A large observational study found an association between the use of the nucleoside reverse transcriptase inhibitor abacavir and an increase of cardiovascular risk in HIV-1infected patients. Since then, different studies have reported con- troversial results: some cohort studies seemed to confirm the observation, whereas other more recent analyses and a meta-analysis seem to contradict this hypothesis.
Exposure to abacavir and biomarkers of cardiovascular disease in HIV-1-infected patients on suppressive antiretroviral therapy: A longitudinal study
Segala DMembro del Collaboration Group
2012
Abstract
A large observational study found an association between the use of the nucleoside reverse transcriptase inhibitor abacavir and an increase of cardiovascular risk in HIV-1infected patients. Since then, different studies have reported con- troversial results: some cohort studies seemed to confirm the observation, whereas other more recent analyses and a meta-analysis seem to contradict this hypothesis.File in questo prodotto:
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