piperidines: applications to (-)paroxetine 189
A Cationic Contrast Agent in X-ray Imaging of Articular Cartilage: Pre-Clinical Evaluation of Diffusion and Attenuation Properties 187
DAG-MAG-BHB: A Novel Ketone Diester Modulates NLRP3 Inflammasome Activation in Microglial Cells in Response to Beta-Amyloid and Low Glucose AD-like Conditions 187
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors 187
Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5 187
Glyceric Prodrug of Ursodeoxycholic Acid (UDCA): Novozym 435-Catalyzed Synthesis of UDCA-Monoglyceride 187
Synthetic cannabinoid JWH-018 impairs object recognition memory in mice: behavioral and electrophysiological evidence 187
A Convenient Route to Enantiomerically Pure 2-Substituted Methyl Glycerate Derivatives 183
NOP receptor pharmacological profile – A dynamic mass redistribution study 183
In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1 182
Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist 181
Anxiolytic and antidepressant-like activities of UFP-512, a novel selective delta opiold receptor agonist 181
Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands 180
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11) 180
NOP agonist action of cebranopadol counteracts its liability to promote physical dependence 179
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor 179
An alternative enzymatic route to the ergogenic ketone body ester (R)-3-hydroxybutyl (r)-3-hydroxybutyrate 178
Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine-lactone induces HLA-G expression in human immune cells 177
6-N,N-dimethylamino-2,3-naphthalimide: A new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides 176
A proteomic approach to investigate the mechanism of action of anticancer peptides 176
Synthesis of 2,6-Dimethyltyrosine-Like Amino Acids through Pinacolinamide-Enabled C-H Dimethylation of 4-Dibenzylamino Phenylalanine 176
Microwave-assisted enzymatic synthesis of geraniol esters in solvent-free systems: optimization of the reaction parameters, purification and characterization of the products, and biocatalyst reuse 175
New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores 175
Novel Mixed NOP/Opioid Receptor Peptide Agonists 175
Totale 28.079
Categoria #
all - tutte 149.362
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 691
Totale 150.053


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.673 0 169 150 104 138 68 123 99 75 134 165 448
2022/20231.779 180 156 70 207 254 202 110 158 227 18 111 86
2023/20241.279 90 121 90 37 92 227 74 109 38 49 44 308
2024/20254.834 112 123 405 256 487 459 281 306 861 388 632 524
2025/202618.166 1.427 835 2.202 1.576 1.824 869 1.583 745 4.802 1.394 631 278
2026/2027534 410 124 0 0 0 0 0 0 0 0 0 0
Totale 38.078