SECCHIERO, Paola
 Distribuzione geografica
Continente #
NA - Nord America 18.004
EU - Europa 4.388
AS - Asia 2.607
SA - Sud America 21
OC - Oceania 8
AF - Africa 6
Continente sconosciuto - Info sul continente non disponibili 4
Totale 25.038
Nazione #
US - Stati Uniti d'America 17.993
CN - Cina 1.425
UA - Ucraina 1.004
IT - Italia 970
DE - Germania 681
TR - Turchia 630
PL - Polonia 558
GB - Regno Unito 477
SG - Singapore 339
FI - Finlandia 231
SE - Svezia 229
ID - Indonesia 66
FR - Francia 63
RU - Federazione Russa 63
VN - Vietnam 59
HK - Hong Kong 39
BE - Belgio 31
CZ - Repubblica Ceca 31
BR - Brasile 18
NL - Olanda 17
IR - Iran 15
IN - India 14
CA - Canada 10
AU - Australia 8
IE - Irlanda 8
EG - Egitto 5
ES - Italia 5
BG - Bulgaria 4
RO - Romania 4
IL - Israele 3
JP - Giappone 3
KR - Corea 3
TW - Taiwan 3
BD - Bangladesh 2
CL - Cile 2
EU - Europa 2
GE - Georgia 2
GR - Grecia 2
MD - Moldavia 2
MY - Malesia 2
A1 - Anonimo 1
A2 - ???statistics.table.value.countryCode.A2??? 1
AT - Austria 1
CH - Svizzera 1
CY - Cipro 1
DK - Danimarca 1
IQ - Iraq 1
KE - Kenya 1
LI - Liechtenstein 1
LU - Lussemburgo 1
MC - Monaco 1
MK - Macedonia 1
MX - Messico 1
SK - Slovacchia (Repubblica Slovacca) 1
VE - Venezuela 1
Totale 25.038
Città #
Fairfield 2.805
Woodbridge 2.506
Houston 1.605
Ashburn 1.332
Jacksonville 1.164
Seattle 1.119
Chandler 1.099
Ann Arbor 1.062
Wilmington 988
Cambridge 950
Warsaw 556
Ferrara 449
Izmir 369
Nanjing 333
Beijing 281
Princeton 279
Boardman 229
San Diego 213
Singapore 209
New York 137
Shanghai 125
Milan 120
Nanchang 106
Shenyang 104
Dearborn 98
Falls Church 70
Tianjin 70
Jakarta 65
Changsha 62
Hebei 59
Dong Ket 56
Jiaxing 54
Mountain View 54
London 49
Bremen 47
Los Angeles 43
San Mateo 40
Norwalk 39
Kunming 38
Zhengzhou 38
Redwood City 37
Hong Kong 36
Jinan 36
Auburn Hills 35
Tappahannock 32
Brussels 31
Brno 27
Addison 26
Bologna 26
Orange 23
Washington 20
Ferrara di Monte Baldo 18
Guangzhou 17
Leawood 17
Ningbo 17
Des Moines 16
Philadelphia 16
Sanayi 16
Scottsdale 16
Verona 16
Padova 15
Indiana 13
Ardabil 12
Augusta 12
Changchun 12
Redmond 12
Haikou 11
Helsinki 11
Hounslow 11
Taizhou 11
Chicago 10
Hefei 9
Kilburn 9
Munich 9
Imola 8
Hangzhou 7
Lanzhou 7
Palermo 7
San Francisco 7
Dronten 6
Lappeenranta 6
Monmouth Junction 6
Prescot 6
Acton 5
Parma 5
Trieste 5
Ariano nel Polesine 4
Cogorno 4
Forlì 4
Sofia 4
Tarcento 4
Toronto 4
Alcamo 3
Andover 3
Bari 3
Brescia 3
Catania 3
Chiswick 3
Comacchio 3
Edinburgh 3
Totale 19.780
Nome #
Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model 175
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model 168
The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles 166
The anti-leukemic activity of sodium dichloroacetate in p53(mutated/null) cells is mediated by a p53-independent ILF3/p21 pathway 166
Design, synthesis and biological characterization of novel mitochondria targeted dichloroacetate-loaded compounds with antileukemic activity 163
Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in Cognitive Impairment Diseases 159
Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 158
Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1 155
Expeditious Synthesis and Biological Characterization of Enantio-Enriched (-)-Nutlin-3 152
Serum From Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells 151
Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia 150
MDM2/X inhibitors under clinical evaluation: Perspectives for the management of hematological malignancies and pediatric cancer 148
The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias 144
Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells 138
Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging 137
The circulating levels of TRAIL are extremely low after delivery but rapidly recover in both mothers and newborns 136
HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts 136
Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities 133
Characterization of human herpesvirus 6 strains isolated from patients with exanthem subitum with or without cutaneous rash 131
null 128
Association of serum tumor necrosis factor-related apoptosis inducing ligand with body fat distribution as assessed by dual X-rays absorptiometry 128
Antiangiogenic activity of the MDM2 antagonist nutlin-3 128
Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature 128
MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC 127
Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-hodgkin's lymphoma xenografts 126
The Sorafenib plus Nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of the FLT3 and p53 status 125
Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53(wild-type) JVM-2 But Not Towards p53(mutated) BJAB Leukemic Cells 125
Nutlin-3 upregulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feed-back anti-apoptotic mechanism 124
In vivo anti-lymphoma activity of an agonistic human recombinant anti-TRAIL-R2 minibody. 124
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment 122
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease 122
null 121
TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release 121
Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis 121
Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA 121
HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway 120
In Vitro Characterization of Circulating Endothelial Progenitor Cells Isolated from Patients with Acute Coronary Syndrome 119
Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes 118
Clinical perspectives of TRAIL: Insights into central nervous system disorders 118
The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): Study protocol for a randomized controlled trial 118
