TESTA, Maria Francesca
TESTA, Maria Francesca
Dipartimento di Scienze della vita e biotecnologie
A factor X variant with engineered activation peptide as innovative by-passing agent for haemophilia
file con accesso da definire2022 Tonetto, E.; Tarantino, R.; Testa, M. F.; Peretto, L.; Bernardi, F.; Pinotti, M.; Branchini, A.
A novel tailored correction approach for recurrent hemophilia-causing nonsense mutations through AntiCodon-Engineered suppressor tRNAs
file con accesso da definire2023 Testa, Maria Francesca; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
An advanced method for the small-scale production of high-quality minicircle DNA
2021 Mitdank, Hardy; Sama, Simko; Tröger, Meike; Testa, Maria Francesca; Ferrarese, Mattia; Balestra, Dario; Pinotti, Mirko; Weng, Alexander
An engineered factor X variant as a novel by-passing agent for hemophilia
file con accesso da definire2022 Tonetto, Elena; Testa, Maria Francesca; Tarantino, Rebecca; Peretto, Laura; Pinotti, Mirko; Branchini, Alessio
An integrated multi-tool analysis contributes elements to interpreting unclassified factor IX missense variants associated with haemophilia B
file con accesso da definire2024 Sacco, Monica; Testa, Maria Francesca; Ferretti, Antonietta; Basso, Maria; Lancellotti, Stefano; Tardugno, Maira; Di Gennaro, Leonardo; Concolino, Paola; Minucci, Angelo; Spoliti, Claudia; Branchini, Alessio; De Cristofaro, Raimondo
Base and Prime Editors as new correction approaches for recurrent Hemophilia A Nonsense Mutations
file con accesso da definire2024 Testa, M.; Bernardi, F.; Branchini, A.; Pinotti, M.; Balestra, D.
Comparative Analysis Of Residual Factor VIII Expression from Recurrent F8 Nonsense Mutations Indicates that Localization in the B- domain Favours Readthrough- mediated Protein Output
2021 Testa, Maria Francesca; Lombardi, Silvia; Ferrarese, Mattia; Radossi, Paolo; Belvini, Donata; Castaman, Giancarlo; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
Design of an engineered coagulation factor X as a novel by-passing agent for hemophilia
file con accesso da definire2023 Tarantino, Rebecca; Tonetto, Elena; Testa, Maria Francesca; Pinotti, Mirko; Branchini, Alessio
Detection of Residual Factor VIII Levels Reveals the Occurrence of Readthrough Over the Majority of F8 Nonsense Mutations
2020 Testa, Maria Francesca; Lombardi, Silvia; Ferrarese, Mattia; Pinotti, Mirko; Castaman, Giancarlo; Radossi, Paolo; Belvini, Donata; Bernardi, Francesco; Branchini, Alessio
Engineered suppressor tRNAs as a novel correction approach for recurrent hemophilia A-causing nonsense mutations
file con accesso da definire2022 Testa, Maria Francesca; Lueck, John D.; Di Fiore, A.; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
Engineered tRNAs as a novel tailored correction approach to restore protein biosynthesis and function from hemophilia-causing nonsense mutations
file con accesso da definire2023 Testa, Maria Francesca; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
Exploring spontaneous readthrough over recurrent F8 nonsense mutations: potential correlation with inhibitor risk?
2019 Lombardi, Silvia; Testa, Maria Francesca; Pinotti, Mirko; Castman, Giancarlo; Radossi, Paolo; Bernardi, Francesco; Branchini, Alessio
Molecular insights into determinants of translational readthrough and implications for nonsense suppression approaches
2020 Lombardi, S.; Testa, M. F.; Pinotti, M.; Branchini, A.
Reverting highly frequent f8 nonsense mutations: base and prime editing approach for hemophilia A
file con accesso da definire2024 Testa, M. F.; Bernardi, F.; Branchini, A.; Pinotti, M.; Balestra, D.
