SECCHIERO, Paola
 Distribuzione geografica
Continente #
NA - Nord America 19.270
EU - Europa 4.846
AS - Asia 3.511
SA - Sud America 166
AF - Africa 24
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 4
Totale 27.833
Nazione #
US - Stati Uniti d'America 19.211
CN - Cina 1.608
IT - Italia 1.190
UA - Ucraina 1.004
SG - Singapore 914
DE - Germania 767
TR - Turchia 648
PL - Polonia 558
GB - Regno Unito 515
FI - Finlandia 254
SE - Svezia 230
BR - Brasile 152
ID - Indonesia 145
RU - Federazione Russa 72
FR - Francia 65
VN - Vietnam 59
CA - Canada 54
BE - Belgio 52
HK - Hong Kong 46
NL - Olanda 37
CZ - Repubblica Ceca 31
LT - Lituania 24
IN - India 15
IR - Iran 15
JP - Giappone 14
KR - Corea 12
AT - Austria 11
AU - Australia 11
IE - Irlanda 8
ES - Italia 7
TN - Tunisia 6
AR - Argentina 5
DZ - Algeria 5
EG - Egitto 5
RO - Romania 5
TW - Taiwan 5
BG - Bulgaria 4
MX - Messico 4
UZ - Uzbekistan 4
BD - Bangladesh 3
IL - Israele 3
IQ - Iraq 3
KE - Kenya 3
MY - Malesia 3
OM - Oman 3
VE - Venezuela 3
AZ - Azerbaigian 2
CL - Cile 2
CY - Cipro 2
EU - Europa 2
GE - Georgia 2
GR - Grecia 2
MA - Marocco 2
MD - Moldavia 2
PK - Pakistan 2
ZA - Sudafrica 2
A1 - Anonimo 1
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
CG - Congo 1
CH - Svizzera 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
LI - Liechtenstein 1
LU - Lussemburgo 1
MC - Monaco 1
MK - Macedonia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PE - Perù 1
PT - Portogallo 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
UY - Uruguay 1
Totale 27.833
Città #
Fairfield 2.805
Woodbridge 2.506
Houston 1.605
Ashburn 1.343
Jacksonville 1.164
Seattle 1.119
Chandler 1.099
Ann Arbor 1.062
Wilmington 988
Cambridge 952
Santa Clara 884
Singapore 681
Warsaw 556
Ferrara 511
Izmir 370
Nanjing 333
Beijing 283
Princeton 279
Boardman 229
San Diego 213
Jakarta 144
New York 137
Milan 136
Shanghai 130
Nanchang 106
Shenyang 104
Dearborn 98
Los Angeles 96
Tianjin 71
Falls Church 70
London 68
Changsha 63
Hebei 59
Dong Ket 56
Jiaxing 54
Mountain View 54
Bologna 52
Brussels 52
Bremen 47
San Mateo 40
Hong Kong 39
Kunming 39
Norwalk 39
Zhengzhou 38
Jinan 37
Redwood City 37
Auburn Hills 35
Munich 35
Helsinki 32
Tappahannock 32
Toronto 29
Frankfurt am Main 28
Brno 27
Addison 26
Orange 23
Guangzhou 21
Ottawa 21
Washington 20
Verona 19
Falkenstein 18
Ferrara di Monte Baldo 18
Ningbo 18
Leawood 17
Padova 17
Des Moines 16
Philadelphia 16
Sanayi 16
Scottsdale 16
Indiana 13
Nuremberg 13
Rome 13
Ardabil 12
Augusta 12
Changchun 12
Matera 12
Redmond 12
Haikou 11
Hounslow 11
Taizhou 11
Chicago 10
Hefei 10
Kilburn 9
Imola 8
Lappeenranta 8
Hangzhou 7
Lanzhou 7
Palermo 7
San Francisco 7
Dronten 6
Monmouth Junction 6
Prescot 6
São Paulo 6
Acton 5
Istanbul 5
Nam-gu 5
Parma 5
Taiyuan 5
Trieste 5
Ariano nel Polesine 4
Bari 4
Totale 21.615
Nome #
MDM2/X inhibitors under clinical evaluation: Perspectives for the management of hematological malignancies and pediatric cancer 195
Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model 190
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model 184
The anti-leukemic activity of sodium dichloroacetate in p53(mutated/null) cells is mediated by a p53-independent ILF3/p21 pathway 181
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 176
Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in Cognitive Impairment Diseases 173
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 172
The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles 170
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 164
Serum From Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells 161
Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia 161
Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1 160
Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells 151
The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias 149
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 149
Association of serum tumor necrosis factor-related apoptosis inducing ligand with body fat distribution as assessed by dual X-rays absorptiometry 148
Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging 148
Characterization of human herpesvirus 6 strains isolated from patients with exanthem subitum with or without cutaneous rash 145
The circulating levels of TRAIL are extremely low after delivery but rapidly recover in both mothers and newborns 145
Antiangiogenic activity of the MDM2 antagonist nutlin-3 143
CCR4+ skin-tropic phenotype as a feature of central memory CD8+ T cells in healthy subjects and psoriasis patients 140
Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities 139
Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature 136
Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-hodgkin's lymphoma xenografts 135
Nutlin-3 upregulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feed-back anti-apoptotic mechanism 134
In vivo anti-lymphoma activity of an agonistic human recombinant anti-TRAIL-R2 minibody. 134
Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis 134
The Sorafenib plus Nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of the FLT3 and p53 status 133
Clinical perspectives of TRAIL: Insights into central nervous system disorders 133
HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway 132
MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC 132
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease 131
Actively targeted nanocarriers for drug delivery to cancer cells 131
TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release 130
Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53(wild-type) JVM-2 But Not Towards p53(mutated) BJAB Leukemic Cells 130
Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA 130
In Vitro Characterization of Circulating Endothelial Progenitor Cells Isolated from Patients with Acute Coronary Syndrome 130
