Non-natural axially and equatorially linked C-glycosyl alpha-amino acids (glycines, alanines, and CH2-serine isosteres) with either S or R alpha-configuration were prepared by D- and L-proline-catalyzed (de >95%) alpha-amination of C-glycosylalkyl aldehydes using dibenzyl azodicarboxylate as the electrophilic reagent.

General Synthesis of C-Glycosyl Amino Acids via Proline-Catalyzed Direct Electrophilic alpha-Amination of C-Glycosylalkyl Aldehydes

MASSI, Alessandro;DONDONI, Alessandro;NUZZI, Andrea
2008

Abstract

Non-natural axially and equatorially linked C-glycosyl alpha-amino acids (glycines, alanines, and CH2-serine isosteres) with either S or R alpha-configuration were prepared by D- and L-proline-catalyzed (de >95%) alpha-amination of C-glycosylalkyl aldehydes using dibenzyl azodicarboxylate as the electrophilic reagent.
2008
Massi, Alessandro; Dondoni, Alessandro; Nuzzi, Andrea
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/529928
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