2-Acetylthiazole serves as a source of the alpha-hydroxypropanal beta-anion synton for the conversion of aldehydes into syn and anti alpha, gamma-dihydroxy homologues with three-more carbon atoms via a sequence consisting of: i) aldol condensation of the lithium enolate derived from thiazole; ii) reduction of hydroxy ketone; iii) thiazole to formyl unmasking.

2-ACETYLTHIAZOLE AS A 3-CARBON HOMOLOGATING REAGENT OF ALDEHYDES - APPLICATION TOWARD THE SYNTHESIS OF AMINO HEXOSES FROM L-SERINAL

DONDONI, Alessandro;FANTIN, Giancarlo;FOGAGNOLO, Marco
1989

Abstract

2-Acetylthiazole serves as a source of the alpha-hydroxypropanal beta-anion synton for the conversion of aldehydes into syn and anti alpha, gamma-dihydroxy homologues with three-more carbon atoms via a sequence consisting of: i) aldol condensation of the lithium enolate derived from thiazole; ii) reduction of hydroxy ketone; iii) thiazole to formyl unmasking.
1989
Dondoni, Alessandro; Fantin, Giancarlo; Fogagnolo, Marco
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/461184
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 17
  • ???jsp.display-item.citation.isi??? 17
social impact