Multiple squamous cell carcinomas arising from ulcerative lichen planus of the sole

Neoplastic transformation has been reported in lichen planus (LP), with the development of squamous cell carcinomas (SCC) in 0.3-3% of cases, especially when the disease involves the oral cavity. When the skin is affected, the malignancy risk is very low and is associated with the hypertrophic form, with a predilection for the lower limbs. Ulcerative LP has also been reported to be associated with degeneration in SCC, including some cases of the low-grade variant verrucous carcinoma. We report an emblematic case.