OLIVA, PAOLA
OLIVA, PAOLA
Dipartimento di Scienze Chimiche e Farmaceutiche (attivo dal 01/01/2012 al 31/12/2022)
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
2018 Romagnoli, Romeo; Kimatrai Salvador, Maria; Schiaffino Ortega, Santiago; Baraldi, Pier Giovanni; Oliva, Paola; Baraldi, Stefania; Lopez-Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Balzarini, Jan; Liekens, Sandra; Mattiuzzo, Elena; Basso, Giuseppe; Viola, Giampietro
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization
2018 Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Bortolozzi, Roberta; Viola, Giampietro
A 2a adenosine receptor: Structures, modeling, and medicinal chemistry
2018 Baraldi, S.; Baraldi, P. G.; Oliva, P.; Toti, K. S.; Ciancetta, A.; Jacobson, K. A.
A Facile Synthesis of Diaryl Pyrroles Led to the Discovery of Potent Colchicine Site Antimitotic Agents
2021 Romagnoli, Romeo; Oliva, Paola; Salvador, Maria Kimatrai; Manfredini, Stefano; Padroni, Chiara; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Maccarinelli, Federica; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
Apoptosis Pathways Triggered by a Potent Antiproliferative Hybrid Chalcone on Human Melanoma Cells
2021 Rodríguez, Irene; Saavedra, Ester; del Rosario, Henoc; Perdomo, Juan; Quintana, José; Prencipe, Filippo; Oliva, Paola; Romagnoli, Romeo; Estévez, Francisco
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors
2017 Rondanin, Riccardo; Fochi, Sara; Baruchello, Riccardo; Bernardi, Tatiana; Oliva, Paola; Semeraro, Floriana; Simoni, Daniele; Giannini, Giuseppe
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis
2022 Romagnoli, Romeo; Oliva, Paola; Prencipe, Filippo; Manfredini, Stefano; Germanò, Maria Paola; De Luca, Laura; Ricci, Federico; Corallo, Diana; Aveic, Sanja; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization
2020 Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Kimatrai Salvador, Maria; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Viola, Giampietro; Bortolozzi, Roberta; Persoons, Leentje; Balzarini, Jan; Liekens, Sandra; Schols, Dominique
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents
2017 Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Salvador, Maria Kimatrai; Lopez Cara, Luisa Carlota; Bortolozzi, Roberta; Mattiuzzo, Elena; Basso, Giuseppe; Viola, Giampietro
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors
2019 Romagnoli, Romeo; Oliva, Paola; Salvador, Maria Kimatrai; Camacho, Maria Encarnacion; Padroni, Chiara; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Grillo, Elisabetta; Bortolozzi, Roberta; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors
2019 Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Schiaffino Ortega, Santiago; Chayah, Mariem; Kimatrai Salvador, Maria; Lopez-Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Mattiuzzo, Elena; Viola, Giampietro
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
2020 Oliva, Paola; Romagnoli, Romeo; Manfredini, Stefano; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Maccarinelli, Federica; Giacomini, Arianna; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting
2018 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, M P; Vignudelli, T; Luciani, R; Matassa, D S; Esposito, F; Landriscina, M
Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole Scaffold
2022 Zurlo, Matteo; Romagnoli, Romeo; Oliva, Paola; Gasparello, Jessica; Finotti, Alessia; Gambari, Roberto
Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti-tubulin tetrahydrothieno[2,3-c]pyridine derivative and a peptide nucleic acid targeting miR-221-3p
