SECCHIERO, Paola
 Distribuzione geografica
Continente #
NA - Nord America 23.578
AS - Asia 10.030
EU - Europa 6.459
SA - Sud America 1.804
AF - Africa 188
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 5
AN - Antartide 1
Totale 42.085
Nazione #
US - Stati Uniti d'America 23.199
SG - Singapore 4.166
CN - Cina 2.843
BR - Brasile 1.555
IT - Italia 1.512
DE - Germania 1.080
UA - Ucraina 1.053
HK - Hong Kong 962
TR - Turchia 697
GB - Regno Unito 694
PL - Polonia 662
VN - Vietnam 598
FI - Finlandia 333
RU - Federazione Russa 327
SE - Svezia 278
ID - Indonesia 194
CA - Canada 190
MX - Messico 152
FR - Francia 132
IN - India 130
AR - Argentina 114
ZA - Sudafrica 87
BD - Bangladesh 80
NL - Olanda 73
ES - Italia 71
JP - Giappone 68
BE - Belgio 52
IQ - Iraq 45
EC - Ecuador 38
LT - Lituania 38
CZ - Repubblica Ceca 37
PK - Pakistan 32
AT - Austria 30
UZ - Uzbekistan 25
VE - Venezuela 24
SA - Arabia Saudita 22
DZ - Algeria 19
IR - Iran 19
MA - Marocco 19
EG - Egitto 18
AE - Emirati Arabi Uniti 17
AU - Australia 17
CO - Colombia 17
KR - Corea 17
PY - Paraguay 16
CL - Cile 15
TN - Tunisia 15
TW - Taiwan 14
UY - Uruguay 14
EE - Estonia 13
LK - Sri Lanka 13
AZ - Azerbaigian 12
JO - Giordania 12
IE - Irlanda 11
IL - Israele 11
KE - Kenya 11
BG - Bulgaria 9
OM - Oman 9
RO - Romania 9
CH - Svizzera 8
JM - Giamaica 8
DO - Repubblica Dominicana 7
NP - Nepal 7
KG - Kirghizistan 6
AL - Albania 5
BO - Bolivia 5
CI - Costa d'Avorio 5
GE - Georgia 5
MY - Malesia 5
CR - Costa Rica 4
GR - Grecia 4
HN - Honduras 4
PE - Perù 4
PT - Portogallo 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
KZ - Kazakistan 3
MD - Moldavia 3
NI - Nicaragua 3
RS - Serbia 3
TT - Trinidad e Tobago 3
BS - Bahamas 2
BW - Botswana 2
CY - Cipro 2
ET - Etiopia 2
EU - Europa 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LB - Libano 2
LU - Lussemburgo 2
LV - Lettonia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PS - Palestinian Territory 2
QA - Qatar 2
SR - Suriname 2
TH - Thailandia 2
A1 - Anonimo 1
A2 - ???statistics.table.value.countryCode.A2??? 1
Totale 42.060
Città #
Fairfield 2.805
Woodbridge 2.506
Ashburn 2.433
Singapore 2.321
Houston 1.635
Jacksonville 1.167
Seattle 1.136
Chandler 1.099
Ann Arbor 1.062
Wilmington 992
Cambridge 956
Hong Kong 955
Santa Clara 941
Beijing 931
Warsaw 649
Ferrara 572
Dallas 497
Los Angeles 393
Izmir 370
Nanjing 339
New York 280
Princeton 279
Munich 235
Boardman 230
San Diego 213
Ho Chi Minh City 206
Milan 163
São Paulo 162
Jakarta 158
Shanghai 137
Hanoi 111
Nanchang 107
Shenyang 104
Mexico City 101
Buffalo 100
Dearborn 98
London 92
Tianjin 90
Bologna 86
Chicago 81
Denver 78
Hefei 74
Turku 73
The Dalles 72
Brooklyn 70
Falls Church 70
Montreal 65
Changsha 64
Hebei 59
Dong Ket 56
Jiaxing 54
Moscow 54
Mountain View 54
Poplar 54
Tokyo 54
Orem 53
Brussels 52
Johannesburg 52
San Francisco 51
Toronto 51
Stockholm 49
Chennai 48
Bremen 47
Columbus 47
Frankfurt am Main 44
Atlanta 42
Zhengzhou 42
Boston 41
San Mateo 40
Kunming 39
Norwalk 39
Council Bluffs 38
Jinan 37
Redwood City 37
Auburn Hills 35
Helsinki 35
Rio de Janeiro 35
Manchester 33
Phoenix 32
Tappahannock 32
San Jose 31
Matera 30
Guangzhou 28
Brno 27
Nuremberg 27
Rome 27
Addison 26
Ankara 26
Falkenstein 26
Porto Alegre 26
Brasília 24
Verona 24
Belo Horizonte 23
Orange 23
Washington 23
Curitiba 22
Philadelphia 22
Ottawa 21
Tashkent 21
Guarulhos 20
Totale 29.291
Nome #
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model 263
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 261
Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model 244
Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in Cognitive Impairment Diseases 244
The anti-leukemic activity of sodium dichloroacetate in p53(mutated/null) cells is mediated by a p53-independent ILF3/p21 pathway 241
MDM2/X inhibitors under clinical evaluation: Perspectives for the management of hematological malignancies and pediatric cancer 236
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 236
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 231
Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells 221
Serum From Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells 220
Antiangiogenic activity of the MDM2 antagonist nutlin-3 218
