The production of Ga-68 via liquid target cyclotron system improves the on-demand availability of this attractive PET isotope to cyclotron centres, while producing higher quantities than currently available from commercial generators. We devised an improved purification method for cyclotron produced Ga-68 in a liquid target that enables radiolabeling of DOTA-TOC using standard conditions. An in vivo study comparing DOTA-TOC radiolabeled with either generator or liquid target produced Ga-68 was also conducted.
Peptide radiolabeling and in vivo imaging using Ga-68 directly produced in liquid targets
Martini, PInvestigation
;
2017
Abstract
The production of Ga-68 via liquid target cyclotron system improves the on-demand availability of this attractive PET isotope to cyclotron centres, while producing higher quantities than currently available from commercial generators. We devised an improved purification method for cyclotron produced Ga-68 in a liquid target that enables radiolabeling of DOTA-TOC using standard conditions. An in vivo study comparing DOTA-TOC radiolabeled with either generator or liquid target produced Ga-68 was also conducted.File in questo prodotto:
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