Letter (provided by the authors): The association between diabetes mellitus (DM) and TTC has been matter of several investigations. Pelliccia et al, evaluating a series of 19 studies (1,109 patients), concluded that patients with TTC have a relevant prevalence of cardiovascular risk factors and associated comorbidities. Obesity was present in 17% of patients, hypertension in 54%, smoking in 22%, dyslipidemia in 32%, and DM in 17% . A recent review of papers accessed in PubMed to evaluate the prevalence of DM in TTC patients (959 studies, 33,894 patients), confirmed an overall prevalence of 16.8%. A gender difference for mortality has been confirmed also very recently. An analysis of all patients ≥18 years of age diagnosed with TTC identified in the Nationwide Inpatient Sample (NIS) 2009-2010 database, found that the total in-hospital mortality rate was 2.4%, with a higher mortality in men (4.8%) than in women (2.1%). Sepsis (9 vs. 4.2%) was more prevalent in men with an increased prevalence of other critical illness. Further studies are needed on this relatively infrequent, but potentially harmful relationship.
Possible association between Takotsubo cardiomyopathy, sepsis, and diabetes mellitus: a still open question.
FABBIAN, Fabio;TISEO, Ruana;SIGNANI, Fulvia;ZUCCHI, Beatrice;MANFREDINI, Roberto
2015
Abstract
Letter (provided by the authors): The association between diabetes mellitus (DM) and TTC has been matter of several investigations. Pelliccia et al, evaluating a series of 19 studies (1,109 patients), concluded that patients with TTC have a relevant prevalence of cardiovascular risk factors and associated comorbidities. Obesity was present in 17% of patients, hypertension in 54%, smoking in 22%, dyslipidemia in 32%, and DM in 17% . A recent review of papers accessed in PubMed to evaluate the prevalence of DM in TTC patients (959 studies, 33,894 patients), confirmed an overall prevalence of 16.8%. A gender difference for mortality has been confirmed also very recently. An analysis of all patients ≥18 years of age diagnosed with TTC identified in the Nationwide Inpatient Sample (NIS) 2009-2010 database, found that the total in-hospital mortality rate was 2.4%, with a higher mortality in men (4.8%) than in women (2.1%). Sepsis (9 vs. 4.2%) was more prevalent in men with an increased prevalence of other critical illness. Further studies are needed on this relatively infrequent, but potentially harmful relationship.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
