SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

BALESTRA, Dario
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 3.350
EU - Europa 1.240
AS - Asia 885
AF - Africa 3
OC - Oceania 2
SA - Sud America 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.483
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 3.332
CN - Cina 356
IT - Italia 336
PL - Polonia 286
SG - Singapore 242
DE - Germania 194
TR - Turchia 128
UA - Ucraina 124
GB - Regno Unito 80
FI - Finlandia 78
ID - Indonesia 63
SE - Svezia 44
BE - Belgio 34
VN - Vietnam 24
CA - Canada 18
HK - Hong Kong 16
IN - India 12
RO - Romania 12
CZ - Repubblica Ceca 11
FR - Francia 11
KR - Corea 10
IR - Iran 9
NL - Olanda 8
RU - Federazione Russa 7
JP - Giappone 6
TW - Taiwan 6
ES - Italia 3
NO - Norvegia 3
ZA - Sudafrica 3
AT - Austria 2
AU - Australia 2
CH - Svizzera 2
GE - Georgia 2
IL - Israele 2
KG - Kirghizistan 2
PK - Pakistan 2
TH - Thailandia 2
AZ - Azerbaigian 1
BG - Bulgaria 1
BR - Brasile 1
DK - Danimarca 1
EU - Europa 1
HR - Croazia 1
JO - Giordania 1
LT - Lituania 1
MY - Malesia 1
PE - Perù 1
PT - Portogallo 1
Totale 5.483
Salva come PNG Salva come JPEG
Città #
Fairfield 385
Woodbridge 324
Chandler 309
Warsaw 286
Santa Clara 265
Ann Arbor 218
Houston 215
Singapore 204
Ashburn 199
Ferrara 157
Seattle 151
Jacksonville 144
Wilmington 133
Cambridge 126
Izmir 80
Beijing 76
Bremen 64
Princeton 64
Nanjing 63
Jakarta 62
Helsinki 48
Milan 39
New York 38
Munich 35
Shanghai 35
Boardman 34
Brussels 32
Dearborn 31
Los Angeles 25
Dong Ket 24
San Diego 21
Redwood City 20
Nanchang 19
Shenyang 16
Toronto 16
Tianjin 15
Mountain View 13
Falls Church 12
London 12
Bologna 11
Jiaxing 11
San Mateo 11
Changsha 10
Hebei 10
Hong Kong 10
Kunming 10
Brno 9
Rome 9
Falkenstein 8
Norwalk 8
Auburn Hills 7
Des Moines 7
Frankfurt am Main 7
Andover 6
Florence 6
Guangzhou 6
Jinan 6
Leawood 6
Ningbo 6
Shenzhen 6
Augusta 5
Haikou 5
Zhengzhou 5
Bari 4
Cagliari 4
Castelcovati 4
Chicago 4
Ferrara di Monte Baldo 4
Hangzhou 4
Monmouth Junction 4
Moscow 4
Orange 4
Paris 4
Redmond 4
Sala 4
Ardabil 3
Atlanta 3
Espoo 3
Ithaca 3
Oslo 3
Piemonte 3
Trieste 3
Washington 3
Wuhan 3
Alexandria 2
Bagnacavallo 2
Barcelona 2
Bellville 2
Belvedere Spinello 2
Bengaluru 2
Bishkek 2
Cheltenham 2
Chengdu 2
Gloucester 2
Hounslow 2
Indiana 2
Islamabad 2
Lohmar 2
Lucknow 2
Nutley 2
Totale 4.302
Salva come PNG Salva come JPEG
Nome #
C6orf10 low-frequency and rare variants in italian multiple sclerosis patients 195
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 190
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 185
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 179
Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies 174
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 153
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 153
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 130
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 128
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 127
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 121
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 118
Rescue of coagulation factor VII function by the U1+5A snRNA 111
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 110
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 110
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 109
The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies 108
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 104
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 103
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 100
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 99
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 97
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 94
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 93
null 87
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 87
Molecular genetics and biology of congenital hemorrhagic diseases 83
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 81
Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy 81
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 81
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 80
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 79
null 79
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 78
null 77
