SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

BALESTRA, Dario
 Distribuzione geografica
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Continente #
NA - Nord America 6.162
EU - Europa 5.976
AS - Asia 3.742
SA - Sud America 513
Continente sconosciuto - Info sul continente non disponibili 215
AF - Africa 113
OC - Oceania 5
Totale 16.726
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Nazione #
US - Stati Uniti d'America 5.971
FI - Finlandia 3.885
SG - Singapore 1.324
CN - Cina 889
IT - Italia 563
VN - Vietnam 443
DE - Germania 425
BR - Brasile 385
PL - Polonia 327
HK - Hong Kong 279
GB - Regno Unito 179
TR - Turchia 155
BD - Bangladesh 151
UA - Ucraina 149
FR - Francia 117
JP - Giappone 110
CA - Canada 103
IN - India 93
ID - Indonesia 88
SE - Svezia 75
RU - Federazione Russa 69
MX - Messico 60
AR - Argentina 53
ZA - Sudafrica 49
BE - Belgio 35
ES - Italia 31
IQ - Iraq 31
NL - Olanda 25
EC - Ecuador 23
PK - Pakistan 21
MY - Malesia 20
CO - Colombia 17
RO - Romania 15
CZ - Repubblica Ceca 14
KE - Kenya 14
KR - Corea 14
SA - Arabia Saudita 13
LT - Lituania 12
UZ - Uzbekistan 12
IR - Iran 11
AT - Austria 10
CL - Cile 10
DZ - Algeria 10
JM - Giamaica 10
JO - Giordania 10
CH - Svizzera 9
MA - Marocco 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
PH - Filippine 8
TW - Taiwan 8
VE - Venezuela 8
CR - Costa Rica 7
NP - Nepal 7
PE - Perù 7
AZ - Azerbaigian 6
IL - Israele 6
AU - Australia 5
KG - Kirghizistan 5
NO - Norvegia 5
PT - Portogallo 5
AL - Albania 4
BG - Bulgaria 4
EG - Egitto 4
KZ - Kazakistan 4
TH - Thailandia 4
GE - Georgia 3
GR - Grecia 3
IE - Irlanda 3
LB - Libano 3
NG - Nigeria 3
OM - Oman 3
PY - Paraguay 3
UY - Uruguay 3
BH - Bahrain 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GA - Gabon 2
GF - Guiana Francese 2
HR - Croazia 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NI - Nicaragua 2
RS - Serbia 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
XK - ???statistics.table.value.countryCode.XK??? 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
BB - Barbados 1
BJ - Benin 1
BW - Botswana 1
CG - Congo 1
CI - Costa d'Avorio 1
DK - Danimarca 1
EU - Europa 1
GH - Ghana 1
GI - Gibilterra 1
Totale 16.497
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Città #
Helsinki 3.825
Singapore 797
Ashburn 697
San Jose 549
Fairfield 385
Beijing 325
Woodbridge 324
Warsaw 320
Santa Clara 313
Chandler 309
Hong Kong 265
Council Bluffs 250
Houston 231
Ann Arbor 218
Ferrara 194
Munich 169
Dallas 165
Seattle 155
Ho Chi Minh City 154
Jacksonville 145
Wilmington 134
Cambridge 127
Los Angeles 124
New York 124
Hanoi 97
Tokyo 96
Izmir 81
Jakarta 68
Milan 67
Bremen 64
Princeton 64
Nanjing 63
Lauterbourg 56
Boardman 46
São Paulo 41
Toronto 41
Orem 40
Shanghai 40
Rome 38
Mexico City 37
Brussels 33
Atlanta 32
London 32
Dearborn 31
Montreal 29
Brooklyn 26
Frankfurt am Main 26
Tianjin 25
Dong Ket 24
The Dalles 23
Chennai 22
Johannesburg 22
Phoenix 21
San Diego 21
Redwood City 20
Nanchang 19
Chicago 18
Moscow 18
Poplar 18
Buffalo 17
Da Nang 17
Denver 17
Rio de Janeiro 17
Stockholm 17
Turku 17
Bologna 16
Shenyang 16
Baghdad 15
Manchester 15
Changsha 14
Falkenstein 13
Mountain View 13
Nuremberg 13
Falls Church 12
Tashkent 12
Jiaxing 11
Kuala Lumpur 11
Mumbai 11
Nairobi 11
San Mateo 11
Hebei 10
Kunming 10
Norwalk 10
Paris 10
San Francisco 10
Shenzhen 10
Ankara 9
Biên Hòa 9
Brno 9
Florence 9
Guangzhou 9
Haiphong 9
Newark 9
Amman 8
Barcelona 8
Boston 8
Curitiba 8
Fairford 8
Lahore 8
Lappeenranta 8
Totale 12.173
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Nome #
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 2.055
A fixed mutation in the respiratory complex I impairs mitochondrial bioenergetics in the endangered Apennine brown bear 1.925
C6orf10 low-frequency and rare variants in italian multiple sclerosis patients 365
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 309
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 303
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 301
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 284
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 265
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 256
Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies 255
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 254
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 243
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 240
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 235
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 225
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 224
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 221
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 216
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 209
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 207
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 205
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 188
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 187
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 187
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 186
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 183
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 182
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 182
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 181
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 177
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 176
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 175
Rescue of coagulation factor VII function by the U1+5A snRNA 172
