The effects of several newly synthesized pyrazolo [4,3-d] pyrimidine-7-ones and pyrazolo-5-carboxamides on [3H]-flunitrazepam and [3H]-cyclohexyladenosine binding in rat cerebral cortex membranes have been studied. The compounds under examination, displaying affinities in the micromolar range for both benzodiazepine and adenosine A1 receptors, could be of interest in the study of a possible link between the two receptor systems.

Synthesis of 1H-pyrazolo[4,3-D]pyrimidine-7(6H)-ones and pyrazolo-5-carboxamides and interaction with benzodiazepine and adenosine-A1 receptors in rat cerebral-cortex

BARALDI PG
Primo
;
CASOLARI A;MANFREDINI S;ZANIRATO, Vinicio
Ultimo
1988

Abstract

The effects of several newly synthesized pyrazolo [4,3-d] pyrimidine-7-ones and pyrazolo-5-carboxamides on [3H]-flunitrazepam and [3H]-cyclohexyladenosine binding in rat cerebral cortex membranes have been studied. The compounds under examination, displaying affinities in the micromolar range for both benzodiazepine and adenosine A1 receptors, could be of interest in the study of a possible link between the two receptor systems.
1988
Baraldi, Pg; Casolari, A; Manfredini, S; Periotto, V; Florio, C; Traversa, V; Bertelli, Gm; Zanirato, Vinicio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/495760
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