Objective. To describe the presence of Propionibacterium acnes (P.acnes) in a series of patients with SAPHO syndrome in which a bone biopsy has been carried out and to discuss the results comparing them to the data described in literature. Methods. In 6 out of 56 patients with SAPHO syndrome, a bone biopsy from osteitic lesion was done. This invasive investigation was performed only in those cases in which it was necessary to clarify the diagnosis. Results. Of the 6 biopsies processed, P. acnes was isolated in only one case. No other infectious agents were identified. Conclusions. P. acnes is not often found in bone lesions of SAPHO syndrome. A bone biopsy may represent a procedure useful for corroborating the diagnosis or for excluding other diseases only in specific cases.
Propionibacterium acnes and SAPHO syndrome. a case report and literature review.
COLINA, Matteo;LO MONACO, Andrea;TROTTA, Francesco
2007
Abstract
Objective. To describe the presence of Propionibacterium acnes (P.acnes) in a series of patients with SAPHO syndrome in which a bone biopsy has been carried out and to discuss the results comparing them to the data described in literature. Methods. In 6 out of 56 patients with SAPHO syndrome, a bone biopsy from osteitic lesion was done. This invasive investigation was performed only in those cases in which it was necessary to clarify the diagnosis. Results. Of the 6 biopsies processed, P. acnes was isolated in only one case. No other infectious agents were identified. Conclusions. P. acnes is not often found in bone lesions of SAPHO syndrome. A bone biopsy may represent a procedure useful for corroborating the diagnosis or for excluding other diseases only in specific cases.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
