Xenotransplantation, the transplantation of cells, tissues, or organs between different species, has the potential to overcome the current shortage of human organs and tissues for transplantation. In the last decade, the progress made in the field is remarkable, suggesting that clinical xenotransplantation procedures, particularly those involving cells, may become a reality in the not-too-distant future. However, several hurdles remain, mainly immunological barriers, physiological discrepancies, and safety issues, making xenotransplantion a complex and multidisciplinary discipline. © 2012 Springer Science+Business Media, LLC.

Xenotransplantation: An overview of the field

TISATO, Veronica;
2012

Abstract

Xenotransplantation, the transplantation of cells, tissues, or organs between different species, has the potential to overcome the current shortage of human organs and tissues for transplantation. In the last decade, the progress made in the field is remarkable, suggesting that clinical xenotransplantation procedures, particularly those involving cells, may become a reality in the not-too-distant future. However, several hurdles remain, mainly immunological barriers, physiological discrepancies, and safety issues, making xenotransplantion a complex and multidisciplinary discipline. © 2012 Springer Science+Business Media, LLC.
2012
978-161779844-3
Acute humoral xenograft rejection; Cellular rejection; Cellular transplantation; Hyperacute rejection; Molecular incompatibility; Tolerance; Transgenic animals; Xenotransplantation; Zoonoses; Animals; Cell Transplantation; Graft Survival; Humans; Organ Transplantation; Transplantation, Heterologous; Molecular Biology; Genetics
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2349699
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