DI VIRGILIO, Francesco
 Distribuzione geografica
Continente #
NA - Nord America 30.320
AS - Asia 13.788
EU - Europa 10.430
SA - Sud America 2.383
AF - Africa 187
OC - Oceania 54
Continente sconosciuto - Info sul continente non disponibili 19
Totale 57.181
Nazione #
US - Stati Uniti d'America 29.787
SG - Singapore 5.623
CN - Cina 4.083
DE - Germania 2.931
BR - Brasile 2.000
IT - Italia 1.751
UA - Ucraina 1.656
HK - Hong Kong 1.443
TR - Turchia 1.051
GB - Regno Unito 971
FI - Finlandia 761
RU - Federazione Russa 752
VN - Vietnam 719
SE - Svezia 402
PL - Polonia 356
MX - Messico 259
CA - Canada 224
ID - Indonesia 212
FR - Francia 200
IN - India 155
AR - Argentina 145
NL - Olanda 124
BE - Belgio 111
JP - Giappone 93
BD - Bangladesh 90
ZA - Sudafrica 86
ES - Italia 79
EC - Ecuador 77
IQ - Iraq 59
LT - Lituania 59
IE - Irlanda 46
AU - Australia 44
AT - Austria 39
CO - Colombia 37
CZ - Repubblica Ceca 34
CH - Svizzera 32
VE - Venezuela 29
PY - Paraguay 28
RO - Romania 28
IR - Iran 25
MA - Marocco 25
PE - Perù 25
DK - Danimarca 24
PK - Pakistan 24
IL - Israele 21
KE - Kenya 21
UZ - Uzbekistan 20
SA - Arabia Saudita 19
AE - Emirati Arabi Uniti 18
EG - Egitto 18
KR - Corea 18
CL - Cile 17
MY - Malesia 12
TN - Tunisia 12
EU - Europa 11
JO - Giordania 11
AZ - Azerbaigian 10
PA - Panama 10
TH - Thailandia 10
UY - Uruguay 10
GR - Grecia 9
DO - Repubblica Dominicana 8
KG - Kirghizistan 8
NP - Nepal 8
AL - Albania 7
BO - Bolivia 7
DZ - Algeria 7
HN - Honduras 7
KZ - Kazakistan 7
TW - Taiwan 7
BG - Bulgaria 6
BH - Bahrain 6
HR - Croazia 6
LB - Libano 6
LV - Lettonia 6
MD - Moldavia 6
NZ - Nuova Zelanda 6
A2 - ???statistics.table.value.countryCode.A2??? 5
EE - Estonia 5
GY - Guiana 5
JM - Giamaica 5
LU - Lussemburgo 5
PH - Filippine 5
PT - Portogallo 5
AM - Armenia 4
BB - Barbados 4
GE - Georgia 4
NG - Nigeria 4
OM - Oman 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
CI - Costa d'Avorio 3
CR - Costa Rica 3
ET - Etiopia 3
HU - Ungheria 3
PR - Porto Rico 3
SV - El Salvador 3
XK - ???statistics.table.value.countryCode.XK??? 3
BA - Bosnia-Erzegovina 2
Totale 57.144
Città #
Fairfield 3.222
Woodbridge 3.031
Singapore 3.016
Ashburn 2.681
Houston 2.134
Jacksonville 1.828
Chandler 1.735
Ann Arbor 1.603
Santa Clara 1.434
Hong Kong 1.429
Beijing 1.277
Wilmington 1.204
Seattle 1.173
Cambridge 941
Munich 696
Izmir 687
Ferrara 549
Nanjing 532
Dallas 446
Los Angeles 442
Princeton 441
Warsaw 313
New York 309
Boardman 304
San Diego 290
Ho Chi Minh City 266
Helsinki 265
Addison 209
Shanghai 209
São Paulo 199
Mexico City 177
Milan 172
Jakarta 162
Nanchang 151
Buffalo 149
Shenyang 146
Hanoi 141
Dearborn 134
Chicago 131
London 124
Tianjin 123
Bremen 115
Turku 114
Hefei 112
Hebei 107
Jiaxing 96
Brussels 91
Moscow 89
Redwood City 86
Brooklyn 85
Changsha 83
Frankfurt am Main 73
Mountain View 68
Tokyo 68
Norwalk 67
Montreal 66
Nuremberg 64
Manchester 61
Toronto 60
Zhengzhou 59
Falls Church 57
Denver 56
Dong Ket 56
San Francisco 56
Boston 55
Jinan 55
Chennai 54
Falkenstein 54
Rio de Janeiro 54
Rome 54
Atlanta 53
The Dalles 53
San Mateo 48
Orem 47
Bologna 46
Stockholm 45
Columbus 44
Guangzhou 44
Johannesburg 44
Amsterdam 43
Brasília 43
Council Bluffs 43
Kunming 43
Ningbo 41
Poplar 37
Orange 36
Curitiba 34
Auburn Hills 32
Phoenix 32
Des Moines 31
Hangzhou 31
Ottawa 31
Indiana 30
Augusta 29
Belo Horizonte 28
Salvador 28
Washington 28
Ankara 27
Baghdad 27
Campinas 27
Totale 37.715
Nome #
P2X7 receptor involvement in the pathogenesis of Hidradenitis Suppurativa 413
A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes. 367
A new luciferase target to the extracellular surface of the plasma membrane reveals a new pathway for ATP release in live intact cells. 332
I recettori purinergici P2 e le ectonucleotidasi: nuovi bersagli per lo sviluppo di farmaci anti-tumorali/P2 purinergic receptors and ectonucleotidases: novel targets for anti-cancer drugs (FIRB Accordi di programma n. RBAP11FXBC) 324
Increased level of extracellular ATP at tumor sites: In vivo imaging with plasma membrane luciferase 320
Characterization of P2X7 isoform B sheds light on the role of pore versus channel activity in P2X7 mediated life and death. 314
Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7 268
IL PROCESSO INFIAMMATORIO 259
Il recettore purinergico P2X7 come modulatore della fisiologia mitocondriale e del processo apoptotico 259
P2X7 targeting inhibits growth of human mesothelioma 254
A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion 249
1513A>C polymorphism in the P2X7 receptor gene in patients with papillary thyroid cancer: Correlation with histological variants and clinical parameters 243
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 238
Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death 237
Involvement of the purinergic P2X7 receptor in the formation of multinucleated giant cells 232
Extracellular ATP and P2 purinergic signalling in the tumour microenvironment 225
Amyloid beta-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine 225
Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus 222
Silencing of P2X7 receptor reduces B16 melanoma growth both in vitro and in vivo 220
p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner 214
ATP-mediated cytotoxicity in microglial cells 212
ATP release from chemotherapy-treated dying leukemia cells Elicits an immune suppressive effect by increasing regulatory T cells and Tolerogenic dendritic cells 211
Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles. 207
Role of P2X7 receptor in host response to melanoma 204
Expression of P2X7 receptor increases in vivo tumor growth 204
Activation of human eosinophils via P2 receptors: novel findings and future perspectives 199
P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration 198
Purinergic signaling in the immune system 197
P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia 193
Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes 191
The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration 190
5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes 189
Insight on P2X7 receptor role as oncogene 189
Stimulation of Purinergic Receptors Modulates Chemokine Expression in Human Keratinocytes 189
An ATP-activated channel is involved in mitogenic stimulation of human T lymphocytes 189
Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis 187
The antibiotic polymyxin B modulates P2X7 receptor function 187
The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination 187
Plasma P2X7 receptor correlation with plasma C-reactive protein in infectious diseases 187
ATP secreted by endothelial cells blocks CX 3CL1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y 11 receptor activation 186
The P2X7 receptor is a key modulator of aerobic glycolysis. 185
Extracellular ATP exerts opposite effects on activated and regulatory CD4+ T cells via purinergic P2 receptor activation 185
The antibiotic polymyxin B modulates P2X7 receptor function 183
Purinoceptor function in the immune system 183
Acute myeloid leukaemia:analysis of the expression of P2X7a and P2X7B isoforms 183
Increased sensitivity to extracellular ATP of fibroblasts from patients affected by systemic sclerosis 183
ATP receptors and giant cell formation 182
The P2X7 receptor : from ion channel to oncogene 182
The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein 182
Idiopatic inflammatory myopathies: serological and clinical correlations. Analysis of a monocentric series 181
Intracellular signalling in Te85 osteosarcoma cells expressing P2X7R isoforms A and B 179
Non-nucleotide agonists triggering P2X7 receptor activation and pore formation 179
Human primary keratinocytes express functional P2 receptors whose expression is modulated by inflammatory cytokines. 178
Extracellular nucleotides and nucleosides as signalling molecules 178
A defect in glycogen synthesis characterizes insulin resistance in hypertensive patients with type 2 diabetes 177
A new method for measuring local ATP release at the extracellular surface of live intact cells 177
La stimolazione del recettore P2X7 causa il rilascio di microvescicole contenenti IL-1 beta da parte di cellule dendritiche umane 175
Increased sensitivity of DMD lymphoblastoid cell to low doses of X irradiation 174
Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice 174
Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma 174
The human cathelicidin LL-37 modulates the activities of the P2X 7 receptor in a structure-dependent manner 174
Synthesis of conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor 173
Antibiotics and natural peptides as modulators of P2X7 functions 173
Blockade of P2X7 receptor inhibits formation of multinucleated giant cells. 173
Dr. Jekyll/Mr. Hyde: the dual role of extracellular ATP 173
P2X7A and B as novel biomarkers of acute myeloid leukemia response to chemotherapy and innovative therapeutic targets for the disease 173
Human keratinocytes express functional P2 receptors whose expression is modulated by inflammatory cytokines. 173
Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation 172
Dysfunctional inflammasome in Schnitzler's syndrome 172
Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors 171
The P2X7 Receptor in Infection and Inflammation 171
Extracellular purines, purinergic receptors and tumor growth 171
Altered expression and function of P2X7 receptorin patients affected by Systemic Lupus Erythematosus (SLE) 170
Structure-activity relationships around the KN-62, a potent antagonist of the P2X(7)receptor 169
Calcium and inositolphosphates in the activation of T cell-mediated cytotoxicity 169
Role of the P2X7 receptor in tumor-associated inflammation 167
The P2X7 Receptor Is Shed Into Circulation: Correlation With C-Reactive Protein Levels 167
Inhibitory effect of P2X7 receptor antagonists on in vivo tumor growth 166
P2 receptors in cancer progression and metastatic spreading 166
Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells 166
Detection of extracellular ATP in the tumor microenvironment, using the pmeLUC biosensor 166
ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment. 165
The P2X7 receptor: a key player in IL-1 processing and release 165
Alerting and tuning the immune response by extracellular nucleotides 164
P2X7 contemporarily impacts melanoma growth and anti-melanoma defense 163
Apoptosis is dependent on intracellular zinc and independent of intracellular calcium in lymphocytes 163
The P2X7 receptor-interleukin-1 liaison 163
Altered IL-1ß secretion in a patient affected by Schnitzler's syndrome 161
Multiple P2X receptors are involved in the modulation of apoptosis in human mesangial cells: evidence for a role of P2X4 161
P2X7 receptor as key modulator of PI3K/HIF1a/GSK3b metabolic pathway in neuroblastoma 160
Defective P2Y purinergic receptor function: A possible novel mechanism for impaired glucose transport 160
Purinergic regulation of airway inflammation 159
Expression of the P2X7 receptor and metabolic adaptation in serum and glucose deprivation 159
A ROLE FOR P2X7 RECEPTORS IN MICROGLIA PROLIFERATION 158
Purinergic P2Y(2) Receptors Promote Neutrophil Infiltration and Hepatocyte Death in Mice With Acute Liver Injury 158
“Hemophagocytic Lymphohistiocytosis after EBV reactivation and ibrutinib treatment in relapsed/refractory Chronic Lymphocytic Leukemia” 158
Synthesis, radiolabeling, and preliminary biological evaluation of [H-3]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl )-piperazine, a potent antagonist radioligand for the P2X(7) receptor 156
The P2 purinergic receptors of human dendritic cells: Identification and coupling to cytokine release 156
Increased reticular calcium content is related to NFATc1 activation and apoptosis resistance due to P2x7R expression 156
Hemophagocytic Lymphohistiocytosis in a Patient with Relapsed Chronic Lymphocytic Leukemia Treated with Ibrutinib 156
Totale 19.521
Categoria #
all - tutte 274.560
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 6.623
Totale 281.183


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20213.273 0 0 0 0 0 530 223 597 202 659 703 359
2021/20224.501 123 468 260 157 278 213 237 250 197 356 434 1.528
2022/20234.150 486 173 139 487 685 598 123 447 540 53 280 139
2023/20242.128 235 314 91 62 189 262 91 145 47 49 93 550
2024/20259.632 266 276 718 359 1.146 1.019 420 624 1.616 1.015 1.147 1.026
2025/202613.059 2.528 1.032 2.157 3.312 3.794 236 0 0 0 0 0 0
Totale 57.889