Resolvin D1 reduces the inflammatory response to rhinovirus infection in COPD bronchial epithelial cells

This in-vitro study showed that resolvin D1 reduced the pro-inflammatory response to rhinovirus infection in bronchial epithelial cells from COPD patients. Treatment with RvD1 significantly lowered IL-6 and IL-1β release without suppressing interferon production, viral load, or interferon-stimulated gene expression. These findings suggest that RvD1 can dampen airway inflammation while preserving antiviral immunity, supporting its potential role as a therapeutic strategy to aid recovery during COPD exacerbations.