MORARI, Michele
 Distribuzione geografica
Continente #
NA - Nord America 14.619
AS - Asia 7.243
EU - Europa 4.009
SA - Sud America 993
AF - Africa 152
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 4
Totale 27.035
Nazione #
US - Stati Uniti d'America 14.294
SG - Singapore 2.689
CN - Cina 1.816
VN - Vietnam 861
DE - Germania 794
BR - Brasile 760
UA - Ucraina 638
IT - Italia 631
HK - Hong Kong 511
GB - Regno Unito 466
TR - Turchia 434
FI - Finlandia 415
FR - Francia 261
BD - Bangladesh 221
JP - Giappone 183
SE - Svezia 181
CA - Canada 166
RU - Federazione Russa 159
IN - India 145
MX - Messico 123
PL - Polonia 119
ID - Indonesia 105
AR - Argentina 89
AT - Austria 72
ZA - Sudafrica 61
ES - Italia 55
NL - Olanda 53
BE - Belgio 52
PK - Pakistan 50
IQ - Iraq 47
EC - Ecuador 34
CO - Colombia 30
VE - Venezuela 29
LT - Lituania 28
PH - Filippine 22
MA - Marocco 21
UZ - Uzbekistan 19
SA - Arabia Saudita 18
EG - Egitto 17
MY - Malesia 17
PE - Perù 16
KE - Kenya 15
AE - Emirati Arabi Uniti 13
AU - Australia 13
CL - Cile 13
CZ - Repubblica Ceca 13
JO - Giordania 13
IR - Iran 11
CH - Svizzera 9
NO - Norvegia 9
BG - Bulgaria 8
BO - Bolivia 8
ET - Etiopia 8
IE - Irlanda 8
NP - Nepal 8
PY - Paraguay 8
TN - Tunisia 8
AZ - Azerbaigian 7
CR - Costa Rica 7
DZ - Algeria 7
IL - Israele 7
PA - Panama 7
KG - Kirghizistan 6
KZ - Kazakistan 6
HN - Honduras 5
PS - Palestinian Territory 5
RO - Romania 5
AL - Albania 4
BH - Bahrain 4
JM - Giamaica 4
LV - Lettonia 4
PT - Portogallo 4
TT - Trinidad e Tobago 4
UY - Uruguay 4
BW - Botswana 3
DK - Danimarca 3
HR - Croazia 3
KR - Corea 3
LY - Libia 3
OM - Oman 3
RS - Serbia 3
CG - Congo 2
DM - Dominica 2
DO - Repubblica Dominicana 2
EE - Estonia 2
EU - Europa 2
GE - Georgia 2
GR - Grecia 2
KH - Cambogia 2
LK - Sri Lanka 2
MT - Malta 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
QA - Qatar 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
SR - Suriname 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
TW - Taiwan 2
Totale 27.016
Città #
Ashburn 1.873
Singapore 1.754
Fairfield 1.266
Woodbridge 1.234
San Jose 1.105
Houston 704
Jacksonville 674
Beijing 671
Chandler 666
Santa Clara 602
Ann Arbor 517
Hong Kong 501
Seattle 487
Wilmington 450
Cambridge 416
Munich 365
Dallas 283
Ho Chi Minh City 259
Izmir 239
New York 216
Los Angeles 212
Helsinki 211
Hanoi 204
Tokyo 175
Nanjing 173
Ferrara 171
Princeton 166
Council Bluffs 163
Lauterbourg 131
San Diego 114
Warsaw 109
Shanghai 106
Boardman 105
Milan 96
São Paulo 78
Jakarta 76
London 71
Mexico City 69
Bremen 66
Orem 64
Turku 58
Buffalo 57
Shenyang 57
Brussels 50
Tianjin 50
Brooklyn 49
Chicago 49
Da Nang 49
Falls Church 48
Montreal 48
The Dalles 48
Atlanta 45
Hebei 45
Hefei 45
Toronto 45
Vienna 45
Moscow 44
Frankfurt am Main 43
Denver 42
Boston 39
Nanchang 38
Haiphong 35
Chennai 34
Stockholm 34
Johannesburg 33
Changsha 31
Manchester 31
Norwalk 30
Jiaxing 29
Phoenix 29
Poplar 29
San Francisco 27
Washington 27
Biên Hòa 26
Rio de Janeiro 25
San Mateo 25
Ankara 24
Auburn Hills 24
Rome 24
Amsterdam 22
Jinan 22
Falkenstein 21
Mountain View 21
New Delhi 20
Ottawa 20
Redwood City 20
Guangzhou 19
Baghdad 18
Belo Horizonte 18
Brasília 18
Charlotte 18
Mumbai 18
Dearborn 17
Tashkent 17
Zhengzhou 17
Istanbul 16
Nuremberg 16
Querétaro 16
Lahore 15
Lappeenranta 14
Totale 18.736
Nome #
[Nphe(1),Arg(14),Lys(15)]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor 394
Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111 376
Eltoprazine prevents levodopa-induced dyskinesias by reducing striatal glutamate and direct pathway activity 329
Anti-Parkinsonian and anti-dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists 308
Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease 277
D-Aspartate oxidase influences glutamatergic system homeostasis in mammalian brain 274
Safinamide differentially modulates in vivo glutamate and GABA release in the rat hippocampus and basal ganglia 272
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor 272
Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice 270
In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to L-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels 267
GluN2A and GluN2B NMDA receptor subunits differentially modulate striatal output pathways and contribute to levodopa-induced abnormal involuntary movements in dyskinetic rats 263
Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior 259
G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice 257
Amantadine attenuates levodopa-induced dyskinesia in mice and rats preventing the accompanying rise in nigral GABA levels 240
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices 237
5‐Hydroxytryptamine‐mediated effects of nicotine on endogenous GABA efflux from guinea‐pig cortical slices 236
Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia 235
Antagonisti dei recettori NOP e loro usi terapeutici 230
Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease 229
Antagonism of metabotropic glutamate receptor type 5 attenuates L-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease 228
Loss of cortical GABA terminals in Unverricht–Lundborg disease 227
Changes of glutamatergic control of striatal acetylcholine release in experimental parkinsonism 225
Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex 224
Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging 223
Protein Kinase C β: a New Target Therapy to Prevent the Long-Term Atypical Antipsychotic-Induced Weight Gain 222
Striatal Dopamine-NMDA receptor interactions in the modulation of glutamate release in the substantia nigra pars reticulata in vivo: opposite role for D1 and D2 receptors 221
Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic G i/o protein linked pathways 218
Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release 218
Autophagy and LRRK2 in the Aging Brain 217
Dopamine-nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity 215
Genetic deletion of Rhes or pharmacological blockade of mTORC1 prevent striato-nigral neurons activation in levodopa-induced dyskinesia 215
Role of LRRK2 in the regulation of dopamine receptor trafficking 215
Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes 215
Alpha-2 adrenoreceptor-mediated decrease in gamma-aminobutyric acid outflow in cortical slices and synaptosomes during morphine tolerance 214
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl] methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In vitro studies 214
Differential responsiveness of rat striatal nerve endings to the mitochondrial toxin 3-nitropropionic acid: implications for Huntington’s disease 214
Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]‐d‐aspartate and endogenous GABA in freely moving guinea‐pigs 213
Loss of the preferential control over the striato-nigral direct pathway by striatal NMDA receptors in a rat model of Parkinson's disease 212
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease 208
Differential effect of NR2A and NR2B subunit selective NMDA receptor antagonists on striato-pallidal neurons: relationship to motor response in the 6-hydroxydopamine model of parkinsonism 205
NR2B subunit blockade does not affect motor symptoms induced by 3-nitropropionic acid 205
NOP receptor ligands and Parkinson’s disease 203
Striatal glutamate release evoked in vivo by NMDA is dependent upon ongoing neuronal activity in the substantia nigra, endogenous striatal substance P and dopamine 202
Plasticity of glutamatergic control of striatal acetylcholine release in experimental parkinsonism: opposite changes at group-II metabotropic and NMDA receptors 202
Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex 201
Nanoparticulate lipid dispersions for bromocriptine delivery: characterization and in vivo study 201
Selectivity and Anti-Parkinsons Potential of Thiadiazolidinone RGS4 Inhibitors 201
Blockade of nociceptin/orphanin FQ transmission in rat substantia nigra reverses haloperidol-induced akinesia and normalizes nigral glutamate release 201
Pharmacological and genetic evidence for pre- and postsynaptic D2 receptor involvement in motor responses to nociceptin/orphanin FQ receptor ligands 200
Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance 200
Lipid nanocarriers containing a Levodopa prodrug with potential antiparkinsonian activity 196
Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity 195
Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat - I. Effects of perfusion with tetrodotoxin and low-calcium medium 194
Progressive Motor Cortex Functional Reorganization Following 6-Hydroxydopamine Lesioning in Rats 194
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway 192
Nociceptin/Orphanin FQ Inhibits the Survival and Axon Growth of Midbrain Dopaminergic Neurons Through a p38-MAPK Dependent Mechanism 191
NMDA and non-NMDA ionotropic glutamate receptors modulate striatal acetylcholine release via pre- and postsynaptic mechanisms 190
Increased responsivity of glutamate release from the substantia nigra pars reticulata to striatal NMDA receptor blockade in a model of Parkinson's disease. A dual probe microdialysis study in hemiparkinsonian rats 189
Stimulation of Delta Opioid Receptor and Blockade of Nociceptin/Orphanin FQ Receptor Synergistically Attenuate Parkinsonism 188
Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4 188
Agonisti dei recettori NOP per il trattamento delle discinesie da levodopa; 187