Association of serum tumor necrosis factor-related apoptosis inducing ligand with body fat distribution as assessed by dual X-rays absorptiometry 216
Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia 215
CCR4+ skin-tropic phenotype as a feature of central memory CD8+ T cells in healthy subjects and psoriasis patients 213
Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells 212
A set of NF-κB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer 212
Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism 210
Characterization of human herpesvirus 6 strains isolated from patients with exanthem subitum with or without cutaneous rash 209
Anticancer Activity of Aqueous Extracts from Asparagus officinalis L. Byproduct on Breast Cancer Cells 209
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults 207
Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye 206
COVID-19 and individual genetic susceptibility/receptivity: Role of ACE1/ACE2 genes, immunity, inflammation and coagulation. might the double x-chromosome in females be protective against SARS-COV-2 compared to the single x-chromosome in males? 206
Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis 202
Association between thyroid hormones and TRAIL 201
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 201
GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients 198
The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles 197
Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging 197
Elevated levels of TRAIL in systemic lupus erythematosus are associated to the presence of anti-SSA/SSB antibodies 196
The circulating levels of TRAIL are extremely low after delivery but rapidly recover in both mothers and newborns 196
Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1 196
Actively targeted nanocarriers for drug delivery to cancer cells 196
Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-hodgkin's lymphoma xenografts 195
Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53(wild-type) JVM-2 But Not Towards p53(mutated) BJAB Leukemic Cells 193
Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70 193
Anti-leukemic activity of Dasatinib in both p53 wild-type and p53 mutated B malignant cells 191
The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias 190
Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL) 190
The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts 189
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes 189
Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature 189
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment 188
TNF-related apoptosis inducing ligand in ocular cancers and ocular diabetic complications 187
Clinical perspectives of TRAIL: Insights into central nervous system disorders 187
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets 187
Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol 186
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells 186
HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells 185
Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells 184
TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release 183
TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress 183
Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy 183
Human Herpesvirus 7 infection induces profound cell cycle perturbations coupled to disregulation of cdc2 and cyclin B and polyploidization of CD4+ T Cells 182
In vivo anti-lymphoma activity of an agonistic human recombinant anti-TRAIL-R2 minibody. 181
The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): Study protocol for a randomized controlled trial 181
HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway 178
MDM2 antagonist Nutlin-3 suppresses the proliferation and differentiation of human pre-osteoclasts through a p53-dependent pathway 177
Is there any role for tumour necrosis factor related apoptosis inducing ligand–osteoprotegerin (TRAIL–OPG) interaction in rheumatoid arthritis? 177
Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity 177
Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis 177
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease 177
Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity 176
Circulating levels of frizzled-related protein (FRZB) are increased in patients with early rheumatoid arthritis and decrease in response to disease-modifying antirheumatic drugs. 174
Circulating TRAIL shows a significant post-partum decline associated to stressful conditions 174
Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress 173
The Sorafenib plus Nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of the FLT3 and p53 status 172
Molecular targets for selective killing of TRAIL-resistant leukemic cells. 171
In Vitro Characterization of Circulating Endothelial Progenitor Cells Isolated from Patients with Acute Coronary Syndrome 171
Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities 171
Mesenchymal stem cells display hepato-protective activity in lymphoma bearing xenografts 170
Involvement of TRAIL/TRAIL-receptors in human intestinal cell differentiation 169
Engagement of CD28 modulates CXC chemokine receptor 4 surface expression in both resting and CD3-stimulated CD4+ T cells 167
Plasma levels of soluble NCAM in multiple sclerosis 167
Applications of nanoparticles in cancer medicine and beyond: optical and multimodal in vivo imaging, tissue targeting and drug delivery 166
Eosinophils and purinergic signaling in health and disease 166
MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC 165
Combined treatment of CpG-oligodeoxynucleotide with Nutlin-3 induces strong immune stimulation coupled to cytotoxicity in B-chronic lymphocytic leukemic (B-CLL) cells 165
A novel endovenous scaffold for the treatment of chronic venous obstruction in a porcine model: Histological and ultrastructural assessment 165
State of art and recent developments of anti-cancer strategies based on TRAIL 162
Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells 160
Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA 160
Pegylated TRAIL retains anti-leukemic cytotoxicity and exhibits improved signal transduction activity with respect to TRAIL 159
The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40. 159
Cell-based therapies for diabetic complications. 159
Human Colostrum and Breast Milk Contain High Levels of TNF-Related Apoptosis-Inducing Ligand (TRAIL). 159
Human herpesvirus 6: A survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders 158
Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication 158
Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets. 156
Endothelial PDGF-BB produced ex vivo correlates with relevant hemodynamic parameters in patients affected by chronic venous disease 155
Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors—implications for therapeutic potential 155
Chemoresistive Nanostructured Sensors for Tumor Pre-Screening 154
Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells 153
Characterization Methods for Nanoparticle–Skin Interactions: An Overview 152
Cell cycle block by p53 acrivation reduces SARS-COV-2 release in infected alveolar basal epithelial A549-hACE2 cells 152
Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells 152
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women 152
TRAIL inhibits osteoclastic differentiation by counteracting RANKL-dependent p27Kip1 accumulation in pre-osteoclast precursors 151
Reduced expression of cell cycle-associated genes in B lymphocytes purified from the peripheral blood of early-stage B chronic lymphocytic leukaemia patients 151
Release of a specific set of proinflammatory adipokines by differentiating 3T3-L1 cells 150
Effects of hypoxia and bed rest on markers of cardiometabolic risk: Compensatory changes in circulating trail and glutathione redox capacity 150
Totale 18.574
Categoria #
all - tutte 196.339
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 196.339


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.819 0 0 0 0 0 475 240 541 147 671 469 276
2021/20222.870 87 314 220 115 161 164 175 165 101 233 334 801
2022/20232.687 296 131 95 311 408 394 116 245 358 48 160 125
2023/20241.451 162 182 53 38 105 201 45 148 30 30 59 398
2024/20256.733 214 192 533 310 851 515 285 389 1.154 632 957 701
2025/202610.584 1.835 862 1.785 2.370 2.681 1.051 0 0 0 0 0 0
Totale 42.652