Editorial: Women in bone research

This Research Topic, “Women in Bone Research,” presents 15 original articles led by women scientists, spanning basic and clinical advances in musculoskeletal research. The basic science contributions explore critical areas such as osteocyte biology, aging-related bone loss, tissue engineering, glucocorticoid effects, and sex-specific gene expression, with studies highlighting key regulators like FABP5, Klotho, and various microenvironmental and hormonal factors. Notably, innovative models and natural compounds were employed to investigate osteogenesis, inflammation, and senescence. Clinical studies addressed risk factors for low bone mineral density (BMD), including fat content, gestational diabetes, lipid profiles, genetic variants, and hormonal influences. Interventional findings suggest that Chinese fitness exercises and extracorporeal shockwave therapy may offer supportive benefits in bone health and fracture healing. Additionally, studies on bone metastases of unknown origin and reproductive hormone links to back pain underscore the complexity of bone-related pathologies. Overall, the collection underscores the significant contributions of women in bone research, emphasizing sex differences, aging, and translational potential. This initiative aims to inspire continued excellence and gender equity in the field of skeletal biology.