PACIFICO, Salvatore
 Distribuzione geografica
Continente #
NA - Nord America 3.478
EU - Europa 1.170
AS - Asia 895
SA - Sud America 72
AF - Africa 3
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 5.624
Nazione #
US - Stati Uniti d'America 3.463
SG - Singapore 447
IT - Italia 435
PL - Polonia 247
CN - Cina 245
DE - Germania 96
TR - Turchia 90
UA - Ucraina 89
GB - Regno Unito 70
BR - Brasile 57
ID - Indonesia 57
SE - Svezia 43
IE - Irlanda 42
FI - Finlandia 38
BE - Belgio 24
VN - Vietnam 16
CZ - Repubblica Ceca 14
NL - Olanda 14
CA - Canada 13
RU - Federazione Russa 13
AT - Austria 11
FR - Francia 8
HK - Hong Kong 8
AR - Argentina 6
ES - Italia 5
IN - India 5
LT - Lituania 5
IR - Iran 4
CL - Cile 3
EU - Europa 3
PE - Perù 3
AU - Australia 2
BD - Bangladesh 2
BG - Bulgaria 2
DK - Danimarca 2
JP - Giappone 2
KW - Kuwait 2
KZ - Kazakistan 2
PK - Pakistan 2
PT - Portogallo 2
RO - Romania 2
SA - Arabia Saudita 2
UZ - Uzbekistan 2
ZA - Sudafrica 2
AL - Albania 1
AZ - Azerbaigian 1
BO - Bolivia 1
BS - Bahamas 1
BY - Bielorussia 1
CH - Svizzera 1
CR - Costa Rica 1
DZ - Algeria 1
EC - Ecuador 1
GR - Grecia 1
IL - Israele 1
JO - Giordania 1
KG - Kirghizistan 1
KR - Corea 1
LU - Lussemburgo 1
MK - Macedonia 1
MY - Malesia 1
NO - Norvegia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
OM - Oman 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
VE - Venezuela 1
Totale 5.624
Città #
Fairfield 480
Woodbridge 374
Ashburn 260
Warsaw 247
Ann Arbor 241
Ferrara 223
Houston 218
Chandler 212
Santa Clara 204
Singapore 200
Seattle 188
Cambridge 177
Wilmington 154
Jacksonville 119
Menlo Park 98
Jakarta 57
New York 57
Beijing 56
Princeton 55
Shanghai 47
Izmir 45
Los Angeles 43
Milan 42
Nanjing 41
San Diego 28
Addison 24
Brussels 24
Bologna 21
Nanchang 20
Boardman 19
Dearborn 18
Helsinki 18
London 16
Dong Ket 15
St Louis 15
Ferrara di Monte Baldo 13
Munich 13
Redwood City 13
Falkenstein 12
Mountain View 11
Nuremberg 11
Brno 10
Falls Church 10
Bremen 9
Norwalk 9
Rome 9
Cagliari 8
Des Moines 8
Padova 8
Hong Kong 7
Jinan 7
San Mateo 7
Shenyang 7
Changsha 6
Toronto 6
Washington 6
Buenos Aires 5
Hebei 5
Jiaxing 5
Ottawa 5
Vienna 5
Auburn Hills 4
Dublin 4
Frankfurt am Main 4
Grassano 4
Guangzhou 4
Modena 4
Ningbo 4
Olomouc 4
Bari 3
Belo Horizonte 3
Bournemouth 3
Chicago 3
Hefei 3
Leawood 3
Lima 3
Orange 3
St Petersburg 3
São Paulo 3
Tappahannock 3
Tianjin 3
Waban 3
Ardabil 2
Aversa 2
Buffalo 2
Clifton 2
Contagem 2
Council Bluffs 2
Florence 2
Fort Huachuca 2
Haikou 2
Hyderabad 2
Islington 2
Kunming 2
Kuwait City 2
La Canada Flintridge 2
Lanzhou 2
Lauterbourg 2
Lugo 2
Madrid 2
Totale 4.378
Nome #
Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer’s disease 236
Sintesi di glicopeptidi mediante le reazioni tiol-ene/ino e studio della reattività di Umpolung di α-dichetoni 210
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism 186
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 175
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones 171
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction 154
Structure activity studies of nociceptin/orphanin FQ(1–13)-NH2 derivatives modified in position 5 147
Photoinduced addition of glycosyl thiols to alkynyl peptides: use of free-radical thiol-yne coupling for post-translational double-glycosylation of peptides 143
Modulation of the NOP receptor signaling affects resilience to acute stress 142
Structure-and conformation-Activity studies of nociceptin/orphanin FQ receptor dimeric ligands 141
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones 135
One-pot, two-step desymmetrization of symmetrical benzils catalyzed by the methylsulfinyl (dimsyl) anion 134
Synthesis of S-glycosyl amino acids and S-glycopeptides via photoinduced click thiol-ene coupling 121
Neuropeptide S receptor ligands: a patent review (2005-2016) 119
Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation 118
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 117
Peptide welding technology – A simple strategy for generating innovative ligands for G protein coupled receptors 114
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? 113
