This study describes the preparation, characterization, and first biologic evaluation in rats of radiolabelled nanostructured lipid carriers (NLC) especially designed for in vivo tomographic study.A technological study was conducted in order to associate 99mTc within the matrix of NLC. At this aim 99mTc complexes containing a terminal Tc:Nmultiple bond ([99mTc]N-DBODC2) have been encapsulated.
In vivo evaluation of nanostructured lipid labelled with 99mTc
ESPOSITO, Elisabetta;BOSCHI, Alessandra;RAVANI, Laura;CORTESI, Rita;CONTADO, Catia;DI DOMENICO, Giovanni;NASTRUZZI, Claudio;GIGANTI, Melchiore;PASQUALI, Micol;MARTINI, Petra;UCCELLI, Licia;CONTADO, Cristiano
2015
Abstract
This study describes the preparation, characterization, and first biologic evaluation in rats of radiolabelled nanostructured lipid carriers (NLC) especially designed for in vivo tomographic study.A technological study was conducted in order to associate 99mTc within the matrix of NLC. At this aim 99mTc complexes containing a terminal Tc:Nmultiple bond ([99mTc]N-DBODC2) have been encapsulated.File in questo prodotto:
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