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B
2018 Ferrarese, Mattia; Testa, Maria Francesca; Balestra, Dario; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B
2018 Ferrarese, Mattia; Testa, Maria Francesca; Balestra, Dario; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio
Spontaneous readthrough over recurrent F8 nonsense mutations is associated with residual factor VIII levels: implications for inhibitor risk?
2020 Testa, Maria Francesca; Lombardi, Silvia; Ferrarese, Mattia; Pinotti, Mirko; Castaman, Giancarlo; Radossi, Paolo; Belvini, Donata; Bernardi, Francesco; Branchini, Alessio
Tailored collagen binding confers distinct functional properties to engineered factor IX fusion proteins in hemophilia B mouse model
file con accesso da definire2024 Testa, M. F.; Aaen, K. H.; Nilsen, J.; Tarantino, R.; Canepari, C.; Cantore, A.; Bernardi, F.; Pinotti, M.; Andersen, J. T.; Branchini, A.
The heterozygous p.R854Q variant is responsible for the conformational changes in the D’D3 domain of the von Willebrand Factor, by weakening its interaction with factor VIII: in-silico analysis
file con accesso da definire2024 Tardugno, M.; Sacco, M.; Lancellotti, S.; Ferretti, A.; Basso, M.; Concolino, P.; Minnucci, A.; Testa, M. F.; Branchini, A.; De Cristofaro, R.
The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms
2022 Sacco, Monica; Lancellotti, Stefano; Branchini, Alessio; Tardugno, Maira; Testa, Maria Francesca; Lunghi, Barbara; Bernardi, Francesco; Pinotti, Mirko; Giusti, Betti; Castaman, Giancarlo; De Cristofaro, Raimondo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A factor X variant with engineered activation peptide as innovative by-passing agent for haemophilia | 2022 | Tonetto, E.; Tarantino, R.; Testa, M. F.; Peretto, L.; Bernardi, F.; Pinotti, M.; Branchini, A. | file con accesso da definire |
| A novel tailored correction approach for recurrent hemophilia-causing nonsense mutations through AntiCodon-Engineered suppressor tRNAs | 2023 | Testa, Maria Francesca; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio | file con accesso da definire |
| An advanced method for the small-scale production of high-quality minicircle DNA | 2021 | Mitdank, Hardy; Sama, Simko; Tröger, Meike; Testa, Maria Francesca; Ferrarese, Mattia; Balestra, ...Dario; Pinotti, Mirko; Weng, Alexander | |
| An engineered factor X variant as a novel by-passing agent for hemophilia | 2022 | Tonetto, Elena; Testa, Maria Francesca; Tarantino, Rebecca; Peretto, Laura; Pinotti, Mirko; Branc...hini, Alessio | file con accesso da definire |
| An integrated multi-tool analysis contributes elements to interpreting unclassified factor IX missense variants associated with haemophilia B | 2024 | Sacco, Monica; Testa, Maria Francesca; Ferretti, Antonietta; Basso, Maria; Lancellotti, Stefano; ...Tardugno, Maira; Di Gennaro, Leonardo; Concolino, Paola; Minucci, Angelo; Spoliti, Claudia; Branchini, Alessio; De Cristofaro, Raimondo | file con accesso da definire |
| Base and Prime Editors as new correction approaches for recurrent Hemophilia A Nonsense Mutations | 2024 | Testa, M.; Bernardi, F.; Branchini, A.; Pinotti, M.; Balestra, D. | file con accesso da definire |
| Comparative Analysis Of Residual Factor VIII Expression from Recurrent F8 Nonsense Mutations Indicates that Localization in the B- domain Favours Readthrough- mediated Protein Output | 2021 | Testa, Maria Francesca; Lombardi, Silvia; Ferrarese, Mattia; Radossi, Paolo; Belvini, Donata; Cas...taman, Giancarlo; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio | |
| Design of an engineered coagulation factor X as a novel by-passing agent for hemophilia | 2023 | Tarantino, Rebecca; Tonetto, Elena; Testa, Maria Francesca; Pinotti, Mirko; Branchini, Alessio | file con accesso da definire |
| Detection of Residual Factor VIII Levels Reveals the Occurrence of Readthrough Over the Majority of F8 Nonsense Mutations | 2020 | Testa, Maria Francesca; Lombardi, Silvia; Ferrarese, Mattia; Pinotti, Mirko; Castaman, Giancarlo;... Radossi, Paolo; Belvini, Donata; Bernardi, Francesco; Branchini, Alessio | |
| Engineered suppressor tRNAs as a novel correction approach for recurrent hemophilia A-causing nonsense mutations | 2022 | Testa, Maria Francesca; Lueck, John D.; Di Fiore, A.; Bernardi, Francesco; Pinotti, Mirko; Branch...ini, Alessio | file con accesso da definire |
| Engineered tRNAs as a novel tailored correction approach to restore protein biosynthesis and function from hemophilia-causing nonsense mutations | 2023 | Testa, Maria Francesca; Bernardi, Francesco; Pinotti, Mirko; Branchini, Alessio | file con accesso da definire |
| Exploring spontaneous readthrough over recurrent F8 nonsense mutations: potential correlation with inhibitor risk? | 2019 | Lombardi, Silvia; Testa, Maria Francesca; Pinotti, Mirko; Castman, Giancarlo; Radossi, Paolo; Ber...nardi, Francesco; Branchini, Alessio | |
| Molecular insights into determinants of translational readthrough and implications for nonsense suppression approaches | 2020 | Lombardi, S.; Testa, M. F.; Pinotti, M.; Branchini, A. | |
| Reverting highly frequent f8 nonsense mutations: base and prime editing approach for hemophilia A | 2024 | Testa, M. F.; Bernardi, F.; Branchini, A.; Pinotti, M.; Balestra, D. | file con accesso da definire |
| Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B | 2018 | Ferrarese, Mattia; Testa, Maria Francesca; Balestra, Dario; Bernardi, Francesco; Pinotti, Mirko; ...Branchini, Alessio | |
| Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B | 2018 | Ferrarese, Mattia; Testa, Maria Francesca; Balestra, Dario; Bernardi, Francesco; Pinotti, Mirko; ...Branchini, Alessio | |
| Spontaneous readthrough over recurrent F8 nonsense mutations is associated with residual factor VIII levels: implications for inhibitor risk? | 2020 | Testa, Maria Francesca; Lombardi, Silvia; Ferrarese, Mattia; Pinotti, Mirko; Castaman, Giancarlo;... Radossi, Paolo; Belvini, Donata; Bernardi, Francesco; Branchini, Alessio | |
| Tailored collagen binding confers distinct functional properties to engineered factor IX fusion proteins in hemophilia B mouse model | 2024 | Testa, M. F.; Aaen, K. H.; Nilsen, J.; Tarantino, R.; Canepari, C.; Cantore, A.; Bernardi, F.; Pi...notti, M.; Andersen, J. T.; Branchini, A. | file con accesso da definire |
| The heterozygous p.R854Q variant is responsible for the conformational changes in the D’D3 domain of the von Willebrand Factor, by weakening its interaction with factor VIII: in-silico analysis | 2024 | Tardugno, M.; Sacco, M.; Lancellotti, S.; Ferretti, A.; Basso, M.; Concolino, P.; Minnucci, A.; T...esta, M. F.; Branchini, A.; De Cristofaro, R. | file con accesso da definire |
| The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms | 2022 | Sacco, Monica; Lancellotti, Stefano; Branchini, Alessio; Tardugno, Maira; Testa, Maria Francesca;... Lunghi, Barbara; Bernardi, Francesco; Pinotti, Mirko; Giusti, Betti; Castaman, Giancarlo; De Cristofaro, Raimondo |