PACIFICO, Salvatore
PACIFICO, Salvatore
Dipartimento di Scienze chimiche, farmaceutiche ed agrarie
A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism
2017 Fantinati, Anna; Bianco, Sara; Salvadori, Severo; Pacifico, Salvatore; Guerrini, Remo; Cerlesi, Maria Camilla; Trapella, Claudio; Calo', Girolamo
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells
2020 Marverti, Gaetano; Gozzi, Gaia; Maretti, Eleonora; Lauriola, Angela; Severi, Leda; Sacchetti, Francesca; Losi, Lorena; Pacifico, Salvatore; Ferrari, Stefania; Ponterini, Glauco; Leo, Eliana; Costi, Maria Paola; D'Arca, Domenico
Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation
file con accesso da definire2017 Rekik, Khaoula; Faria Da Silva, Raquel; Colom, Morgane; Pacifico, Salvatore; Zaveri, Nurulain T; Calo', Girolamo; Rampon, Claire; Frances, Bernard; Mouledous, Lionel
Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19
file con accesso da definire2024 Dallan, Beatrice; Proietto, Davide; De Laurentis, Martina; Gallerani, Eleonora; Martino, Mara; Ghisellini, Sara; Zurlo, Amedeo; Volpato, Stefano; Govoni, Benedetta; Borghesi, Michela; Albanese, Valentina; Appay, Victor; Bonnini, Stefano; Llewellyn-Lacey, Sian; Pacifico, Salvatore; Grumiro, Laura; Brandolini, Martina; Semprini, Simona; Sambri, Vittorio; Ladell, Kristin; Parry, Helen M.; Moss, Paul A. H.; Price, David A.; Null, Null; Barbieri, Elena; Bernardi, Tatiana; Boni, Michela; Dall'Olio, Linda; De Laurentis, Martina; Fiorini, Caterina; Fiorini, Michele; Govoni, Maurizio; Neri, Margherita; Palma, Fabio; Romagnoni, Franco; Caputo, Antonella; Gavioli, Riccardo; Nicoli, Francesco
Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease
2022 Cervellati, C; Vergallo, A; Trentini, A; Campo, G; Vieceli Dalla Sega, F; Bonaccorsi, G; Rosta, V; Renzini, C; Pacifico, S; Passaro, A; Hampel, H; Zuliani, G; Rizzo, P
Ageing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2
2023 Proietto, Davide; Dallan, Beatrice; Gallerani, Eleonora; Albanese, Valentina; Llewellyn-Lacey, Sian; Price, David A.; Appay, Victor; Pacifico, Salvatore; Caputo, Antonella; Nicoli, Francesco; Gavioli, Riccardo
alpha-Diketones as acyl anion equivalents: a non-enzymatic thiamine-promoted route to aldehyde ketone coupling in PEG(400) as recyclable medium
file con accesso da definire2011 Bortolini, Olga; Fantin, Giancarlo; Fogagnolo, Marco; Giovannini, Pier Paolo; Venturi, Valentina; Pacifico, Salvatore; Massi, Alessandro
alpha-Diketones as acyl anion equivalents: new enzymatic and non-enzymatic thiamine-promoted routes to aldehyde-ketone coupling
file con accesso da definire2011 Bortolini, Olga; Fantin, Giancarlo; Fogagnolo, Marco; Giovannini, Pier Paolo; Venturi, Valentina; Massi, Alessandro; Pacifico, Salvatore
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2
2020 Pacifico, S.; Ferrari, F.; Albanese, V.; Marzola, E.; Neto, J. A.; Ruzza, C.; Calo, G.; Preti, D.; Guerrini, R.
Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications
file con accesso da definire2024 Albanese, Valentina; Roccatello, Chiara; Pacifico, Salvatore; Guerrini, Remo; Preti, Delia; Gentili, Silvia; Tegoni, Matteo; Remelli, Maurizio; Bellotti, Denise; Amico, Jonathan; Gorgoni, Giancarlo; Cazzola, Emiliano
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth
2018 Saxena, P; Severi, L; Santucci, M; Taddia, L; Ferrari, S; Luciani, R; Marverti, G; Marraccini, C; Tondi, D; Mor, M; Scalvini, L; Vitiello, S; Losi, L; Fonda, S; Pacifico, S; Guerrini, R; D'Arca, D; Ponterini, G; Costi, Mp
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones?
file con accesso da definire2017 Sacchetti, Francesca; D'Arca, Domenico; Genovese, Filippo; Pacifico, Salvatore; Maretti, E; Hanuskova, M; Iannuccelli, V; Costi, Mp; Leo, E.