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment 130
Association between thyroid hormones and TRAIL 130
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes 129
Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol 129
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults 129
null 128
The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): Study protocol for a randomized controlled trial 128
HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells 127
TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress 126
Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL) 125
Plasma levels of soluble NCAM in multiple sclerosis 125
TNF-related apoptosis inducing ligand in ocular cancers and ocular diabetic complications 124
Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy 124
The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts 123
A set of NF-κB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer 123
Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity 123
Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors—implications for therapeutic potential 123
COVID-19 and individual genetic susceptibility/receptivity: Role of ACE1/ACE2 genes, immunity, inflammation and coagulation. might the double x-chromosome in females be protective against SARS-COV-2 compared to the single x-chromosome in males? 123
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets 123
null 121
TRAIL and osteoprotegerin: a role in endothelial physiopathology? 121
Anti-leukemic activity of Dasatinib in both p53(wild-type) and p53 (mutated) B malignant cells. 121
GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients 121
The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40. 121
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells 121
Cell-based therapies for diabetic complications. 121
Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye 121
Human herpesvirus 6: A survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders 120
Elevated levels of TRAIL in systemic lupus erythematosus are associated to the presence of anti-SSA/SSB antibodies. 120
Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells 120
Human Herpesvirus 7 infection induces profound cell cycle perturbations coupled to disregulation of cdc2 and cyclin B and polyploidization of CD4+ T Cells 120
Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication 120
Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells 120
Molecular targets for selective killing of TRAIL-resistant leukemic cells. 120
Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70 120
State of art and recent developments of anti-cancer strategies based on TRAIL 120
Is there any role for tumour necrosis factor related apoptosis inducing ligand–osteoprotegerin (TRAIL–OPG) interaction in rheumatoid arthritis? 119
Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity 119
Circulating levels of frizzled-related protein (FRZB) are increased in patients with early rheumatoid arthritis and decrease in response to disease-modifying antirheumatic drugs. 119
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women 119
Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis 118
Pegylated TRAIL retains anti-leukemic cytotoxicity and exhibits improved signal transduction activity with respect to TRAIL 117
Mesenchymal stem cells display hepato-protective activity in lymphoma bearing xenografts 117
Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress 115
Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis 115
Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells 114
MDM2 antagonist Nutlin-3 suppresses the proliferation and differentiation of human pre-osteoclasts through a p53-dependent pathway 114
Involvement of TRAIL/TRAIL-receptors in human intestinal cell differentiation 114
TRAIL, a New Weapon against Neointimal Hyperplasia 114
Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells 113
Cloning, restriction endonuclease mapping and partial sequence analysis of the genome of human herpesvirus 7 strain JI 113
Circulating TRAIL shows a significant post-partum decline associated to stressful conditions. 113
Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets. 113
MDM4 (MDMX) is overexpressed in chronic lymphocytic leukaemia (CLL) and marks a subset of p53wild-type CLL with a poor cytotoxic response to Nutlin-3. 113
JCV plus Patients with Inflammatory Bowel Disease show elevated plasma levels of MIG and SCF 113
Human herpesvirus type 7 in Hodgkin's disease 112
The tumour necrosis factor-related apoptosis inducing ligand-osteoprotegerin system in limited systemic sclerosis: a new disease marker? 112
Anticancer Activity of Aqueous Extracts from Asparagus officinalis L. Byproduct on Breast Cancer Cells 111
Human Colostrum and Breast Milk Contain High Levels of TNF-Related Apoptosis-Inducing Ligand (TRAIL). 110
Soluble TRAIL does not impair the anti-osteoclastic activity of osteoprotegerin: Letter to the editor 109
The calendar of cytokines: Seasonal variation of circulating cytokines in chronic venous insufficiency 109
Merkel-cell polyomavirus (MCPyV) is rarely associated to B-chronic lymphocytic leukemia (1 out of 50) samples and occurs late in the natural history of the disease 108
Trail down-regulates the release of osteoprotegerin (OPG) by primary stromal cells 107
Totale 13.039
Categoria #
all - tutte 136.764
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 136.764


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.114 0 0 0 0 0 0 0 658 520 542 234 160
2020/20214.565 292 379 171 560 344 475 240 541 147 671 469 276
2021/20222.870 87 314 220 115 161 164 175 165 101 233 334 801
2022/20232.687 296 131 95 311 408 394 116 245 358 48 160 125
2023/20241.451 162 182 53 38 105 201 45 148 30 30 59 398
2024/20253.008 214 192 533 310 851 515 285 108 0 0 0 0
Totale 28.343