We compared TcN-NOET [bis(N-ethoxy, N-ethyl dithiocarbamato)nitrido 99mTc] and 201TI images to estimate the utility of this compound in the detection of coronary artery disease (CAD). Methods: Twenty-five patients undergoing cardiac catheterization had stress-redistribution-reinjection 201TI SPECT imaging, stress-delayed (2, 4 and 6 hr postinjection) and rest-delayed (4 hr postinjection) TcN-NOET SPECT imaging. Results: Nineteen patients had coronary stenosis ≥50% and six were normal. Stress TcN-NOET and 201TI imaging were concordant for the presence of CAD in 22/25 patients (88%, κ = 0.76 ± 0.20). The overall sensitivity of TcN-NOET SPECT imaging was 74% (14/19 patients) and 68% (13/19 patients) for 201TI SPECT imaging. The specificity was 100% (6/6 patients) for both techniques. The overall agreement of TcN-NOET and 201TI for the presence of disease in individual coronary arteries was 96% (72/75 arteries, κ = 0.92 ± 0.16). Segmental analysis of stress images showed a concordance in 2...
Myocardial perfusion imaging with Technetium-99m-Tc NOET: Comparison with Thallium-201 and coronary angiography
GIGANTI, Melchiore;
1995
Abstract
We compared TcN-NOET [bis(N-ethoxy, N-ethyl dithiocarbamato)nitrido 99mTc] and 201TI images to estimate the utility of this compound in the detection of coronary artery disease (CAD). Methods: Twenty-five patients undergoing cardiac catheterization had stress-redistribution-reinjection 201TI SPECT imaging, stress-delayed (2, 4 and 6 hr postinjection) and rest-delayed (4 hr postinjection) TcN-NOET SPECT imaging. Results: Nineteen patients had coronary stenosis ≥50% and six were normal. Stress TcN-NOET and 201TI imaging were concordant for the presence of CAD in 22/25 patients (88%, κ = 0.76 ± 0.20). The overall sensitivity of TcN-NOET SPECT imaging was 74% (14/19 patients) and 68% (13/19 patients) for 201TI SPECT imaging. The specificity was 100% (6/6 patients) for both techniques. The overall agreement of TcN-NOET and 201TI for the presence of disease in individual coronary arteries was 96% (72/75 arteries, κ = 0.92 ± 0.16). Segmental analysis of stress images showed a concordance in 2...I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
