Introduction: IMT by means of normocapnic hyperventilation is effective in improving exercise endurance in healthy subject but few data are available for COPD subjects Aim: to evaluate the effect of 4 weeks NH training by means of Spirotiger on respiratory parameters and exercise capacity in 21 moderate/severe COPD patients. Materials and Methods: 19 M, 2 F, aged 42-80. Respiratory function tests (FEV1, FVC, Pimax), QoL (St George’s Questionnaire), 6MWT and endurance exercise (75-80% of peak-work rate measured during an incremental test and performed to the limit of tolerance, tLIM). 7 of 21 patients were instrumented with a portable inductive plethysmografhy (Lifeshirt System) to evaluate breathing pattern during tLIM. After 1 month of weekly supervised training, the patients trained at home for 6 weeks: 10 min twice a day at a breathing rate 12-24/min with a volume equal to 50% of CV. Result: 6 patients dropped out (poor compliance). IMT significantly improved Pimax, QoL, exercise capacity (table1). Ventilatory pattern after IMT is characterized by a significantly higher TV with no change in VE (table2). Conclusion: after a short IMT, COPD patients show a higher exercise capacity and an intriguing change in ventilatory pattern which improves oxygen saturation. Table1 FEV1% FVC% Pimax(KPa) QoL(total) tLIM(min) 6MWD(m) Pre IMT 55,216,9 82,322,8 8,873 22,716,6 6,38 3,4 43674,5 Post IMT 57,615,8 82,724,1 9,582,8* 17,512,2* 10,297,4* 466,279,7* Table2 SpO2mean(%) VE(L/min) TV (L/min) Br(b/min) Pre IMT 912,2 28,616,1 0,80,4 334,2 Post IMT 92,31,5* 2916,4 0,90,4* 30,86,5 *p<0,05(statistical analysis by T test and Wilcoxon signed rank test)
Inspiratory muscle training (IMT) with normocapnic hyperventilation (NH) improves respiratory muscle strength, exercise performance and ventilatory pattern in COPD patients
POMIDORI, Luca;BERNARDI, EVA;GRASSI, Gianluca;MANDOLESI, Gaia;COGO, Annaluisa
2011
Abstract
Introduction: IMT by means of normocapnic hyperventilation is effective in improving exercise endurance in healthy subject but few data are available for COPD subjects Aim: to evaluate the effect of 4 weeks NH training by means of Spirotiger on respiratory parameters and exercise capacity in 21 moderate/severe COPD patients. Materials and Methods: 19 M, 2 F, aged 42-80. Respiratory function tests (FEV1, FVC, Pimax), QoL (St George’s Questionnaire), 6MWT and endurance exercise (75-80% of peak-work rate measured during an incremental test and performed to the limit of tolerance, tLIM). 7 of 21 patients were instrumented with a portable inductive plethysmografhy (Lifeshirt System) to evaluate breathing pattern during tLIM. After 1 month of weekly supervised training, the patients trained at home for 6 weeks: 10 min twice a day at a breathing rate 12-24/min with a volume equal to 50% of CV. Result: 6 patients dropped out (poor compliance). IMT significantly improved Pimax, QoL, exercise capacity (table1). Ventilatory pattern after IMT is characterized by a significantly higher TV with no change in VE (table2). Conclusion: after a short IMT, COPD patients show a higher exercise capacity and an intriguing change in ventilatory pattern which improves oxygen saturation. Table1 FEV1% FVC% Pimax(KPa) QoL(total) tLIM(min) 6MWD(m) Pre IMT 55,216,9 82,322,8 8,873 22,716,6 6,38 3,4 43674,5 Post IMT 57,615,8 82,724,1 9,582,8* 17,512,2* 10,297,4* 466,279,7* Table2 SpO2mean(%) VE(L/min) TV (L/min) Br(b/min) Pre IMT 912,2 28,616,1 0,80,4 334,2 Post IMT 92,31,5* 2916,4 0,90,4* 30,86,5 *p<0,05(statistical analysis by T test and Wilcoxon signed rank test)I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
