SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

BALESTRA, Dario
 Distribuzione geografica
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Continente #
NA - Nord America 2.977
EU - Europa 1.087
AS - Asia 643
OC - Oceania 2
AF - Africa 1
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 4.712
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Nazione #
US - Stati Uniti d'America 2.969
CN - Cina 321
IT - Italia 298
PL - Polonia 286
DE - Germania 145
TR - Turchia 127
UA - Ucraina 124
SG - Singapore 81
GB - Regno Unito 74
SE - Svezia 44
FI - Finlandia 34
ID - Indonesia 31
BE - Belgio 29
VN - Vietnam 24
HK - Hong Kong 14
RO - Romania 12
CZ - Repubblica Ceca 11
FR - Francia 10
KR - Corea 10
IR - Iran 9
CA - Canada 8
IN - India 8
JP - Giappone 6
NL - Olanda 5
RU - Federazione Russa 5
TW - Taiwan 5
NO - Norvegia 3
AU - Australia 2
ES - Italia 2
GE - Georgia 2
TH - Thailandia 2
AT - Austria 1
BG - Bulgaria 1
BR - Brasile 1
CH - Svizzera 1
DK - Danimarca 1
EU - Europa 1
IL - Israele 1
MY - Malesia 1
PK - Pakistan 1
PT - Portogallo 1
ZA - Sudafrica 1
Totale 4.712
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Città #
Fairfield 385
Woodbridge 324
Chandler 309
Warsaw 286
Ann Arbor 218
Houston 215
Ashburn 192
Seattle 151
Jacksonville 144
Ferrara 140
Wilmington 133
Cambridge 126
Izmir 80
Beijing 76
Bremen 64
Princeton 64
Nanjing 63
Singapore 47
New York 37
Milan 36
Boardman 34
Shanghai 33
Dearborn 31
Jakarta 30
Brussels 27
Dong Ket 24
San Diego 21
Redwood City 20
Nanchang 19
Shenyang 16
Tianjin 15
Mountain View 13
Falls Church 12
Los Angeles 12
Jiaxing 11
San Mateo 11
Changsha 10
Hebei 10
Kunming 10
Bologna 9
Brno 9
Helsinki 8
Hong Kong 8
London 8
Norwalk 8
Rome 8
Toronto 8
Auburn Hills 7
Des Moines 7
Andover 6
Florence 6
Guangzhou 6
Jinan 6
Leawood 6
Ningbo 6
Augusta 5
Haikou 5
Munich 5
Cagliari 4
Castelcovati 4
Chicago 4
Ferrara di Monte Baldo 4
Hangzhou 4
Monmouth Junction 4
Moscow 4
Orange 4
Paris 4
Redmond 4
Sala 4
Shenzhen 4
Zhengzhou 4
Ardabil 3
Atlanta 3
Ithaca 3
Oslo 3
Piemonte 3
Santa Clara 3
Trieste 3
Washington 3
Wuhan 3
Alexandria 2
Bagnacavallo 2
Bari 2
Belvedere Spinello 2
Cheltenham 2
Gloucester 2
Hounslow 2
Indiana 2
Nutley 2
Olomouc 2
Reggio Emilia 2
Sabz 2
Seocho-gu 2
Seodaemun-gu 2
Seongbuk-gu 2
Tabriz 2
Taipei 2
Taizhou 2
Tappahannock 2
Venice 2
Totale 3.699
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Nome #
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 179
C6orf10 low-frequency and rare variants in italian multiple sclerosis patients 179
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 170
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 166
Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies 166
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 145
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 141
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 120
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 116
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 116
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 113
Rescue of coagulation factor VII function by the U1+5A snRNA 107
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 107
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 100
The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies 100
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 98
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 96
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 95
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 93
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 89
null 87
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 87
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 84
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 82
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 80
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Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy 75
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Molecular genetics and biology of congenital hemorrhagic diseases 72
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Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 70
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 70
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 69
Molecular mechanisms and determinants of innovative correction approaches in coagulation factor deficiencies 68
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 67
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 64
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 60
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 59
MOLECULAR MECHANISMS AND THERAPEUTIC APROACHES FOR RESTORATION OF mRNA TRANSCRIPTION, MATURATION AND TRANSLATION IN INHERITED COAGULATION FACTOR DEFICIENCIES 55
null 51
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 51
Exon-Specific U1snRNA-Mediated Rescue of Splicing and Missense Changes in Hemophilia A 50
Restoration of coagulation factor IX function impaired by different splicing mutations by a unique exon-specific U1 small nuclear RNA (snRNA). 45
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 45
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Contribution of asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms to full-length FVIII concentrate pharmacokinetics 41
The Asialoglycoprotein Receptor Minor Subunit Gene Contributes to Pharmacokinetics of Factor VIII Concentrates in Hemophilia A 41
RNA-based therapeutic approaches for blood coagulation factor deficiencies caused by a splicing mutations 40
Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function 39
The asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms influence several parameters of full-length FVIII concentrate pharmacokinetics 37
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies 33
Elucidation of aberrant SBDS splicing mechanisms to design RNA-therapeutics for Shwachman-Diamond Syndrome 32
La terapia genica nelle Malattie emorragiche e trombotiche 31
An advanced method for the small-scale production of high-quality minicircle DNA 31
Rescue of coagulation factor VII mRNA processing and protein function by engineered U1+5A snRNA 30
F8 splicing-swithcing molecules for tailored hemophilia A therapies 29
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 29
RNA−based therapeutic approaches for blood coagulation factor deficiencies caused by splicing mutations 28
Deep molecular mechanisms of F8 exon 19 variants and translational approaches in Hemophilia A 27
“Compensatory” aberrant splicing supports residual expression levels in severe coagulation factor VII deficiency 24
Rescue of multiple Haemophilia A-causing mutations by a single ExSpeU1: the importance of the genomic context 22
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation Factor VII expression in mouse models 21
RNA-Based therapeutics for OTC deficiency 20
Counteracting the Common Shwachman-Diamond Syndrome-Causing SBDS c.258+2T>C Mutation by RNA Therapeutics and Base/Prime Editing 17
Base and Prime editing of DNA as a new therapeutic option for Hemophilia A 16
An engineered U1 small nuclear RNA rescues splicing-defective coagulationF7gene expression in mice 16
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation factor VII expression in mouse models 14
Not Just Loss-of-Function Variations: Identification of a Hypermorphic Variant in a Patient With a CDKL5 Missense Substitution 12
Rescue of a FVIII splicing variant with engineered U1snRNAs 9
Rescue of a hemophilia A-causing FVIII splicing variant via engineered U1SNRNAS 6
New Genome Editing Approaches: Base And Prime Editing To Revert Hemophilia A-Causing Point Mutations 6
Whole-Exome Sequencing in a Family with an Unexplained Tendency for Venous Thromboembolism: Multicomponent Prediction of Low-Frequency Variant Deleteriousness and of Individual Protein Interaction 6
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Totale 4.887
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Categoria #
all - tutte 22.560
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 304
Totale 22.864
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.036 150 49 58 130 87 118 100 82 93 74 66 29
2020/2021986 74 40 49 96 40 79 128 103 52 166 112 47
2021/2022603 54 75 10 16 25 28 36 20 25 61 32 221
2022/2023734 80 70 20 100 138 81 52 51 76 9 40 17
2023/2024404 18 51 20 22 26 58 21 26 9 19 13 121
2024/202541 41 0 0 0 0 0 0 0 0 0 0 0
Totale 4.887