Pleomorphic adenoma (also known as mixed tumour) is the most common neoplasm of the salivary glands. it is usually a benign, slow-growing and well-circumscribed lesion. Metastasizing pleomorphic salivary adenoma is extremely rare, occurring in less than 1% of patients with pleomorphic adenoma. There are very few reports of a subset of these tumours metastasizing to distant sites without undergoing malignant transformation. There are as yet no statistics for this pathology - some aspects continue to be controversial and any patient may represent a diagnostic dilemma for the surgical oncologist and the cancer pathologist. A definitive diagnosis usually requires radical surgery, if possible. We present a review of the literature and an unusual case of a large liver mass found incidentally in an 87-year-old female. The patient was eligible for surgery and a successful liver resection was performed. The liver tumour was found to be a very large metastasis of pleomorphic adenoma with unharmed resection margins. This diagnosis is extremely rare and our patient seems to represent the oldest case described to date.
A late solitary liver metastasis from pleomorphic salivary adenoma
Nicolò FABBRI
Primo
;Gloria FERROCCI;Giancarlo PANSINIUltimo
2019
Abstract
Pleomorphic adenoma (also known as mixed tumour) is the most common neoplasm of the salivary glands. it is usually a benign, slow-growing and well-circumscribed lesion. Metastasizing pleomorphic salivary adenoma is extremely rare, occurring in less than 1% of patients with pleomorphic adenoma. There are very few reports of a subset of these tumours metastasizing to distant sites without undergoing malignant transformation. There are as yet no statistics for this pathology - some aspects continue to be controversial and any patient may represent a diagnostic dilemma for the surgical oncologist and the cancer pathologist. A definitive diagnosis usually requires radical surgery, if possible. We present a review of the literature and an unusual case of a large liver mass found incidentally in an 87-year-old female. The patient was eligible for surgery and a successful liver resection was performed. The liver tumour was found to be a very large metastasis of pleomorphic adenoma with unharmed resection margins. This diagnosis is extremely rare and our patient seems to represent the oldest case described to date.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.