Thecombinationofunconventionalfabricationtechnology andbiomaterialsallowsbothtorealizestate-of-the-artdeviceswithhighlycontrolledlateralfeaturesandperformances andtostudythemainpropertiesofthebiomoleculesthemselvesbyoperatingatascalelevelcomparablewiththeone crucialfortheiractivity.Softlithographyandmicrofluidic devicesofferatool-boxbothtostudybiomoleculesunder highlyconfinedenvironments[1]andtofabricateinaneasy waytopographicfeatureswithlocallycontrolledmechanical andchemicalsurfaceproperties,thusleadingtoafiner controloftheinterplayofmechanicsandchemistry.Iwill presentanapplicationofthistechnologytothecontrolofcell fatethatisbecomingakeyissueinregenerativemedicinein theperspectiveofgeneratingnovelartificialtissues.
Abstracts of the 8th EBSA (European Biophysical Societies Association) European Biophysics Congress. August 23-27, 2011. Budapest, Hungary
Michele Bianchi;Pierpaolo Greco;Fabio Biscarini
2011
Abstract
Thecombinationofunconventionalfabricationtechnology andbiomaterialsallowsbothtorealizestate-of-the-artdeviceswithhighlycontrolledlateralfeaturesandperformances andtostudythemainpropertiesofthebiomoleculesthemselvesbyoperatingatascalelevelcomparablewiththeone crucialfortheiractivity.Softlithographyandmicrofluidic devicesofferatool-boxbothtostudybiomoleculesunder highlyconfinedenvironments[1]andtofabricateinaneasy waytopographicfeatureswithlocallycontrolledmechanical andchemicalsurfaceproperties,thusleadingtoafiner controloftheinterplayofmechanicsandchemistry.Iwill presentanapplicationofthistechnologytothecontrolofcell fatethatisbecomingakeyissueinregenerativemedicinein theperspectiveofgeneratingnovelartificialtissues.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
