SECCHIERO, Paola
 Distribuzione geografica
Continente #
NA - Nord America 23.332
AS - Asia 9.661
EU - Europa 6.408
SA - Sud America 1.761
AF - Africa 172
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 5
AN - Antartide 1
Totale 41.360
Nazione #
US - Stati Uniti d'America 22.967
SG - Singapore 3.958
CN - Cina 2.828
BR - Brasile 1.522
IT - Italia 1.496
DE - Germania 1.079
UA - Ucraina 1.052
HK - Hong Kong 956
TR - Turchia 696
GB - Regno Unito 682
PL - Polonia 654
VN - Vietnam 513
FI - Finlandia 333
RU - Federazione Russa 325
SE - Svezia 277
ID - Indonesia 193
CA - Canada 184
MX - Messico 146
FR - Francia 132
IN - India 121
AR - Argentina 109
ZA - Sudafrica 85
BD - Bangladesh 73
NL - Olanda 70
ES - Italia 68
JP - Giappone 65
BE - Belgio 52
LT - Lituania 38
CZ - Repubblica Ceca 37
EC - Ecuador 36
IQ - Iraq 33
AT - Austria 30
PK - Pakistan 25
VE - Venezuela 23
SA - Arabia Saudita 22
UZ - Uzbekistan 22
IR - Iran 19
AU - Australia 17
CO - Colombia 17
EG - Egitto 17
KR - Corea 17
MA - Marocco 17
AE - Emirati Arabi Uniti 15
CL - Cile 15
PY - Paraguay 15
DZ - Algeria 14
TN - Tunisia 14
TW - Taiwan 14
EE - Estonia 13
LK - Sri Lanka 13
UY - Uruguay 13
IE - Irlanda 11
AZ - Azerbaigian 10
KE - Kenya 10
IL - Israele 9
JO - Giordania 9
RO - Romania 9
BG - Bulgaria 8
CH - Svizzera 8
OM - Oman 8
DO - Repubblica Dominicana 7
JM - Giamaica 7
NP - Nepal 7
KG - Kirghizistan 6
AL - Albania 5
BO - Bolivia 5
CI - Costa d'Avorio 5
GE - Georgia 5
MY - Malesia 5
CR - Costa Rica 4
GR - Grecia 4
HN - Honduras 4
PE - Perù 4
PT - Portogallo 4
KZ - Kazakistan 3
NI - Nicaragua 3
RS - Serbia 3
SK - Slovacchia (Repubblica Slovacca) 3
TT - Trinidad e Tobago 3
BS - Bahamas 2
CY - Cipro 2
ET - Etiopia 2
EU - Europa 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LU - Lussemburgo 2
LV - Lettonia 2
MD - Moldavia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
QA - Qatar 2
SN - Senegal 2
SR - Suriname 2
TH - Thailandia 2
A1 - Anonimo 1
A2 - ???statistics.table.value.countryCode.A2??? 1
AO - Angola 1
AQ - Antartide 1
BB - Barbados 1
BF - Burkina Faso 1
Totale 41.337
Città #
Fairfield 2.805
Woodbridge 2.506
Ashburn 2.356
Singapore 2.114
Houston 1.632
Jacksonville 1.167
Seattle 1.136
Chandler 1.099
Ann Arbor 1.062
Wilmington 992
Cambridge 956
Hong Kong 949
Santa Clara 938
Beijing 931
Warsaw 641
Ferrara 572
Dallas 497
Izmir 370
Los Angeles 370
Nanjing 337
Princeton 279
New York 268
Munich 235
Boardman 229
San Diego 213
Ho Chi Minh City 178
Milan 162
Jakarta 157
São Paulo 157
Shanghai 137
Nanchang 107
Shenyang 104
Buffalo 100
Mexico City 100
Dearborn 98
Hanoi 93
London 92
Tianjin 90
Bologna 84
Chicago 81
Hefei 74
Turku 73
Denver 71
The Dalles 71
Falls Church 70
Brooklyn 68
Changsha 64
Montreal 62
Hebei 59
Dong Ket 56
Jiaxing 54
Moscow 54
Mountain View 54
Brussels 52
Johannesburg 51
San Francisco 51
Tokyo 51
Toronto 49
Stockholm 48
Bremen 47
Columbus 47
Poplar 46
Chennai 45
Frankfurt am Main 44
Zhengzhou 41
Atlanta 40
San Mateo 40
Boston 39
Kunming 39
Norwalk 39
Jinan 37
Redwood City 37
Council Bluffs 36
Auburn Hills 35
Helsinki 35
Orem 34
Rio de Janeiro 34
Tappahannock 32
Manchester 30
Matera 30
Phoenix 28
Brno 27
Guangzhou 27
Rome 27
Addison 26
Falkenstein 26
Nuremberg 26
Ankara 25
Porto Alegre 25
Brasília 24
Verona 24
Belo Horizonte 23
Orange 23
Washington 23
Curitiba 22
Philadelphia 22
Ottawa 21
Campinas 19
Guarulhos 19
Mumbai 19
Totale 28.809
Nome #
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model 259
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 255
Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in Cognitive Impairment Diseases 243
Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model 242
The anti-leukemic activity of sodium dichloroacetate in p53(mutated/null) cells is mediated by a p53-independent ILF3/p21 pathway 238
MDM2/X inhibitors under clinical evaluation: Perspectives for the management of hematological malignancies and pediatric cancer 236
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 231
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 229
Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells 218
Antiangiogenic activity of the MDM2 antagonist nutlin-3 215
