The data suggest that the B1 BK receptors may play a role in the physiopathology of epilepsy, and may represent a new interesting therapeutic target. Tools are available to challenge this idea both pharmacologically (using B1 and B2 receptor antagonists) and genetically (using B1 and B2 receptor knock-outs).
Induction of B1 bradykinin receptors in the kindled brain.
SIMONATO, Michele;MAZZUFERI, Manuela;RODI, Donata;BINASCHI, Anna;
2005
Abstract
The data suggest that the B1 BK receptors may play a role in the physiopathology of epilepsy, and may represent a new interesting therapeutic target. Tools are available to challenge this idea both pharmacologically (using B1 and B2 receptor antagonists) and genetically (using B1 and B2 receptor knock-outs).File in questo prodotto:
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