Single crystal X-ray structures of 4-phenyl sulfonyl 2-azetidinone 1, a 1:2 conglomerate of the corresponding 3-methyl (trans) and 3,3-dimethyl derivatives 2A and 2B/2C respectively and 3-acetoxymethyl 1,4-diphenyl 2-azetidinone 3 revealed interesting variation in crystal packing dictated by H-bonding and hydrophobic interactions which may be responsible for molecular recognition in β-lactams.
Molecular Recognition in Beta-lactams: the crystal packing in 4-sulfonyl Beta-lactams
BERTOLASI, Valerio;
2004
Abstract
Single crystal X-ray structures of 4-phenyl sulfonyl 2-azetidinone 1, a 1:2 conglomerate of the corresponding 3-methyl (trans) and 3,3-dimethyl derivatives 2A and 2B/2C respectively and 3-acetoxymethyl 1,4-diphenyl 2-azetidinone 3 revealed interesting variation in crystal packing dictated by H-bonding and hydrophobic interactions which may be responsible for molecular recognition in β-lactams.File in questo prodotto:
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