SFERA Archivio dei prodotti della Ricerca dell'Università di Ferrara

BALESTRA, Dario
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 4.536
AS - Asia 2.608
EU - Europa 1.831
SA - Sud America 397
AF - Africa 54
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 2
Totale 9.431
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 4.417
SG - Singapore 1.044
CN - Cina 719
DE - Germania 403
IT - Italia 383
BR - Brasile 329
PL - Polonia 320
HK - Hong Kong 245
VN - Vietnam 174
GB - Regno Unito 145
UA - Ucraina 145
TR - Turchia 141
FI - Finlandia 134
ID - Indonesia 81
RU - Federazione Russa 66
CA - Canada 61
SE - Svezia 57
MX - Messico 52
IN - India 49
FR - Francia 48
AR - Argentina 35
BE - Belgio 34
ZA - Sudafrica 33
JP - Giappone 32
BD - Bangladesh 23
NL - Olanda 19
ES - Italia 16
RO - Romania 14
CZ - Repubblica Ceca 13
EC - Ecuador 13
KR - Corea 12
IR - Iran 11
IQ - Iraq 10
AT - Austria 8
LT - Lituania 8
MY - Malesia 8
CO - Colombia 7
TW - Taiwan 7
UZ - Uzbekistan 7
MA - Marocco 6
AE - Emirati Arabi Uniti 5
IL - Israele 5
PE - Perù 5
PK - Pakistan 5
AZ - Azerbaigian 4
KE - Kenya 4
KG - Kirghizistan 4
CH - Svizzera 3
DZ - Algeria 3
JO - Giordania 3
NO - Norvegia 3
OM - Oman 3
PT - Portogallo 3
TN - Tunisia 3
UY - Uruguay 3
AU - Australia 2
CR - Costa Rica 2
GE - Georgia 2
LA - Repubblica Popolare Democratica del Laos 2
NP - Nepal 2
SA - Arabia Saudita 2
TH - Thailandia 2
VE - Venezuela 2
XK - ???statistics.table.value.countryCode.XK??? 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
BG - Bulgaria 1
BH - Bahrain 1
BO - Bolivia 1
BW - Botswana 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EG - Egitto 1
EU - Europa 1
GA - Gabon 1
GF - Guiana Francese 1
GH - Ghana 1
GI - Gibilterra 1
GR - Grecia 1
HN - Honduras 1
HR - Croazia 1
IE - Irlanda 1
JM - Giamaica 1
KW - Kuwait 1
LB - Libano 1
LU - Lussemburgo 1
MD - Moldavia 1
NG - Nigeria 1
NI - Nicaragua 1
PH - Filippine 1
PY - Paraguay 1
TJ - Tagikistan 1
Totale 9.431
Salva come PNG Salva come JPEG
Città #
Singapore 568
Ashburn 485
Fairfield 385
Woodbridge 324
Warsaw 313
Chandler 309
Santa Clara 286
Beijing 279
Hong Kong 239
Houston 227
Ann Arbor 218
Ferrara 176
Munich 169
Seattle 154
Dallas 152
Jacksonville 145
Wilmington 134
Cambridge 126
Los Angeles 101
New York 87
Helsinki 81
Izmir 80
Jakarta 67
Bremen 64
Princeton 64
Nanjing 63
Ho Chi Minh City 61
Milan 43
Boardman 41
Shanghai 37
São Paulo 34
Brussels 32
Mexico City 32
Dearborn 31
Hanoi 28
Toronto 25
Dong Ket 24
Brooklyn 23
London 23
Tianjin 23
Atlanta 22
San Diego 21
Montreal 20
Redwood City 20
Frankfurt am Main 19
Nanchang 19
Tokyo 19
Moscow 18
Johannesburg 17
Turku 17
Chicago 16
Poplar 16
Shenyang 16
The Dalles 15
Chennai 14
Orem 14
Rio de Janeiro 14
Falkenstein 13
Mountain View 13
Stockholm 13
Bologna 12
Changsha 12
Denver 12
Falls Church 12
Nuremberg 12
Jiaxing 11
Manchester 11
San Mateo 11
Hebei 10
Kunming 10
Ankara 9
Brno 9
Rome 9
Fairford 8
Norwalk 8
Phoenix 8
Auburn Hills 7
Belo Horizonte 7
Biên Hòa 7
Boston 7
Buffalo 7
Campinas 7
Columbus 7
Des Moines 7
Dortmund 7
Kuala Lumpur 7
Tashkent 7
Zhengzhou 7
Andover 6
Council Bluffs 6
Florence 6
Fortaleza 6
Guangzhou 6
Hefei 6
Jinan 6
Leawood 6
Ningbo 6
San Francisco 6
San Jose 6
Shenzhen 6
Totale 6.409
Salva come PNG Salva come JPEG
Nome #
C6orf10 low-frequency and rare variants in italian multiple sclerosis patients 286
AN EXON-SPECIFIC U1 SMALL NUCLEAR RNA (snRNA) STRATEGY TO CORRECT SPLICING MUTATIONS ASSOCIATED TO HEMOPHILIA B 259
Regulation of a strong F9 cryptic 5'ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides 250
An exon-specific U1snRNA induces a robust factor IX activity in mice expressing multiple human FIX splicing mutants 243
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy 240
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function 210