Serum From Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells 215
Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia 214
Association of serum tumor necrosis factor-related apoptosis inducing ligand with body fat distribution as assessed by dual X-rays absorptiometry 211
CCR4+ skin-tropic phenotype as a feature of central memory CD8+ T cells in healthy subjects and psoriasis patients 209
A set of NF-κB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer 208
Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells 207
Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism 206
COVID-19 and individual genetic susceptibility/receptivity: Role of ACE1/ACE2 genes, immunity, inflammation and coagulation. might the double x-chromosome in females be protective against SARS-COV-2 compared to the single x-chromosome in males? 204
Anticancer Activity of Aqueous Extracts from Asparagus officinalis L. Byproduct on Breast Cancer Cells 204
Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye 203
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults 203
Characterization of human herpesvirus 6 strains isolated from patients with exanthem subitum with or without cutaneous rash 200
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 200
Association between thyroid hormones and TRAIL 197
Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis 197
The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles 195
Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging 194
The circulating levels of TRAIL are extremely low after delivery but rapidly recover in both mothers and newborns 194
Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1 194
GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients 193
Elevated levels of TRAIL in systemic lupus erythematosus are associated to the presence of anti-SSA/SSB antibodies 192
Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-hodgkin's lymphoma xenografts 192
Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53(wild-type) JVM-2 But Not Towards p53(mutated) BJAB Leukemic Cells 190
Actively targeted nanocarriers for drug delivery to cancer cells 190
Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70 189
Anti-leukemic activity of Dasatinib in both p53 wild-type and p53 mutated B malignant cells 186
The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias 186
Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature 186
The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts 185
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes 185
Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL) 185
TNF-related apoptosis inducing ligand in ocular cancers and ocular diabetic complications 185
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment 184
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets 184
Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol 183
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells 183
Clinical perspectives of TRAIL: Insights into central nervous system disorders 183
HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells 181
TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release 180
Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells 180
The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): Study protocol for a randomized controlled trial 180
In vivo anti-lymphoma activity of an agonistic human recombinant anti-TRAIL-R2 minibody. 178
TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress 178
Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy 178
Human Herpesvirus 7 infection induces profound cell cycle perturbations coupled to disregulation of cdc2 and cyclin B and polyploidization of CD4+ T Cells 177
HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway 177
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease 177
Is there any role for tumour necrosis factor related apoptosis inducing ligand–osteoprotegerin (TRAIL–OPG) interaction in rheumatoid arthritis? 175
MDM2 antagonist Nutlin-3 suppresses the proliferation and differentiation of human pre-osteoclasts through a p53-dependent pathway 174
Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis 174
Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity 174
Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity 172
Circulating levels of frizzled-related protein (FRZB) are increased in patients with early rheumatoid arthritis and decrease in response to disease-modifying antirheumatic drugs. 172
Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities 171
Circulating TRAIL shows a significant post-partum decline associated to stressful conditions 170
In Vitro Characterization of Circulating Endothelial Progenitor Cells Isolated from Patients with Acute Coronary Syndrome 169
Molecular targets for selective killing of TRAIL-resistant leukemic cells. 168
The Sorafenib plus Nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of the FLT3 and p53 status 168
Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress 168
Plasma levels of soluble NCAM in multiple sclerosis 167
Mesenchymal stem cells display hepato-protective activity in lymphoma bearing xenografts 166
MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC 165
Involvement of TRAIL/TRAIL-receptors in human intestinal cell differentiation 164
Engagement of CD28 modulates CXC chemokine receptor 4 surface expression in both resting and CD3-stimulated CD4+ T cells 164
Combined treatment of CpG-oligodeoxynucleotide with Nutlin-3 induces strong immune stimulation coupled to cytotoxicity in B-chronic lymphocytic leukemic (B-CLL) cells 163
Applications of nanoparticles in cancer medicine and beyond: optical and multimodal in vivo imaging, tissue targeting and drug delivery 162
State of art and recent developments of anti-cancer strategies based on TRAIL 161
A novel endovenous scaffold for the treatment of chronic venous obstruction in a porcine model: Histological and ultrastructural assessment 161
Eosinophils and purinergic signaling in health and disease 161
Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells 160
Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA 158
Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication 157
Pegylated TRAIL retains anti-leukemic cytotoxicity and exhibits improved signal transduction activity with respect to TRAIL 157
Cell-based therapies for diabetic complications. 157
Human Colostrum and Breast Milk Contain High Levels of TNF-Related Apoptosis-Inducing Ligand (TRAIL). 157
The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40. 156
Human herpesvirus 6: A survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders 155
Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets. 155
Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors—implications for therapeutic potential 155
Endothelial PDGF-BB produced ex vivo correlates with relevant hemodynamic parameters in patients affected by chronic venous disease 151
Chemoresistive Nanostructured Sensors for Tumor Pre-Screening 151
Reduced expression of cell cycle-associated genes in B lymphocytes purified from the peripheral blood of early-stage B chronic lymphocytic leukaemia patients 149
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women 149
Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells 149
Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells 148
MDM4 (MDMX) is overexpressed in chronic lymphocytic leukaemia (CLL) and marks a subset of p53wild-type CLL with a poor cytotoxic response to Nutlin-3. 148
TRAIL inhibits osteoclastic differentiation by counteracting RANKL-dependent p27Kip1 accumulation in pre-osteoclast precursors 148
Characterization Methods for Nanoparticle–Skin Interactions: An Overview 146
TRAIL and osteoprotegerin: a role in endothelial physiopathology? 146
Release of a specific set of proinflammatory adipokines by differentiating 3T3-L1 cells 146
Totale 18.255
Categoria #
all - tutte 194.682
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 194.682


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.819 0 0 0 0 0 475 240 541 147 671 469 276
2021/20222.870 87 314 220 115 161 164 175 165 101 233 334 801
2022/20232.687 296 131 95 311 408 394 116 245 358 48 160 125
2023/20241.451 162 182 53 38 105 201 45 148 30 30 59 398
2024/20256.733 214 192 533 310 851 515 285 389 1.154 632 957 701
2025/20269.859 1.835 862 1.785 2.370 2.681 326 0 0 0 0 0 0
Totale 41.927