It is recognized that social heterogeneities in terms of the contact distribution have a strong influence on the spread of infectious diseases. Nevertheless, few data are available on the group composition of social contacts, and their statistical description does not possess universal patterns and may vary spatially and temporally. It is therefore essential to design robust control strategies,mimicking the effects of non-pharmaceutical interventions, to limit efficiently the number of infected cases. In this work, starting from a recently introduced kinetic model for epidemiological dynamics that takes into account the impact of social contacts of individuals, we consider an uncertain contact formation dynamics leading to slim-tailed as well as fat-tailed distributions of contacts. Hence, we analyse the effects of an optimally robust control strategy of the systemof agents. Thanks to classical methods of kinetic theory, we couple uncertainty quantification methods with the introduced mathematical model to assess the effects of social limitations. Finally, using the proposed modeling approach and starting from available data, we show the effectiveness of the proposed selective measures to dampen uncertainties together with the epidemic trends.

On the optimal control of kinetic epidemic models with uncertain social features

Franceschi, Jonathan
Primo
;
Medaglia, Andrea
Secondo
;
Zanella, Mattia
Ultimo
2024

Abstract

It is recognized that social heterogeneities in terms of the contact distribution have a strong influence on the spread of infectious diseases. Nevertheless, few data are available on the group composition of social contacts, and their statistical description does not possess universal patterns and may vary spatially and temporally. It is therefore essential to design robust control strategies,mimicking the effects of non-pharmaceutical interventions, to limit efficiently the number of infected cases. In this work, starting from a recently introduced kinetic model for epidemiological dynamics that takes into account the impact of social contacts of individuals, we consider an uncertain contact formation dynamics leading to slim-tailed as well as fat-tailed distributions of contacts. Hence, we analyse the effects of an optimally robust control strategy of the systemof agents. Thanks to classical methods of kinetic theory, we couple uncertainty quantification methods with the introduced mathematical model to assess the effects of social limitations. Finally, using the proposed modeling approach and starting from available data, we show the effectiveness of the proposed selective measures to dampen uncertainties together with the epidemic trends.
2024
Franceschi, Jonathan; Medaglia, Andrea; Zanella, Mattia
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2614952
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