Takotsubo syndrome, neurological disorders, and sex: a dangerous liaison?

Since the dawn of the XX century, some epidemiological observations indicated different patterns among males and females either for health and mortality, as summarized by Judith Lorber and Lisa Jean Moore in the statement “women get sicker, but men die quicker”. Takotsubo syndrome, benign disease for females but life-threatening for males, is a perfect topic for gender-specific medicine, a novel eye looking at the differences among males and females in terms of prevention, signs and symptoms, therapy, and outcome of different diseases, in the view of a personalized and optimized comprehensive approach.