Mutagenicity of ethanolic extracts of oral carcinoma patients’ dentures.

Acrylic denture base material is in concact with orally transient mutagenic substances from tabacco, smoke and diet. These substances may become absorbed onto the denture surface, than their subsequent in situ desorption by alcohol may produce changed exposure patterns which might be a contributing factor in certain cases of oral and upper alimentary tract carcinogenesis. The purpose of this study was to examine whether worm dentures from human subjects affected by oral carcinoma contains adsorbed mutagens assessed by Salmonella/microsome mutagenicity test.