Cyclic peptides acting as allosteric inhibitors of human thymidylate synthase and cancer cell growth
2019 Pacifico, S.; Santucci, M.; Luciani, R.; Saxena, P.; Linciano, P.; Ponterini, G.; Lauriola, A.; D'Arca, D.; Marverti, G.; Guerrini, R.; Costi, M. P.
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones
2016 Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, Anna; Manfredini, Stefano; Pacifico, Salvatore; Liekens, Sandra; Balzarini, Jan
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
2022 Costantino, Luca; Ferrari, Stefania; Santucci, Matteo; H Salo-Ahen, Outi M; Carosati, Emanuele; Franchini, Silvia; Lauriola, Angela; Pozzi, Cecilia; Trande, Matteo; Gozzi, Gaia; Saxena, Puneet; Cannazza, Giuseppe; Losi, Lorena; Cardinale, Daniela; Venturelli, Alberto; Quotadamo, Antonio; Linciano, Pasquale; Tagliazucchi, Lorenzo; Gaetana Moschella, Maria; Guerrini, Remo; Pacifico, Salvatore; Luciani, Rosaria; Genovese, Filippo; Henrich, Stefan; Alboni, Silvia; Santarem, Nuno; da Silva Cordeiro, Anabela; Giovannetti, Elisa; J Peters, Godefridus; Pinton, Paolo; Rimessi, Alessandro; Cruciani, Gabriele; M Stroud, Robert; C Wade, Rebecca; Mangani, Stefano; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Paola Costi, Maria
Dimethyl Sulfoxide and N,N-dimethylformamide as Umpolung Pre-catalysts in Cross Benzoin Reactions of alpha-Diketones with Aldehydes
file con accesso da definire2013 Bortolini, Olga; Massi, Alessandro; Giovannini, Pier Paolo; Pacifico, Salvatore; Ragno, Daniele; Zaghi, Anna
Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction
2018 Morciano, Giampaolo; Preti, Delia; Pedriali, Gaia; Aquila, Giorgio; Missiroli, Sonia; Fantinati, Anna; Caroccia, Natascia; Pacifico, Salvatore; Bonora, Massimo; Talarico, Anna; Morganti, Claudia; Rizzo, Paola; Ferrari, Roberto; Wieckowski, Mariusz R.; Campo, Gianluca; Giorgi, Carlotta; Trapella, Claudio; Pinton, Paolo
Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening
2020 Breveglieri, G; Pacifico, Salvatore; Zuccato, Cristina; Cosenza, Lucia Carmela; Sultan, Shaiq; D'Aversa, Elisabetta; Gambari, Roberto; Preti, Delia; Trapella, Claudio; Guerrini, Remo; Borgatti, Monica
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders
2020 Asth, Laila; Tiago, Pamella R. F.; Costa, Layse R. F.; Holanda, Victor A. D.; Pacifico, Salvatore; Zaveri, Nurulain T.; Calo', Girolamo; Ruzza, Chiara; Gavioli, Elaine C.