Plasma levels of soluble NCAM in multiple sclerosis 118
Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol 117
Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity 117
Association between thyroid hormones and TRAIL 117
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults 117
HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells 116
The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40. 116
CCR4+ skin-tropic phenotype as a feature of central memory CD8+ T cells in healthy subjects and psoriasis patients 116
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets 116
TRAIL and osteoprotegerin: a role in endothelial physiopathology? 115
TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress 115
Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy 115
Human herpesvirus 6: A survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders 114
Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication 114
Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors—implications for therapeutic potential 114
Actively targeted nanocarriers for drug delivery to cancer cells 114
Cell-based therapies for diabetic complications. 113
TNF-related apoptosis inducing ligand in ocular cancers and ocular diabetic complications 113
Human Herpesvirus 7 infection induces profound cell cycle perturbations coupled to disregulation of cdc2 and cyclin B and polyploidization of CD4+ T Cells 112
Pegylated TRAIL retains anti-leukemic cytotoxicity and exhibits improved signal transduction activity with respect to TRAIL 112
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women 112
Elevated levels of TRAIL in systemic lupus erythematosus are associated to the presence of anti-SSA/SSB antibodies. 111
Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells 111
GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients 111
State of art and recent developments of anti-cancer strategies based on TRAIL 111
Molecular targets for selective killing of TRAIL-resistant leukemic cells. 110
The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts 109
Is there any role for tumour necrosis factor related apoptosis inducing ligand–osteoprotegerin (TRAIL–OPG) interaction in rheumatoid arthritis? 109
Cloning, restriction endonuclease mapping and partial sequence analysis of the genome of human herpesvirus 7 strain JI 109
Anti-leukemic activity of Dasatinib in both p53(wild-type) and p53 (mutated) B malignant cells. 109
Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL) 109
Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis 109
COVID-19 and individual genetic susceptibility/receptivity: Role of ACE1/ACE2 genes, immunity, inflammation and coagulation. might the double x-chromosome in females be protective against SARS-COV-2 compared to the single x-chromosome in males? 109
Circulating levels of frizzled-related protein (FRZB) are increased in patients with early rheumatoid arthritis and decrease in response to disease-modifying antirheumatic drugs. 108
JCV plus Patients with Inflammatory Bowel Disease show elevated plasma levels of MIG and SCF 108
TRAIL, a New Weapon against Neointimal Hyperplasia 108
A set of NF-κB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer 108
Human herpesvirus type 7 in Hodgkin's disease 107
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells 107
Conjunctival sac fluid contains elevated levels of soluble TRAIL: implications for the anti-tumoral surveillance of the anterior surface of the eye 107
Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells 106
Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells 106
null 105
Circulating TRAIL shows a significant post-partum decline associated to stressful conditions. 105
Mesenchymal stem cells display hepato-protective activity in lymphoma bearing xenografts 105
Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis 105
Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity 104
null 104
Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70 104
Soluble TRAIL does not impair the anti-osteoclastic activity of osteoprotegerin: Letter to the editor 103
Levels of circulating TNF-related apoptosis-inducing ligand in celiac disease 103
Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress 103
MDM2 antagonist Nutlin-3 suppresses the proliferation and differentiation of human pre-osteoclasts through a p53-dependent pathway 102
null 102
Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets. 102
Simultaneous determination of multiple cytokines reveals a pro-inflammatory and pro-angiogenic signature after major cardiothoracic surgery: potential role of C-reactive protein 102
MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer 102
The tumour necrosis factor-related apoptosis inducing ligand-osteoprotegerin system in limited systemic sclerosis: a new disease marker? 102
Merkel-cell polyomavirus (MCPyV) is rarely associated to B-chronic lymphocytic leukemia (1 out of 50) samples and occurs late in the natural history of the disease 102
Role of full-length osteoprotegerin in tumor cell biology. 101
Totale 12.001
Categoria #
all - tutte 101.621
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 101.621


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20206.095 862 222 215 909 440 678 655 658 520 542 234 160
2020/20214.565 292 379 171 560 344 475 240 541 147 671 469 276
2021/20222.870 87 314 220 115 161 164 175 165 101 233 334 801
2022/20232.687 296 131 95 311 408 394 116 245 358 48 160 125
2023/20241.451 162 182 53 38 105 201 45 148 30 30 59 398
2024/2025201 201 0 0 0 0 0 0 0 0 0 0 0
Totale 25.536