Direct and indirect inhibition by nociceptin/orphanin FQ on noradrenaline release from rodent cerebral cortex in vitro 185
Nociceptin/Orphanin FQ Receptor Agonists Attenuate L-DOPA-Induced Dyskinesias 184
Differential role of striatal and nigral D1receptors in the expression of L-DOPA induced dyskinesia and its neurochemical correlates 184
Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease 182
Nanostructured lipid carriers as delivery systems for parkinson’s therapy 181
Glutamate antagonists prevent morphine withdrawal in mice and guinea pigs 180
Parkinson's disease: no NOP, new hope 176
Evidence for a striatal NMDA receptor modulation of nigral glutamate release. A dual probe microdialysis study in the awake freely moving rat 174
Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease 171
Effect of (-)nicotine on GABA efflux from guinea pig cerebral cortex slices. 170
Managing Parkinson's disease: moving ON with NOP 170
Excitatory amino acids (EAAs) stimulate phosphatidylinositol turnover in adult rat striatal slices: interaction between NMDA and EAA metabotropic receptors. 168
Presynaptic group I and II metabotropic glutamate receptors oppositely modulate striatal acetylcholine release 165
Novel therapeutic strategies for treatment of motor abnormalities in Parkinson’s disease: focus on opioid receptors 165
Nociceptin/orphanin FQ receptors modulate glutamate extracellular levels in the substantia nigra pars reticulata. A microdialysis study in the awake freely moving rat 162
Inhibitory effect of NMDA receptor activation on quisqualate-stimulated phosphatidylinositol turnover in the human cerebral cortex 161
L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum 161
Discovery and Structure-Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson's Disease Models 160
In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity 160
6-Hydroxydopamine lesion and levodopa treatment modify the effect of buspirone in the substantia nigra pars reticulata 160
Dopamine D2 receptor activation potently inhibits striatal glutamatergic transmission in a G2019S LRRK2 genetic model of Parkinson's disease 159
Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling 159
L-DOPA promotes striatal dopamine release through D1 receptors and reversal of dopamine transporter 158
Nociceptin/orphanin FQ receptor antagonists riverse akinesia in rat parkinsonian models 156
L-DOPA-induced modulation of GABA and glutamate release in the substantia nigra pars reticulata and globus pallidus in a rat model of dyskinesia 156
Nociceptin/orphanin FQ receptors modulate locomotion and motor cortex excitability in adult Rats 156
Evidence for a protective action of the vigilance promoting drug modafinil on the MPTP-induced degeneration of the nigrostriatal dopamine neurons in the black mouse: an immunocytochemical and biochemical analysis 155
Nociceptin/orphanin FQ receptor antagonists reverse parkinsonism in MPTP-treated mice and non-human primates 152
Physiopathological aspects of NMDA transmission in the basal ganglia. In vitro and in vivo release studies 151
Molecular and imaging prodromal markers of dopamine neuron degeneration in animal models of Parkinson’s disease: pathophysiology and clinical perspectives 151
Dopamine Transporter, PhosphoSerine129 α-Synuclein and α-Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice 151
Striatal and nigral muscarinic type 1 and type 4 receptors modulate levodopa-induced dyskinesia and striato-nigral pathway activation in 6-hydroxydopamine hemilesioned rats 149
Nociceptin/orphanin FQ and neurotransmitter release in the central nervous system 147
Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson’s disease 146
Safinamide inhibits in vivo glutamate release in a rat model of Parkinson's disease 146
L-glutamate and gamma-aminobutyric acid efflux from rat cerebrocortical synaptosomes: Modulation by kappa- and mu- but not delta- and opioid receptor like-1 receptors 144
Safinamide Modulates Striatal Glutamatergic Signaling in a Rat Model of Levodopa-Induced Dyskinesia 143
Synthesis and structure activity relationships of delthorphine analogues 142
Modulation of 5-hydroxytryptamine efflux from rat cortical synaptosomes by opioids and nociceptin 142
Totale 20.190
Categoria #
all - tutte 119.508
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 2.494
Totale 122.002


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021139 0 0 0 0 0 0 0 0 0 0 0 139
2021/20221.562 53 169 130 70 81 95 98 87 55 117 153 454
2022/20231.619 170 132 75 181 263 218 72 124 224 4 101 55
2023/2024803 84 103 39 23 76 135 34 63 24 19 9 194
2024/20253.708 74 88 310 82 402 505 146 204 569 373 528 427
2025/202611.001 1.178 343 893 1.354 1.681 739 1.415 556 979 1.198 465 200
Totale 27.253