2021 Zurlo, M.; Romagnoli, R.; Oliva, P.; Gasparello, J.; Finotti, A.; Gambari, R.
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents
2017 Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Salvador, Maria Kimatrai; Lopez Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Porcù, Elena; Basso, Giuseppe; Viola, Giampietro
Synthesis and biological evaluation of 2-substituted benzyl-/phenylethylamino-4-amino-5-aroylthiazoles as apoptosis-inducing anticancer agents
2020 Oliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco; Quintana, José; Estévez, Francisco; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Romagnoli, Romeo
Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells
2018 Romagnoli, Romeo; Prencipe, Filippo; Lopez-Cara, Luisa Carlota; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Estévez-Sarmiento, Francisco; Quintana, José; Estévez, Francisco
Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents
2022 Oliva, Paola; Romagnoli, Romeo; Cacciari, Barbara; Manfredini, Stefano; Padroni, Chiara; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Corallo, Diana; Aveic, Sanja; Milan, Noemi; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
Synthesis and biological evaluation of new antitubulin agents containing 2-(30,40,50-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
2020 Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Cacciari, Barbara; Balzarini, Jan; Liekens, Sandra; Hamel, Ernest; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Zurlo, Matteo; Finotti, Alessia; Gambari, Roberto
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition | 2018 | Romagnoli, Romeo; Kimatrai Salvador, Maria; Schiaffino Ortega, Santiago; Baraldi, Pier Giovanni; ...Oliva, Paola; Baraldi, Stefania; Lopez-Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Balzarini, Jan; Liekens, Sandra; Mattiuzzo, Elena; Basso, Giuseppe; Viola, Giampietro | |
| 3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization | 2018 | Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Bra...ncale, Andrea; Ferla, Salvatore; Hamel, Ernest; Bortolozzi, Roberta; Viola, Giampietro | |
| A 2a adenosine receptor: Structures, modeling, and medicinal chemistry | 2018 | Baraldi, S.; Baraldi, P. G.; Oliva, P.; Toti, K. S.; Ciancetta, A.; Jacobson, K. A. | |
| A Facile Synthesis of Diaryl Pyrroles Led to the Discovery of Potent Colchicine Site Antimitotic Agents | 2021 | Romagnoli, Romeo; Oliva, Paola; Salvador, Maria Kimatrai; Manfredini, Stefano; Padroni, Chiara; B...rancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Maccarinelli, Federica; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta | |
| Apoptosis Pathways Triggered by a Potent Antiproliferative Hybrid Chalcone on Human Melanoma Cells | 2021 | Rodríguez, Irene; Saavedra, Ester; del Rosario, Henoc; Perdomo, Juan; Quintana, José; Prencipe, F...ilippo; Oliva, Paola; Romagnoli, Romeo; Estévez, Francisco | |
| Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors | 2017 | Rondanin, Riccardo; Fochi, Sara; Baruchello, Riccardo; Bernardi, Tatiana; Oliva, Paola; Semeraro,... Floriana; Simoni, Daniele; Giannini, Giuseppe | |
| Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis | 2022 | Romagnoli, Romeo; Oliva, Paola; Prencipe, Filippo; Manfredini, Stefano; Germanò, Maria Paola; De ...Luca, Laura; Ricci, Federico; Corallo, Diana; Aveic, Sanja; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta | |
| Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization | 2020 | Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Kimatrai Salvador, Maria; Brancale, Andrea; Fe...rla, Salvatore; Hamel, Ernest; Viola, Giampietro; Bortolozzi, Roberta; Persoons, Leentje; Balzarini, Jan; Liekens, Sandra; Schols, Dominique | |
| Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents | 2017 | Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Sal...vador, Maria Kimatrai; Lopez Cara, Luisa Carlota; Bortolozzi, Roberta; Mattiuzzo, Elena; Basso, Giuseppe; Viola, Giampietro | |
| Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors | 2019 | Romagnoli, Romeo; Oliva, Paola; Salvador, Maria Kimatrai; Camacho, Maria Encarnacion; Padroni, Ch...iara; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Grillo, Elisabetta; Bortolozzi, Roberta; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro | |
| Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors | 2019 | Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Sch...iaffino Ortega, Santiago; Chayah, Mariem; Kimatrai Salvador, Maria; Lopez-Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Mattiuzzo, Elena; Viola, Giampietro | |
| Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors | 2020 | Oliva, Paola; Romagnoli, Romeo; Manfredini, Stefano; Brancale, Andrea; Ferla, Salvatore; Hamel, E...rnest; Ronca, Roberto; Maccarinelli, Federica; Giacomini, Arianna; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta | |
| New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting | 2018 | Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi..., T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, M P; Vignudelli, T; Luciani, R; Matassa, D S; Esposito, F; Landriscina, M | |
| Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole Scaffold | 2022 | Zurlo, Matteo; Romagnoli, Romeo; Oliva, Paola; Gasparello, Jessica; Finotti, Alessia; Gambari, Ro...berto | |
| Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti-tubulin tetrahydrothieno[2,3-c]pyridine derivative and a peptide nucleic acid targeting miR-221-3p | 2021 | Zurlo, M.; Romagnoli, R.; Oliva, P.; Gasparello, J.; Finotti, A.; Gambari, R. | |
| Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents | 2017 | Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Sal...vador, Maria Kimatrai; Lopez Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Porcù, Elena; Basso, Giuseppe; Viola, Giampietro | |
| Synthesis and biological evaluation of 2-substituted benzyl-/phenylethylamino-4-amino-5-aroylthiazoles as apoptosis-inducing anticancer agents | 2020 | Oliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco; Quin...tana, José; Estévez, Francisco; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Romagnoli, Romeo | |
| Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells | 2018 | Romagnoli, Romeo; Prencipe, Filippo; Lopez-Cara, Luisa Carlota; Oliva, Paola; Baraldi, Stefania; ...Baraldi, Pier Giovanni; Estévez-Sarmiento, Francisco; Quintana, José; Estévez, Francisco | |
| Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents | 2022 | Oliva, Paola; Romagnoli, Romeo; Cacciari, Barbara; Manfredini, Stefano; Padroni, Chiara; Brancale..., Andrea; Ferla, Salvatore; Hamel, Ernest; Corallo, Diana; Aveic, Sanja; Milan, Noemi; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta | |
| Synthesis and biological evaluation of new antitubulin agents containing 2-(30,40,50-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold | 2020 | Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Cacciari, Barbara; Balzarini, Jan; Liekens, Sa...ndra; Hamel, Ernest; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Zurlo, Matteo; Finotti, Alessia; Gambari, Roberto |