The enhancing effect of preservatives on the in vitro permeation across rabbit nasal mucosa of desmopressin acetate (DDAVP) from nasal liquid formulations was studied. In particular, the enhancing mechanism of potassium sorbate was investigated.
In vitro permeation of desmopressin across rabbit nasal mucosa from liquid nasal sprays
BORTOLOTTI, Fabrizio;MENEGATTI, Enea;COLOMBO, Gaia
2008
Abstract
The enhancing effect of preservatives on the in vitro permeation across rabbit nasal mucosa of desmopressin acetate (DDAVP) from nasal liquid formulations was studied. In particular, the enhancing mechanism of potassium sorbate was investigated.File in questo prodotto:
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