Molecular genetics and biology of congenital hemorrhagic diseases 170
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 168
RNA-based therapeutic approaches for blood coagulation factor deficiencies caused by a splicing mutations 163
The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies 159
Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function 158
Counteracting the Common Shwachman-Diamond Syndrome-Causing SBDS c.258+2T>C Mutation by RNA Therapeutics and Base/Prime Editing 156
An advanced method for the small-scale production of high-quality minicircle DNA 156
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies 153
Contribution of asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms to full-length FVIII concentrate pharmacokinetics 150
The Asialoglycoprotein Receptor Minor Subunit Gene Contributes to Pharmacokinetics of Factor VIII Concentrates in Hemophilia A 148
Molecular mechanisms and determinants of innovative correction approaches in coagulation factor deficiencies 144
Exon-Specific U1snRNA-Mediated Rescue of Splicing and Missense Changes in Hemophilia A 141
Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy 139
Rescue of coagulation factor VII mRNA processing and protein function by engineered U1+5A snRNA 138
MOLECULAR MECHANISMS AND THERAPEUTIC APROACHES FOR RESTORATION OF mRNA TRANSCRIPTION, MATURATION AND TRANSLATION IN INHERITED COAGULATION FACTOR DEFICIENCIES 136
“Compensatory” aberrant splicing supports residual expression levels in severe coagulation factor VII deficiency 134
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation Factor VII expression in mouse models 127
Prediction of inhibitor risk in haemophilia A using machine learning 124
Deep molecular mechanisms of F8 exon 19 variants and translational approaches in Hemophilia A 122
Base and Prime editing of DNA as a new therapeutic option for Hemophilia A 119
RNA−based therapeutic approaches for blood coagulation factor deficiencies caused by splicing mutations 119
Whole-Exome Sequencing in a Family with an Unexplained Tendency for Venous Thromboembolism: Multicomponent Prediction of Low-Frequency Variant Deleteriousness and of Individual Protein Interaction 109
La terapia genica nelle Malattie emorragiche e trombotiche 109
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation factor VII expression in mouse models 108
Restoration of coagulation factor IX function impaired by different splicing mutations by a unique exon-specific U1 small nuclear RNA (snRNA) 107
An engineered U1 small nuclear RNA rescues splicing-defective coagulationF7gene expression in mice 107
F8 splicing-swithcing molecules for tailored hemophilia A therapies 106
The asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms influence several parameters of full-length FVIII concentrate pharmacokinetics 104
Rescue of multiple Haemophilia A-causing mutations by a single ExSpeU1: the importance of the genomic context 103
Rescue of a FVIII splicing variant with engineered U1snRNAs 98
New Genome Editing Approaches: Base And Prime Editing To Revert Hemophilia A-Causing Point Mutations 93
Elucidation of aberrant SBDS splicing mechanisms to design RNA-therapeutics for Shwachman-Diamond Syndrome 93
Coexisting With Humans: Genomic and Behavioral Consequences in a Small and Isolated Bear Population 91
Base and Prime Editors as new correction approaches for recurrent Hemophilia A Nonsense Mutations 91
Rescue of a panel of Hemophilia A-causing 5’ss splicing mutations by unique Exon-specific U1snRNA variants 90
A 5’ SPLICE-SITE MUTATION CAUSING MUCOLIPIDOSIS TYPE III CAN BE EFFICIENTLY RESCUED BY U1 SNRNA-BASED THERAPY 88
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Rescue of an F8 splicing variant (c.1752+5 G>C) with engineered U1snRNAs 82
Rescue of a panel of splicing mutations causing hemophilia A by engineered U1snRNAs 81
Rescue of a hemophilia A-causing FVIII splicing variant via engineered U1SNRNAS 80
Reverting highly frequent f8 nonsense mutations: base and prime editing approach for hemophilia A 80
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Novel Genetic Classification of Inhibitor Risk for F8 Nonsense Mutations Based on Immunogenic Profiling of Ribosomal Readthrough in EAHAD Database 71
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DNA base editing corrects common hemophilia A mutations and restores factor VIII expression in in vitro and ex vivo models 68
RNA-Based therapeutics for OTC deficiency 64
Not Just Loss-of-Function Variations: Identification of a Hypermorphic Variant in a Patient With a CDKL5 Missense Substitution 55
RESCUE OF A PANEL OF SPLICING MUTATIONS CAUSING HEMOPHILIA A BY ENGINEERED U1-SNRNAS 54
La terapia genica nelle terapie emorragiche e trombotiche 53
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Prime editing of the common Familial Dysautonomia-causing c.2204+6T>C splicing mutation 48
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Molecular mechanisms and therapeutic strategies for the recurrent F9 (c.520 + 13 A > G) variant in hemophilia B 16
Totale 16.726
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Categoria #
all - tutte 62.938
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 923
Totale 63.861
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022549 0 75 10 16 25 28 36 20 25 61 32 221
2022/2023734 80 70 20 100 138 81 52 51 76 9 40 17
2023/2024404 18 51 20 22 26 58 21 26 9 19 13 121
2024/20252.024 50 39 177 68 222 249 107 78 346 208 259 221
2025/20269.371 518 214 437 720 754 386 691 357 4.204 611 317 162
2026/2027485 172 313 0 0 0 0 0 0 0 0 0 0
Totale 16.726