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 207
Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies 202
Activation of a cryptic splice site in a potentially lethal coagulation defect accounts for a functional protein variant 200
U1snRNA-mediated rescue of mRNA processing in severe factor VII deficiency 198
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects 189
Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death 187
An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A 183
A unique exon specific U1snRNA rescues different haemophilia B - causing splicing-defective factor IX variants in mice 178
The chaperone-like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation 175
Correction of aberrant splicing causing haemophilia B through the combination of compensatory U1snRNAs and antisense oligonucleotides 160
Aberrant splicing reverts a potentially lethal coagulation deficiency caused by a +1g/t splicing mutation 154
The complete impairment of factor VII gene expression by the IVS6+1g/t mutation is compatible with a severe but not lethal bleeding disorder 154
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 153
Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B 150
A strategy with chaperone-like compounds to restore expression of factor IX variants affected by frequent missense mutations causing hemophilia B 149
Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs 148
A very rare simultaneous presence of a ring chromosome 13 and a splicing site mutation on Factor X gene 146
Rescue of coagulation factor VII function by the U1+5A snRNA 143
The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies 141
Next-generation sequencing and recombinant expression characterized aberrant splicing mechanisms and provided correction strategies in factor VII deficiency 141
Rescue of missense and splicing mutations in Haemophilia A by a unique Exon Specific U1snRNA 140
Non-conventional therapeutic strategies for inherited disorders oh hemostasis 138
The carboxyl-terminal region of human coagulation factor X as a novel naturally-occuring linker for fusion strategies 138
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction 135
The F7 p.Val22Ile missense mutation affects splicing and can be counteracted by a compensatory U1snRNA 134
Molecular genetics and biology of congenital hemorrhagic diseases 132
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I 130
An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency 130
The chaperone-like compound sodium phenylbutyrate improves intracellular trafficking, secretion and coagulant activity of factor IX impaired by the frequent p.R294Q mutation 127
Splicing Mutations Impairing CDKL5 Expression and Activity Can be Efficiently Rescued by U1snRNA-Based Therapy 124
RNA-based therapeutic approaches for blood coagulation factor deficiencies caused by a splicing mutations 119
Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function 119
Molecular mechanisms and determinants of innovative correction approaches in coagulation factor deficiencies 118
The Asialoglycoprotein Receptor Minor Subunit Gene Contributes to Pharmacokinetics of Factor VIII Concentrates in Hemophilia A 117
Exon-Specific U1snRNA-Mediated Rescue of Splicing and Missense Changes in Hemophilia A 115
Counteracting the Common Shwachman-Diamond Syndrome-Causing SBDS c.258+2T>C Mutation by RNA Therapeutics and Base/Prime Editing 112
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies 108
An advanced method for the small-scale production of high-quality minicircle DNA 104
Contribution of asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms to full-length FVIII concentrate pharmacokinetics 102
MOLECULAR MECHANISMS AND THERAPEUTIC APROACHES FOR RESTORATION OF mRNA TRANSCRIPTION, MATURATION AND TRANSLATION IN INHERITED COAGULATION FACTOR DEFICIENCIES 100
