Objective:Several studies suggest that transcutaneous electrical stimulation (TENS) can have a variety of effects on the central nervoussystem (CNS). In this study, we tried to replicate the physiological effects of TENS and to explore its effects on intracortical circuits.Methods:We used transcranial magnetic stimulation (TMS) and spinal reflex testing to examine excitability of intracortical and spinalcord circuits before and after a 30-min period of TENS over the flexor carpi radialis (FCR) muscle. We measured the amplitude of TMS-evoked muscle responses (MEP), short interval intracortical inhibition (SICI), intracortical facilitation (ICF) and cortical antagonistinhibition (CAI) in flexor and extensor carpial radialis (FCR, ECR) muscles as well as spinal reciprocal inhibition (RI) and presynapticinhibition (PI) from ECR to FCR.Results:TENS had no significant effect on any of these measures apart from a reduction in median nerve induced facilitation of FCRwhen testing CAI.Conclusions:When compared with previous studies, our results suggest that the effects of TENS are highly variable and unreliable, likelyby the difficulty in defining precise parameters of stimulation in individual subjects.Significance:Care should be taken in assuming that effects after TENS observed in small populations of subjects will apply equally to awider population.
How repeatable are the physiological effects of TENS?
Koch G;
2008
Abstract
Objective:Several studies suggest that transcutaneous electrical stimulation (TENS) can have a variety of effects on the central nervoussystem (CNS). In this study, we tried to replicate the physiological effects of TENS and to explore its effects on intracortical circuits.Methods:We used transcranial magnetic stimulation (TMS) and spinal reflex testing to examine excitability of intracortical and spinalcord circuits before and after a 30-min period of TENS over the flexor carpi radialis (FCR) muscle. We measured the amplitude of TMS-evoked muscle responses (MEP), short interval intracortical inhibition (SICI), intracortical facilitation (ICF) and cortical antagonistinhibition (CAI) in flexor and extensor carpial radialis (FCR, ECR) muscles as well as spinal reciprocal inhibition (RI) and presynapticinhibition (PI) from ECR to FCR.Results:TENS had no significant effect on any of these measures apart from a reduction in median nerve induced facilitation of FCRwhen testing CAI.Conclusions:When compared with previous studies, our results suggest that the effects of TENS are highly variable and unreliable, likelyby the difficulty in defining precise parameters of stimulation in individual subjects.Significance:Care should be taken in assuming that effects after TENS observed in small populations of subjects will apply equally to awider population.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
