Aqueous dispersions of biopolyesters have long been used in the drug delivery sector, typically in highly diluted formulations (1-5% or less) [1]. However, when prepared at higher concentrations, they offer new opportunities that were largely unexplored until recently. They can be used to prepare films and polymer coatings in a manner similar to vinyl polymer dispersions. Compared to these, they offer significant environmental advantages due to their biodegradability and inherent recyclability. In our research group, we have managed to obtain biopolyester dispersions with solid concentrations up to 40%, which are stable for at least six months [2-3]. These dispersions have been applied as coatings on paper, providing resistance to water and oil, while maintaining the biodegradability and recyclability of the paper [3]. The dispersions can also be simply used to prepare environmentally sustainable blends with water-soluble polymers, such as polyvinyl alcohol [4]. They can be mixed with easily dispersible fillers, such as graphene oxide (GO) to produce electrochemical sensor after grafitization of GO. Finally, they also facilitate the easy incorporation of thermolabile bioactive molecules, such as osteogenic peptides, which were successfully incorporated into PLA films and tested as substrates for stem cell growth and differentiation.
Aqueous Dispersions of Biopolyesters: Exploring New Frontiers and Applications
M. Calosi;A. D'Iorio;E. Buratti;V. Mazzanti;G. Ronconi;Elisa Mazzoni;Monica Bertoldo
2025
Abstract
Aqueous dispersions of biopolyesters have long been used in the drug delivery sector, typically in highly diluted formulations (1-5% or less) [1]. However, when prepared at higher concentrations, they offer new opportunities that were largely unexplored until recently. They can be used to prepare films and polymer coatings in a manner similar to vinyl polymer dispersions. Compared to these, they offer significant environmental advantages due to their biodegradability and inherent recyclability. In our research group, we have managed to obtain biopolyester dispersions with solid concentrations up to 40%, which are stable for at least six months [2-3]. These dispersions have been applied as coatings on paper, providing resistance to water and oil, while maintaining the biodegradability and recyclability of the paper [3]. The dispersions can also be simply used to prepare environmentally sustainable blends with water-soluble polymers, such as polyvinyl alcohol [4]. They can be mixed with easily dispersible fillers, such as graphene oxide (GO) to produce electrochemical sensor after grafitization of GO. Finally, they also facilitate the easy incorporation of thermolabile bioactive molecules, such as osteogenic peptides, which were successfully incorporated into PLA films and tested as substrates for stem cell growth and differentiation.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
