Background: Allergic rhinitis (AR) is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the nasal mucosa. This study was designed to investigate the role of nasal mucosa temperature in AR. Methods: We investigated the relationship between eosinophilic infiltration, nasal obstruction, and nasal mucosa temperature in 35 children with rhinitis aged 6-12 years. Results: A significant relationship was shown between nasal temperature values and eosinophil infiltration at nasal cytology (p - 0.01). Nasal temperature was also significantly associated with nasal obstruction, assessed in terms of nasal volume (Vol [2-5 cm]; p - 0.05) and minimum cross-sectional area (p - 0.01). No significant correlation emerged between the degree of nasal obstruction and presence of eosinophils at nasal cytology (p - 0.05). Conclusion: These results suggest a relationship between nasal temperature and nasal mucosa inflammation and obstruction. (ClinicalTrials....
Nasal mucosa temperature as a marker of disease in children with allergic rhinitis
PERONI, Diego;
2012
Abstract
Background: Allergic rhinitis (AR) is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the nasal mucosa. This study was designed to investigate the role of nasal mucosa temperature in AR. Methods: We investigated the relationship between eosinophilic infiltration, nasal obstruction, and nasal mucosa temperature in 35 children with rhinitis aged 6-12 years. Results: A significant relationship was shown between nasal temperature values and eosinophil infiltration at nasal cytology (p - 0.01). Nasal temperature was also significantly associated with nasal obstruction, assessed in terms of nasal volume (Vol [2-5 cm]; p - 0.05) and minimum cross-sectional area (p - 0.01). No significant correlation emerged between the degree of nasal obstruction and presence of eosinophils at nasal cytology (p - 0.05). Conclusion: These results suggest a relationship between nasal temperature and nasal mucosa inflammation and obstruction. (ClinicalTrials....I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
