Melissa Poh and colleagues (June 18, p 2122)1 show that induction of telom- erase activity in vascular cells by trans- duction of the reverse transcriptase subunit of human telomerase (hTERT) enables successful culture of engi- neered autologous blood vessels. Although the results are encouraging in www.thelancet.com Vol366 September10,2005 891 Correspondence terms of functional properties of the engineered blood vessels, we would like to add a word of caution regarding use of this approach in tissue-engineering protocols on the basis of our extensive experience of using hTERT to generate osteoblastic cells for bone generation.
Blood vessels engineered from human cells
Burns J;
2005
Abstract
Melissa Poh and colleagues (June 18, p 2122)1 show that induction of telom- erase activity in vascular cells by trans- duction of the reverse transcriptase subunit of human telomerase (hTERT) enables successful culture of engi- neered autologous blood vessels. Although the results are encouraging in www.thelancet.com Vol366 September10,2005 891 Correspondence terms of functional properties of the engineered blood vessels, we would like to add a word of caution regarding use of this approach in tissue-engineering protocols on the basis of our extensive experience of using hTERT to generate osteoblastic cells for bone generation.File in questo prodotto:
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