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 74
null 73
Molecular mechanisms and determinants of innovative correction approaches in coagulation factor deficiencies 73
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 73
null 71
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 65
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 64
MOLECULAR MECHANISMS AND THERAPEUTIC APROACHES FOR RESTORATION OF mRNA TRANSCRIPTION, MATURATION AND TRANSLATION IN INHERITED COAGULATION FACTOR DEFICIENCIES 61
Exon-Specific U1snRNA-Mediated Rescue of Splicing and Missense Changes in Hemophilia A 61
RNA-based therapeutic approaches for blood coagulation factor deficiencies caused by a splicing mutations 53
Restoration of coagulation factor IX function impaired by different splicing mutations by a unique exon-specific U1 small nuclear RNA (snRNA). 52
Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function 52
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies 52
null 51
The Asialoglycoprotein Receptor Minor Subunit Gene Contributes to Pharmacokinetics of Factor VIII Concentrates in Hemophilia A 51
Contribution of asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms to full-length FVIII concentrate pharmacokinetics 49
An advanced method for the small-scale production of high-quality minicircle DNA 44
The asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms influence several parameters of full-length FVIII concentrate pharmacokinetics 43
null 42
Rescue of coagulation factor VII mRNA processing and protein function by engineered U1+5A snRNA 40
Elucidation of aberrant SBDS splicing mechanisms to design RNA-therapeutics for Shwachman-Diamond Syndrome 39
La terapia genica nelle Malattie emorragiche e trombotiche 37
Deep molecular mechanisms of F8 exon 19 variants and translational approaches in Hemophilia A 37
RNA−based therapeutic approaches for blood coagulation factor deficiencies caused by splicing mutations 36
Counteracting the Common Shwachman-Diamond Syndrome-Causing SBDS c.258+2T>C Mutation by RNA Therapeutics and Base/Prime Editing 35
F8 splicing-swithcing molecules for tailored hemophilia A therapies 35
“Compensatory” aberrant splicing supports residual expression levels in severe coagulation factor VII deficiency 34
Rescue of multiple Haemophilia A-causing mutations by a single ExSpeU1: the importance of the genomic context 30
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation Factor VII expression in mouse models 27
Base and Prime editing of DNA as a new therapeutic option for Hemophilia A 26
RNA-Based therapeutics for OTC deficiency 26
Rescue of a FVIII splicing variant with engineered U1snRNAs 25
Prediction of inhibitor risk in haemophilia A using machine learning 23
An engineered U1 small nuclear RNA rescues splicing-defective coagulationF7gene expression in mice 23
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation factor VII expression in mouse models 20
Whole-Exome Sequencing in a Family with an Unexplained Tendency for Venous Thromboembolism: Multicomponent Prediction of Low-Frequency Variant Deleteriousness and of Individual Protein Interaction 19
Rescue of a hemophilia A-causing FVIII splicing variant via engineered U1SNRNAS 18
New Genome Editing Approaches: Base And Prime Editing To Revert Hemophilia A-Causing Point Mutations 18
Not Just Loss-of-Function Variations: Identification of a Hypermorphic Variant in a Patient With a CDKL5 Missense Substitution 17
La terapia genica nelle terapie emorragiche e trombotiche 7
Reverting highly frequent f8 nonsense mutations: base and prime editing approach for hemophilia A 2
Base and Prime Editors as new correction approaches for recurrent Hemophilia A Nonsense Mutations 2
Rescue of a panel of splicing mutations causing hemophilia A by engineered U1snRNAs 2
Totale 5.666
Salva come PNG Salva come JPEG
Categoria #
all - tutte 30.669
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 443
Totale 31.112
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020444 0 0 0 0 0 0 100 82 93 74 66 29
2020/2021986 74 40 49 96 40 79 128 103 52 166 112 47
2021/2022603 54 75 10 16 25 28 36 20 25 61 32 221
2022/2023734 80 70 20 100 138 81 52 51 76 9 40 17
2023/2024404 18 51 20 22 26 58 21 26 9 19 13 121
2024/2025820 50 39 177 68 222 249 15 0 0 0 0 0
Totale 5.666