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3
2017 Fantinati, Anna; Bianco, Sara; Cristofori, Virginia; Cavazzini, Alberto; Catani, Martina; Zanirato, Vinicio; Pacifico, Salvatore; Rimondi, Erika; Milani, Daniela; Voltan, Rebecca; Secchiero, Paola; Trapella, Claudio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism | 2017 | Fantinati, Anna; Bianco, Sara; Salvadori, Severo; Pacifico, Salvatore; Guerrini, Remo; Cerlesi, M...aria Camilla; Trapella, Claudio; Calo', Girolamo | |
| A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells | 2020 | Marverti, Gaetano; Gozzi, Gaia; Maretti, Eleonora; Lauriola, Angela; Severi, Leda; Sacchetti, Fra...ncesca; Losi, Lorena; Pacifico, Salvatore; Ferrari, Stefania; Ponterini, Glauco; Leo, Eliana; Costi, Maria Paola; D'Arca, Domenico | |
| Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation | 2017 | Rekik, Khaoula; Faria Da Silva, Raquel; Colom, Morgane; Pacifico, Salvatore; Zaveri, Nurulain T; ...Calo', Girolamo; Rampon, Claire; Frances, Bernard; Mouledous, Lionel | file con accesso da definire |
| Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19 | 2024 | Dallan, Beatrice; Proietto, Davide; De Laurentis, Martina; Gallerani, Eleonora; Martino, Mara; Gh...isellini, Sara; Zurlo, Amedeo; Volpato, Stefano; Govoni, Benedetta; Borghesi, Michela; Albanese, Valentina; Appay, Victor; Bonnini, Stefano; Llewellyn-Lacey, Sian; Pacifico, Salvatore; Grumiro, Laura; Brandolini, Martina; Semprini, Simona; Sambri, Vittorio; Ladell, Kristin; Parry, Helen M.; Moss, Paul A. H.; Price, David A.; Null, Null; Barbieri, Elena; Bernardi, Tatiana; Boni, Michela; Dall'Olio, Linda; De Laurentis, Martina; Fiorini, Caterina; Fiorini, Michele; Govoni, Maurizio; Neri, Margherita; Palma, Fabio; Romagnoni, Franco; Caputo, Antonella; Gavioli, Riccardo; Nicoli, Francesco | file con accesso da definire |
| Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease | 2022 | Cervellati, C; Vergallo, A; Trentini, A; Campo, G; Vieceli Dalla Sega, F; Bonaccorsi, G; Rosta, V...; Renzini, C; Pacifico, S; Passaro, A; Hampel, H; Zuliani, G; Rizzo, P | |
| Ageing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2 | 2023 | Proietto, Davide; Dallan, Beatrice; Gallerani, Eleonora; Albanese, Valentina; Llewellyn-Lacey, Si...an; Price, David A.; Appay, Victor; Pacifico, Salvatore; Caputo, Antonella; Nicoli, Francesco; Gavioli, Riccardo | |
| alpha-Diketones as acyl anion equivalents: a non-enzymatic thiamine-promoted route to aldehyde ketone coupling in PEG(400) as recyclable medium | 2011 | Bortolini, Olga; Fantin, Giancarlo; Fogagnolo, Marco; Giovannini, Pier Paolo; Venturi, Valentina;... Pacifico, Salvatore; Massi, Alessandro | file con accesso da definire |
| alpha-Diketones as acyl anion equivalents: new enzymatic and non-enzymatic thiamine-promoted routes to aldehyde-ketone coupling | 2011 | Bortolini, Olga; Fantin, Giancarlo; Fogagnolo, Marco; Giovannini, Pier Paolo; Venturi, Valentina;... Massi, Alessandro; Pacifico, Salvatore | file con accesso da definire |
| Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH2 | 2020 | Pacifico, S.; Ferrari, F.; Albanese, V.; Marzola, E.; Neto, J. A.; Ruzza, C.; Calo, G.; Preti, D....; Guerrini, R. | |
| Bifunctional octadentate pseudopeptides as Zirconium-89 chelators for immuno-PET applications | 2024 | Albanese, Valentina; Roccatello, Chiara; Pacifico, Salvatore; Guerrini, Remo; Preti, Delia; Genti...li, Silvia; Tegoni, Matteo; Remelli, Maurizio; Bellotti, Denise; Amico, Jonathan; Gorgoni, Giancarlo; Cazzola, Emiliano | file con accesso da definire |
| Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth | 2018 | Saxena, P; Severi, L; Santucci, M; Taddia, L; Ferrari, S; Luciani, R; Marverti, G; Marraccini, C;... Tondi, D; Mor, M; Scalvini, L; Vitiello, S; Losi, L; Fonda, S; Pacifico, S; Guerrini, R; D'Arca, D; Ponterini, G; Costi, Mp | |
| Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? | 2017 | Sacchetti, Francesca; D'Arca, Domenico; Genovese, Filippo; Pacifico, Salvatore; Maretti, E; Hanus...kova, M; Iannuccelli, V; Costi, Mp; Leo, E. | file con accesso da definire |
| Cyclic peptides acting as allosteric inhibitors of human thymidylate synthase and cancer cell growth | 2019 | Pacifico, S.; Santucci, M.; Luciani, R.; Saxena, P.; Linciano, P.; Ponterini, G.; Lauriola, A.; D...'Arca, D.; Marverti, G.; Guerrini, R.; Costi, M. P. | |
| Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones | 2016 | Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, Anna...; Manfredini, Stefano; Pacifico, Salvatore; Liekens, Sandra; Balzarini, Jan | |
| Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth | 2022 | Costantino, Luca; Ferrari, Stefania; Santucci, Matteo; H Salo-Ahen, Outi M; Carosati, Emanuele; F...ranchini, Silvia; Lauriola, Angela; Pozzi, Cecilia; Trande, Matteo; Gozzi, Gaia; Saxena, Puneet; Cannazza, Giuseppe; Losi, Lorena; Cardinale, Daniela; Venturelli, Alberto; Quotadamo, Antonio; Linciano, Pasquale; Tagliazucchi, Lorenzo; Gaetana Moschella, Maria; Guerrini, Remo; Pacifico, Salvatore; Luciani, Rosaria; Genovese, Filippo; Henrich, Stefan; Alboni, Silvia; Santarem, Nuno; da Silva Cordeiro, Anabela; Giovannetti, Elisa; J Peters, Godefridus; Pinton, Paolo; Rimessi, Alessandro; Cruciani, Gabriele; M Stroud, Robert; C Wade, Rebecca; Mangani, Stefano; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Paola Costi, Maria | |
| Dimethyl Sulfoxide and N,N-dimethylformamide as Umpolung Pre-catalysts in Cross Benzoin Reactions of alpha-Diketones with Aldehydes | 2013 | Bortolini, Olga; Massi, Alessandro; Giovannini, Pier Paolo; Pacifico, Salvatore; Ragno, Daniele; ...Zaghi, Anna | file con accesso da definire |
| Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction | 2018 | Morciano, Giampaolo; Preti, Delia; Pedriali, Gaia; Aquila, Giorgio; Missiroli, Sonia; Fantinati, ...Anna; Caroccia, Natascia; Pacifico, Salvatore; Bonora, Massimo; Talarico, Anna; Morganti, Claudia; Rizzo, Paola; Ferrari, Roberto; Wieckowski, Mariusz R.; Campo, Gianluca; Giorgi, Carlotta; Trapella, Claudio; Pinton, Paolo | |
| Discovery of novel fetal hemoglobin inducers for β-thalassemia by small chemical library screening | 2020 | Breveglieri, G; Pacifico, Salvatore; Zuccato, Cristina; Cosenza, Lucia Carmela; Sultan, Shaiq; D'...Aversa, Elisabetta; Gambari, Roberto; Preti, Delia; Trapella, Claudio; Guerrini, Remo; Borgatti, Monica | |
| Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders | 2020 | Asth, Laila; Tiago, Pamella R. F.; Costa, Layse R. F.; Holanda, Victor A. D.; Pacifico, Salvatore...; Zaveri, Nurulain T.; Calo', Girolamo; Ruzza, Chiara; Gavioli, Elaine C. | |
| Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 | 2017 | Fantinati, Anna; Bianco, Sara; Cristofori, Virginia; Cavazzini, Alberto; Catani, Martina; Zanirat...o, Vinicio; Pacifico, Salvatore; Rimondi, Erika; Milani, Daniela; Voltan, Rebecca; Secchiero, Paola; Trapella, Claudio |