A case report of giant hepatic hemangioma spontaneous regression in adult, non-cirrhotic patient and literature review

Hepatic hemangiomas (HHs) are defines as “giant” when are larger than 4 cm. The following case is reviewed due its unusual evolution. A case of 64-year-old woman was found at CT scan to have a “giant” HH (>20 cm in diameter). In 2015 (8 years after initial diagnosis), in the absence of treatments, abdominal CT scan highlighted the initial spontaneous regression of the HH, that progressed over time. Management of giant hemangiomas remains debated. Surgery should be restricted to specific situations, depending on growth pattern, symptom persistence, risk of complications and patient anxiety. Usually HHs remain stable in size over time and only a prolonged clinical and radiological follow-up is advised. The commonly known natural history of HHs in non-cirrhotics do not include decrease in size or regression. Clearly documented cases of spontaneous regression of giant HHs in non-cirrhotic adult patients have not yet been reported.