Rescue of coagulation factor VII mRNA processing and protein function by engineered U1+5A snRNA 99
RNA−based therapeutic approaches for blood coagulation factor deficiencies caused by splicing mutations 90
null 87
Restoration of coagulation factor IX function impaired by different splicing mutations by a unique exon-specific U1 small nuclear RNA (snRNA) 87
Deep molecular mechanisms of F8 exon 19 variants and translational approaches in Hemophilia A 87
Base and Prime editing of DNA as a new therapeutic option for Hemophilia A 83
null 79
Elucidation of aberrant SBDS splicing mechanisms to design RNA-therapeutics for Shwachman-Diamond Syndrome 78
null 77
The asialoglycoprotein receptor ASGR2 5’ UTR polymorphisms influence several parameters of full-length FVIII concentrate pharmacokinetics 75
“Compensatory” aberrant splicing supports residual expression levels in severe coagulation factor VII deficiency 74
An engineered U1 small nuclear RNA rescues splicing-defective coagulationF7gene expression in mice 74
La terapia genica nelle Malattie emorragiche e trombotiche 74
null 73
Prediction of inhibitor risk in haemophilia A using machine learning 72
F8 splicing-swithcing molecules for tailored hemophilia A therapies 72
Rescue of a FVIII splicing variant with engineered U1snRNAs 71
null 71
Whole-Exome Sequencing in a Family with an Unexplained Tendency for Venous Thromboembolism: Multicomponent Prediction of Low-Frequency Variant Deleteriousness and of Individual Protein Interaction 70
Rescue of multiple Haemophilia A-causing mutations by a single ExSpeU1: the importance of the genomic context 66
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation Factor VII expression in mouse models 65
Delivery of a modified U1 small nuclear RNA alleviates splicing-defective coagulation factor VII expression in mouse models 65
New Genome Editing Approaches: Base And Prime Editing To Revert Hemophilia A-Causing Point Mutations 59
Base and Prime Editors as new correction approaches for recurrent Hemophilia A Nonsense Mutations 59
Rescue of a hemophilia A-causing FVIII splicing variant via engineered U1SNRNAS 58
Reverting highly frequent f8 nonsense mutations: base and prime editing approach for hemophilia A 54
null 51
RNA-Based therapeutics for OTC deficiency 48
Rescue of a panel of splicing mutations causing hemophilia A by engineered U1snRNAs 45
Rescue of an F8 splicing variant (c.1752+5 G>C) with engineered U1snRNAs 44
Rescue of a panel of Hemophilia A-causing 5’ss splicing mutations by unique Exon-specific U1snRNA variants 43
null 42
A 5’ SPLICE-SITE MUTATION CAUSING MUCOLIPIDOSIS TYPE III CAN BE EFFICIENTLY RESCUED BY U1 SNRNA-BASED THERAPY 42
Not Just Loss-of-Function Variations: Identification of a Hypermorphic Variant in a Patient With a CDKL5 Missense Substitution 40
La terapia genica nelle terapie emorragiche e trombotiche 31
RESCUE OF A PANEL OF SPLICING MUTATIONS CAUSING HEMOPHILIA A BY ENGINEERED U1-SNRNAS 28
A fixed mutation in the respiratory complex I impairs mitochondrial bioenergetics in the endangered Apennine brown bear 3
DNA base editing corrects common hemophilia A mutations and restores factor VIII expression in in vitro and ex vivo models 1
Totale 9.625
Salva come PNG Salva come JPEG
Categoria #
all - tutte 47.524
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 738
Totale 48.262
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021687 0 0 0 0 0 79 128 103 52 166 112 47
2021/2022603 54 75 10 16 25 28 36 20 25 61 32 221
2022/2023734 80 70 20 100 138 81 52 51 76 9 40 17
2023/2024404 18 51 20 22 26 58 21 26 9 19 13 121
2024/20252.024 50 39 177 68 222 249 107 78 346 208 259 221
2025/20262.755 518 214 437 720 754 112 0 0 0 0 0 0
Totale 9.625