Brain networkness: from dynamics to function and dysfunction reply to comments on:" Does the brain behave like a (complex) network? I. Dynamics"

The question of whether the brain behaves like a network can be formulated in various ways, e.g. in terms of network relevance (is the network structure relevant, in some sense, to brain anatomy and activity?) or of observability and controllability (does the network structure retain sufficient information to adequately reconstruct the full system dynamics? Can brain activity be controlled by acting on its network structure?). In [1], we termed networkness the ways in which network structure explains brain anatomy and dynamics and ultimately its behaviour and set out to discuss how and to what extent the brain, particularly when thought of as a dynamical system, can genuinely be understood to behave as a network. Five commentaries to the target article addressed from different angles several key aspects of brain networkness, which we set out to discuss below.