PACIFICO, Salvatore
 Distribuzione geografica
Continente #
NA - Nord America 3.152
EU - Europa 940
AS - Asia 430
SA - Sud America 9
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 4.537
Nazione #
US - Stati Uniti d'America 3.148
IT - Italia 330
PL - Polonia 246
CN - Cina 219
UA - Ucraina 89
TR - Turchia 86
SG - Singapore 69
DE - Germania 60
GB - Regno Unito 58
SE - Svezia 43
IE - Irlanda 40
ID - Indonesia 23
FI - Finlandia 22
BE - Belgio 17
VN - Vietnam 15
CZ - Repubblica Ceca 14
BR - Brasile 5
FR - Francia 5
IN - India 5
RU - Federazione Russa 4
CA - Canada 3
EU - Europa 3
HK - Hong Kong 3
IR - Iran 3
AR - Argentina 2
AT - Austria 2
AU - Australia 2
CL - Cile 2
JP - Giappone 2
RO - Romania 2
BG - Bulgaria 1
BS - Bahamas 1
CH - Svizzera 1
DK - Danimarca 1
ES - Italia 1
GR - Grecia 1
IL - Israele 1
KR - Corea 1
KW - Kuwait 1
MK - Macedonia 1
MY - Malesia 1
NL - Olanda 1
NZ - Nuova Zelanda 1
PK - Pakistan 1
PT - Portogallo 1
Totale 4.537
Città #
Fairfield 480
Woodbridge 374
Ashburn 259
Warsaw 246
Ann Arbor 241
Houston 218
Chandler 212
Seattle 188
Ferrara 184
Cambridge 177
Wilmington 154
Jacksonville 119
Menlo Park 98
Beijing 56
New York 55
Princeton 55
Shanghai 47
Izmir 44
Nanjing 41
Singapore 37
Milan 32
San Diego 28
Addison 24
Jakarta 23
Los Angeles 23
Nanchang 20
Boardman 19
Dearborn 18
Brussels 17
Dong Ket 15
Ferrara di Monte Baldo 13
Redwood City 13
St Louis 12
Mountain View 11
Brno 10
Falls Church 10
London 10
Bologna 9
Bremen 9
Norwalk 9
Des Moines 8
Cagliari 7
Jinan 7
San Mateo 7
Shenyang 7
Changsha 6
Padova 6
Washington 6
Hebei 5
Jiaxing 5
Auburn Hills 4
Grassano 4
Guangzhou 4
Olomouc 4
Rome 4
Bari 3
Bournemouth 3
Hefei 3
Helsinki 3
Leawood 3
Munich 3
Ningbo 3
Orange 3
Tappahannock 3
Tianjin 3
Waban 3
Ardabil 2
Aversa 2
Buenos Aires 2
Chicago 2
Dublin 2
Florence 2
Fort Huachuca 2
Haikou 2
Hong Kong 2
Hyderabad 2
Islington 2
Kunming 2
La Canada Flintridge 2
Lanzhou 2
Lugo 2
Minneapolis 2
Modena 2
Montreal 2
Pozzo 2
Prescot 2
Torino 2
Turin 2
Walnut 2
Acton 1
Albert Park 1
Athens 1
Augusta 1
Beirã 1
Bitam 1
Capaccio 1
Castellana Grotte 1
Catania 1
Central District 1
Chiswick 1
Totale 3.784
Nome #
Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer’s disease 222
Sintesi di glicopeptidi mediante le reazioni tiol-ene/ino e studio della reattività di Umpolung di α-dichetoni 188
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 164
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 152
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones 146
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 137
Photoinduced addition of glycosyl thiols to alkynyl peptides: use of free-radical thiol-yne coupling for post-translational double-glycosylation of peptides 135
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 125
Modulation of the NOP receptor signaling affects resilience to acute stress 124
One-pot, two-step desymmetrization of symmetrical benzils catalyzed by the methylsulfinyl (dimsyl) anion 123
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones 122
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 120
Synthesis of S-glycosyl amino acids and S-glycopeptides via photoinduced click thiol-ene coupling 112
null 110
null 108
Neuropeptide S receptor ligands: a patent review (2005-2016) 104
Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology 104
Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor 101
Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation 100
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles 99
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 98
null 94
null 92
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? 91
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 91
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 91
Peptide welding technology – A simple strategy for generating innovative ligands for G protein coupled receptors 86
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 85
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 83
null 79
Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5 79
alpha-Diketones as acyl anion equivalents: a non-enzymatic thiamine-promoted route to aldehyde ketone coupling in PEG(400) as recyclable medium 76
Thiazolium-catalyzed intermolecular Stetter reaction of linear and cyclic alkyl α-diketones 75
The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation 75
Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease 67
alpha-Diketones as acyl anion equivalents: new enzymatic and non-enzymatic thiamine-promoted routes to aldehyde-ketone coupling 64
null 57
Reactivity of dialkyl and diaryl alpha-diketones with N-heterocyclic carbenes 53
Synthesis of folic acid functionalized gold nanoclusters for targeting folate receptor-positive cells 53
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders 43
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 43
Probing the Effect of Sildenafil on Progesterone and Testosterone Production by an Intracellular FRET/BRET Combined Approach 40
Novel Mixed NOP/Opioid Receptor Peptide Agonists 39
Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines 37
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 37
Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects 35
Cyclic peptides acting as allosteric inhibitors of human thymidylate synthase and cancer cell growth 31
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative 26
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists 26
Ageing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2 23
Thermodynamic Stability and Speciation of Ga(III) and Zr(IV) Complexes with High-Denticity Hydroxamate Chelators 23
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 22
Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase 22
Dimethyl Sulfoxide and N,N-dimethylformamide as Umpolung Pre-catalysts in Cross Benzoin Reactions of alpha-Diketones with Aldehydes 21
Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment 20
Unexpected reactivity of diaryl α-diketones with thiazolium carbenes: discovery of a novel multicomponent reaction for the facile synthesis of 1,4-thiazin-3-ones 19
Methylsulfinyl (Dimsyl) Anion as Umpolung Catalyst for the Chemoselective Cross Benzoin Reaction of α-Diketones with Aldehydes 19
Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease 17
Thiazolium-Functionalized Polystyrene Monolithic Microreactors for Continuous-Flow Umpolung Catalysis 14
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells 12
Thiazolium-functionalized polystyrene monolithic microreactors for continuous-flow umpolung catalysis 11
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 10
Phosphodiesterase (PDE) 5 inhibitors sildenafil, tadalafil and vardenafil impact cAMP-specific PDE8 isoforms-linked second messengers and steroid production in a mouse Leydig tumor cell line 10
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 8
Synthesis of Chiral Ionic Liquids from Natural Monosaccharides 5
Totale 4.698
Categoria #
all - tutte 22.384
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.384


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.009 131 39 35 131 72 117 122 101 104 72 50 35
2020/20211.027 47 104 47 74 73 93 92 115 46 178 76 82
2021/2022690 31 91 147 32 27 33 43 26 33 51 34 142
2022/2023522 57 61 12 60 73 53 49 45 55 3 39 15
2023/2024481 50 47 24 25 25 81 25 47 22 24 14 97
2024/202546 46 0 0 0 0 0 0 0 0 0 0 0
Totale 4.698