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening 113
Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology 113
Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor 112
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles 111
null 110
Tetrabranched Hetero-Conjugated Peptides as Bifunctional Agonists of the NOP and Mu Opioid Receptors 109
null 108
Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors 107
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 104
Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease 99
null 94
alpha-Diketones as acyl anion equivalents: a non-enzymatic thiamine-promoted route to aldehyde ketone coupling in PEG(400) as recyclable medium 94
Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5 93
The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation 93
null 92
Thiazolium-catalyzed intermolecular Stetter reaction of linear and cyclic alkyl α-diketones 83
alpha-Diketones as acyl anion equivalents: new enzymatic and non-enzymatic thiamine-promoted routes to aldehyde-ketone coupling 83
null 79
Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects 73
Synthesis of folic acid functionalized gold nanoclusters for targeting folate receptor-positive cells 68
Structure-Activity Relationship Studies on Oxazolo[3,4- a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent in Vivo Activity 63
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer 62
Reactivity of dialkyl and diaryl alpha-diketones with N-heterocyclic carbenes 62
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders 61
null 57
Novel Mixed NOP/Opioid Receptor Peptide Agonists 56
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 53
Cyclic peptides acting as allosteric inhibitors of human thymidylate synthase and cancer cell growth 52
Ageing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2 51
Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines 51
Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists 50
Probing the Effect of Sildenafil on Progesterone and Testosterone Production by an Intracellular FRET/BRET Combined Approach 48
Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase 47
Thermodynamic Stability and Speciation of Ga(III) and Zr(IV) Complexes with High-Denticity Hydroxamate Chelators 46
Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment 42
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative 41
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells 40
Dimethyl Sulfoxide and N,N-dimethylformamide as Umpolung Pre-catalysts in Cross Benzoin Reactions of alpha-Diketones with Aldehydes 36
Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease 36
Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19 33
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications 32
Unexpected reactivity of diaryl α-diketones with thiazolium carbenes: discovery of a novel multicomponent reaction for the facile synthesis of 1,4-thiazin-3-ones 27
Methylsulfinyl (Dimsyl) Anion as Umpolung Catalyst for the Chemoselective Cross Benzoin Reaction of α-Diketones with Aldehydes 27
Thiazolium-functionalized polystyrene monolithic microreactors for continuous-flow umpolung catalysis 27
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 27
Thiazolium-Functionalized Polystyrene Monolithic Microreactors for Continuous-Flow Umpolung Catalysis 23
Phosphodiesterase (PDE) 5 inhibitors sildenafil, tadalafil and vardenafil impact cAMP-specific PDE8 isoforms-linked second messengers and steroid production in a mouse Leydig tumor cell line 22
Synthesis of Chiral Ionic Liquids from Natural Monosaccharides 13
Probing non-peptide agonists binding at the human nociceptin/orphanin FQ receptor: a molecular modelling study 7
Totale 5.806
Categoria #
all - tutte 33.732
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.732


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020261 0 0 0 0 0 0 0 0 104 72 50 35
2020/20211.027 47 104 47 74 73 93 92 115 46 178 76 82
2021/2022690 31 91 147 32 27 33 43 26 33 51 34 142
2022/2023522 57 61 12 60 73 53 49 45 55 3 39 15
2023/2024481 50 47 24 25 25 81 25 47 22 24 14 97
2024/20251.154 67 38 160 96 162 154 51 95 331 0 0 0
Totale 5.806